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Molecular insights into the effect of an apoptotic raft-like bilayer on the conformation and dynamics of calreticulin

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Cell surface calreticulin (CRT) can mediate apoptotic cells removal by binding and activating LDL receptor-related protein (LRP1). Phosphatidylserine (PS) lipids in the inner leaflet of the cell membrane are externalized and become exposed in cholesterol (CHOL... ...