Investigating the validity of mCIM and sCIM phenotypic methods in screening Pseudomonas aeruginosa isolates producing IMP, VIM, and NDM metallo-beta-lactamases isolated from burn wounds [0.03%]
探讨mCIM和sCIM表型方法筛查烧伤创面分离的产IMP、VIM和NDM金属β-内酰胺酶肺炎克雷伯菌的有效性
Hossein Hatami,Shiva Motamedi,Ghazaleh Talebi et al.
Hossein Hatami et al.
Metallo-beta-lactamase-producing Pseudomonas aeruginosa (P. aeruginosa) is a major pathogen in burn wounds, often exhibiting high levels of antibiotic resistance, which complicates treatment strategies. This study deals with the validity of...
Aztreonam-avibactam: a new combination with activity against multidrug-resistant Klebsiella pneumoniae complex [0.03%]
阿维巴坦-奥默宁：一种对多重耐药肺炎克雷伯菌复合群有活性的新组合疗法
Alicja Sękowska
Alicja Sękowska
Klebsiella pneumoniae complex (KPc) is a group of opportunistic pathogens that pose a serious threat to public health. Multidrug resistance is increasing, and limiting therapeutic options. Aztreonam-avibactam (AZA) is a combination of an es...
Jinhua Zhang,Hongjiang Xu,Yuanzhen Dong et al.
Jinhua Zhang et al.
Based on DMR022 [(AEEA-Gly)2-AEEA-amphotericin B methyl ester, AEEA is the abbreviation of 8-amino-3,6-dioxaoctanoic acid] and DMR031 [(AEEA)5-amphotericin B methyl ester], DMR040 [(AEEA)2-amphotericin B methyl ester] was further designed a...
Cryptoic acids A and B, benzene-containing polyketides, and cyclocryptamide, a modified diketopiperazine, from an actinomycete of the genus Cryptosporangium [0.03%]
链霉菌产生的一种隐孢菌化合物A和B，含苯环聚酮类酸和环隐素胺，一种修饰的二酮哌嗪类化合物
Md Julkar Nime,Hideki Yamamura,Masayuki Hayakawa et al.
Md Julkar Nime et al.
Two new benzene-containing polyketides, cryptoic acids A (1) and B (2), along with a new acylated diketopiperazine designated cyclocryptamide (3), were isolated from the culture extract of Cryptosporangium sp. YDKA-T02. The absolute configu...
Richard E Lee,Minoru Yoshida
Richard E Lee
Activity of cefiderocol in combination with tetracycline analogues against carbapenem-resistant Acinetobacter baumannii [0.03%]
塞来西托olum针对碳青霉烯类耐药鲍曼不动杆菌与四环素类似物联合应用的活性研究
Yuhan Yin,Na Xu,Xinjie Wang
Yuhan Yin
Therapeutic options for carbapenem-resistant Acinetobacter baumannii (CA-AB) are quite limited. Cefiderocol, a novel siderophore cephalosporin, has shown potent in vitro activity against CR-AB, and new tetracycline analogues such as eravacy...
Therapeutic potential of isoallolithocholic acid in methicillin-resistant Staphylococcus Aureus peritoneal infection [0.03%]
异石胆酸在耐甲氧西林金黄色葡萄球菌腹膜感染中的治疗潜力
Ying Lu,Jun Du,Shicheng Peng et al.
Ying Lu et al.
A significant increase in multidrug-resistant Methicillin-resistant Staphylococcus aureus (MRSA) infections has made it crucial to explore new antimicrobial drugs and strategies. Emerging evidence suggests that the bile acid metabolite isoa...
Yoshimasa Ishizaki,Chigusa Hayashi,Kazuaki Matoba et al.
Yoshimasa Ishizaki et al.
Multidrug-resistant Neisseria gonorrhoeae is a pathogenic bacterium that poses a public health concern. In this study, we aimed to elucidate the mode of action of the conventional antibiotic novobiocin, which has been selected as a leading ...