Callum Schofield,Marie Reid,Ivana Markova et al.
Callum Schofield et al.
BackgroundWeight loss and eating difficulties are common in Huntington's disease (HD), but professionals' perspectives remain underexplored.ObjectiveTo investigate professionals and service users' perspectives on weight loss and eating diff...
Experiences and perceptions of affected individuals, families, caregivers and healthcare professionals regarding end-of-life planning in Huntington's disease: A narrative synthesis [0.03%]
亨廷顿病患者、家属、照料者及医疗保健专业人员关于生命末期规划的经历和认知：叙述性综合分析
Catherine Lyon,Chris Williams,Suzanne Buswell et al.
Catherine Lyon et al.
IntroductionPeople with Huntington's disease (HD) are encouraged to consider end-of-life planning early on to mitigate future challenges. Initial evidence shows that undertaking planning discussions around this subject presents various barr...
A clinimetric evaluation of the problem behaviors assessment short form (PBA-s) within the context of the Huntington's disease integrated staging system (HD-ISS) [0.03%]
亨廷顿病综合分期系统中的问题行为评估简表（PBA-S）的临床计量学评价
Docia L Demmin,Matthew W Roché,Jatin G Vaidya et al.
Docia L Demmin et al.
Background/objective: This study extends prior clinimetric evaluations by examining the factor structure, internal consistency, and distributional properties of the Problem Behaviors Assessment - Short Form (PBA-s) in a l...
Novel monoclonal antibodies against the C-terminal HEAT domain of huntingtin [0.03%]
靶向亨廷顿蛋白C端HEAT结构域的新型单克隆抗体
Yang-Nim Park,Rebeka Fanti,Samira Sadeghi et al.
Yang-Nim Park et al.
BackgroundReliable detection of huntingtin (HTT) is essential for understanding Huntington's disease (HD) biology and for evaluating therapeutic strategies. However, high-quality monoclonal antibodies (mAbs) against the HTT C-terminal domai...
A moderate-intensity exercise program during inpatient rehabilitation for middle stage Huntington's disease: A randomized controlled trial [0.03%]
中强度运动干预亨廷顿病中间期住院康复的疗效研究：一项随机对照试验
Mathis Brusseau,Brigitte Soudrie,Anne-Catherine Bachoud-Lévi et al.
Mathis Brusseau et al.
BackgroundExercise is beneficial for persons with Huntington's disease (HD). Inpatient rehabilitation settings are well-suited for implementing exercise programs. Exercise parameters, such as duration and intensity, need to be further inves...
Contribution of neuroepigenetics to HD - developmental and aging-related signatures [0.03%]
神经表观遗传学在亨廷顿舞蹈病中的作用——发育和衰老相关标志
Jil Scuto,Noémie Penaud,Karine Merienne
Jil Scuto
Huntington's disease (HD) is a neurodegenerative disorder triggered by an unstable expansion of CAG repeats in the coding sequence of the HTT gene. Among the neuronal populations affected, striatal spiny projection neurons (SPNs) show parti...
Marine Degennaro,Sandrine Humbert,Mariacristina Capizzi
Marine Degennaro
One of the great mysteries of Huntington disease (HD) is its adult onset. HD is caused by a CAG repeat expansion in the HTT gene, which encodes a protein (HTT) that is crucial for intracellular transport and neuronal growth, so one would ex...
Alleviation of cerebellar impairment, cognitive decline, and depression by a chlorzoxazone-folic acid combination in a Huntington's disease transgenic mouse model [0.03%]
氯扎扎酮-叶酸组合在亨廷顿舞蹈病转基因小鼠模型中改善小脑功能障碍、认知衰退和抑郁
Ksenia S Marinina,Daria S Malkova,Ilya B Bezprozvanny et al.
Ksenia S Marinina et al.
Huntington's disease (HD) is a hereditary neurodegenerative condition, passed down in an autosomal dominant manner, characterized by the gradual decline of motor functions, such as chorea, along with psychiatric symptoms and cognitive deter...
Exploring quality of care through the eyes of formal and informal caregivers for residents with Huntington's disease: A qualitative descriptive study [0.03%]
透过正式和非正式看护者的眼光探索亨廷顿病患者护理质量：一项描述性研究
Joyce Cf Heffels,Irma Hj Everink,Raymund Ac Roos et al.
Joyce Cf Heffels et al.
AimTo gain insight into factors contributing to the quality of care in nursing homes specialized in Huntington's disease from the perspectives of formal and informal caregivers.DesignA qualitative descriptive focus group study.MethodsFormal...
Letter in response to Salari M, et al. Epidemiology and clinical features of Huntington's disease in MENASA region: A systematic review and meta-analysis [0.03%]
对萨拉里等人关于中东和北非地区亨廷顿病的流行病学及临床特征系统评价和荟萃分析的来信响应
Oliver W Quarrell,Alexander Thompson,Mark Strong
Oliver W Quarrell