Benzo[a]pyrene exacerbates atherosclerosis by upregulating SPP1 to promote macrophage inflammation and lipid dysregulation: An integrated network toxicology, RNA-seq, and experimental validation study [0.03%]
苯并[a]芘通过上调SPP1促进巨噬细胞炎症和脂质紊乱从而加重动脉粥样硬化的网络毒理学、RNA测序及实验验证研究
Runwen Li,Jieting Zheng,Yongjiang Tang et al.
Runwen Li et al.
Benzo[a]pyrene (BaP), a pervasive environmental pollutant, has been implicated in cardiovascular injury, yet its mechanistic contribution to atherosclerosis remains unclear. Here, we combined network toxicology, RNA-seq profiling, molecular...
Colchicine inhibits macrophage motility and matrix degradation through microtubule disruption [0.03%]
秋水仙素通过破坏微管抑制巨噬细胞的运动和基质降解
Mansi Vansjariya,Aaron L Magno,Fiona J Pixley et al.
Mansi Vansjariya et al.
Background: Atherosclerosis is a chronic inflammatory process wherein macrophages play a central role in the evolution of arterial wall plaques in extracellular matrix. Colchicine, a drug used most commonly to treat gout,...
Therapeutic perspective on cardiomyopathy and heart failure in older adults through the lens of chronic inflammation [0.03%]
慢性炎症视角下老年人心肌病和心力衰竭的治疗展望
Hongyu Qiu,Inna P Gladysheva
Hongyu Qiu
Cardiomyopathy is a disorder of the myocardium characterized by structural and functional abnormalities that result in impaired cardiac mechanical and/or electrical function. Aging induces a natural, gradual decline in cardiac structure and...
Corrigendum to "Hemodynamic markers: CFD-based prediction of cerebral aneurysm rupture risk" [Vascular Pharmacology 162 (2026) 107578] [0.03%]
关于“血流动力学标志物：基于计算流体动力学的脑动脉瘤破裂风险预测”的勘误[Vascular Pharmacology 162 (2026) 107578]
Reza Bozorgpour
Reza Bozorgpour
Published Erratum
Vascular pharmacology. 2026 Feb 5:107584. DOI:10.1016/j.vph.2026.107584 2026
Real-world observational study on pulmonary arterial hypertension: Italian cohort treated with macitentan and/or selexipag as a part of a combination treatment (INSPECTIO) [0.03%]
意大利真实世界观察性肺动脉高压研究：与玛西腾坦和/或塞利舒帕联合用药的患者群体（INSPECTIO研究）
Michele D&#x;Alto,Laura Scelsi,Livio Giuliani et al.
Michele D&#x;Alto et al.
Background: Pulmonary arterial hypertension (PAH) is a progressive disease associated with significant morbidity and mortality. Combination therapy targeting multiple pathways has been shown to improve clinical outcomes. ...
Geoffrey E Woodard
Geoffrey E Woodard
The human heart exhibits remarkable chamber-specific ion channel expression patterns that underlie the distinct electrophysiological properties of atrial versus ventricular myocardium. This comprehensive review examines the molecular archit...
Angiogenic and anti-angiogenic factors are the shared mechanistic pathways between preeclampsia and Alzheimer's disease: Perspective and take-away [0.03%]
血管生成和抗血管生成因子是先兆子痫和阿尔茨海默病的共同机制途径：观点和启示
Anass M Abbas,Hayder M Al-Kuraishy,Thabat Jumaah Al-Maiahy et al.
Anass M Abbas et al.
Preeclampsia (PE), a major hypertensive disorder of pregnancy, is increasingly recognized as a significant risk factor for cognitive decline and Alzheimer's disease (AD). Placental ischemia in PE leads to an anti-angiogenic state, character...
Tirzepatide mitigates thoracic aortic aneurysm and dissection by alleviating the loss of the contractile phenotype in vascular smooth muscle cells and reducing vascular inflammation [0.03%]
tirzepatide通过减轻血管平滑肌细胞收缩表型的丧失和减少血管炎症来缓解胸主动脉瘤和夹层
Liao Tan,Jie Liu,Ruizheng Shi et al.
Liao Tan et al.
Background: Thoracic aortic aneurysm and dissection (TAAD) is a kind of life-threatening cardiovascular condition with a poor prognosis, currently lacking effective drug therapies that can halt the progression of TAAD. Ti...
Exercise pulmonary hypertension in chronic thromboembolic pulmonary disease without resting pulmonary hypertension: A systematic review and meta-analysis [0.03%]
慢性血栓栓塞性肺疾病患者的运动性肺动脉高压：一项系统评价和荟萃分析
Filippo Biondi,Sandra Ghelardoni,Doralisa Morrone et al.
Filippo Biondi et al.
Exercise pulmonary hypertension (exPH) is currently defined as a mean pulmonary artery pressure to cardiac output slope (mPAP/CO slope) greater than 3 mmHg/L/min during the transition from rest to end-exercise, and a normal mPAP at rest. Ex...
Endothelial-to-mesenchymal transition primes vascular endothelial cells toward an osteochondrogenic fate [0.03%]
内皮细胞向间充质细胞转化使血管内皮细胞倾向于成软骨和成骨命运转换
Franceska Kishta,Ignacio Fernando Hall,Guanliang Li et al.
Franceska Kishta et al.
Endothelial-to-mesenchymal transition (EndMT), in which endothelial cells (ECs) lose their endothelial identity and acquire mesenchymal-like features, contributes to vascular dysfunction and remodeling in atherosclerosis. However, the fate ...