Peptides derived from the C-terminal domain of HIV-1 Viral Protein R in lipid bilayers: Structure, membrane positioning and gene delivery [0.03%]
HIV-1病毒蛋白R的C端结构域衍生肽在脂质双层中的结构、膜定位和基因传递功能
Arnaud Marquette,Christian Leborgne,Vanessa Schartner et al.
Arnaud Marquette et al.
Viral protein R (Vpr) is a small accessory protein of 96 amino acids that is present in Human and simian immunodeficiency viruses. Among the very different properties that Vpr possesses we can find cell penetrating capabilities. Based on th...
Molecular insights into the effect of an apoptotic raft-like bilayer on the conformation and dynamics of calreticulin [0.03%]
凋亡筏状双层膜对钙网蛋白构象和动力学影响的分子机制研究
Lingyun Wang,Yuhua Song
Lingyun Wang
Cell surface calreticulin (CRT) can mediate apoptotic cells removal by binding and activating LDL receptor-related protein (LRP1). Phosphatidylserine (PS) lipids in the inner leaflet of the cell membrane are externalized and become exposed ...
Increase in the current variance in bilayer lipid membranes near phase transition as a result of the occurrence of hydrophobic defects [0.03%]
双层脂质膜中的临界现象及疏水缺陷的影响
A A Anosov,E Yu Smirnova,A A Sharakshane et al.
A A Anosov et al.
Most researchers associate the increase in the permeability of lipid bilayers of artificial and biological membranes observed in various experiments with the formation of hypothetical hydrophobic and hydrophilic pores. Although the existenc...
Tomohito Higashi,Hideki Chiba
Tomohito Higashi
Tricellular junctions are specialized cell-cell junctions formed at sites where three epithelial or endothelial cells make contact at their apical side. By holding three cells together, tricellular junctions contribute to the maintenance of...
OxLDL alterations in endothelial cell membrane dynamics leads to changes in vesicle trafficking and increases cell susceptibility to injury [0.03%]
氧化低密度脂蛋白改变影响内皮细胞膜动态过程并改变囊泡转运从而增加细胞损伤的易感性
Natália Fernanda Couto,Luisa Rezende,Weslley Fernandes-Braga et al.
Natália Fernanda Couto et al.
Plasma membrane repair (PMR) is an important process for cell homeostasis, especially for cells under constant physical stress. Repair involves a sequence of Ca2+-dependent events, including lysosomal exocytosis and subsequent compensatory ...
Special Issue: Molecular Biophysics of Membranes and Membrane Proteins: Preface [0.03%]
分子膜和膜蛋白生物物理专题：导语
Lynmarie K Thompson,Merritt Maduke
Lynmarie K Thompson
Sven C D van IJzendoorn,Jean Agnetti,Ama Gassama-Diagne
Sven C D van IJzendoorn
Epithelial cells are polarized cells and typically display distinct plasma membrane domains: basal plasma membrane domains face the underlying tissue, lateral domains contact adjacent cells and apical domains face the exterior lumen. Each m...
Myelin basic protein (MBP) charge variants show different sphingomyelin-mediated interactions with myelin-like lipid monolayers [0.03%]
脱髓鞘相关髓鞘碱性蛋白(MBP)电荷异构体显示出与类似髓磷脂的单层脂质不同的鞘氨醇磷脂介导的相互作用
Katharina Widder,George Harauz,Dariush Hinderberger
Katharina Widder
Multiple sclerosis (MS) is correlated with increased deimination of myelin basic protein (MBP) in the central nervous system. Here, the interaction of MBP C1 (charge: +19) and MBP C8 (charge: +13) with the major lipids of the cytoplasmic si...
Polarity of the ATP binding site of the Na+,K+-ATPase, gastric H+,K+-ATPase and sarcoplasmic reticulum Ca2+-ATPase [0.03%]
钠钾/胃黏膜钾 proton/肌浆网钙 原型酶的ATP结合部位的极性
K R Hossain,X Li,T Zhang et al.
K R Hossain et al.
A fluorescence ratiometric method utilizing the probe eosin Y is presented for estimating the ATP binding site polarity of P-type ATPases in different conformational states. The method has been calibrated by measurements in a series of alco...
Isoflurane increases cell membrane fluidity significantly at clinical concentrations [0.03%]
异氟烷在临床浓度时明显增加细胞膜的流动性
Jigesh Patel,Ekram A Chowdhury,Behnam Noorani et al.
Jigesh Patel et al.
There is an on-going debate whether anesthetic drugs, such as isoflurane, can cause meaningful structural changes in cell membranes at clinical concentrations. In this study, the effects of isoflurane on lipid membrane fluidity were investi...