Itraconazole-Induced Apoptosis in Candida glabrata (Nakaseomyces glabratus) Biofilms: Role of ROS and CgPDR 1 Mutations (K274N, D1082G, and S343F) in Resistant Clinical Isolates
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Background: Nakaseomyces glabratus exhibits intrinsic tolerance to azole antifungals, frequently mediated by gain-of-function (GOF) mutations in the transcription factor CgPDR1. While efflux-mediated resistance is well establishe... ...
