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期刊名:Biochimica et biophysica acta-molecular basis of disease

缩写:BBA-MOL BASIS DIS

ISSN:0925-4439

e-ISSN:1879-260X

IF/分区:4.2/Q1

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共收录本刊相关文章索引2446
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Yihan Shen,Jingru Wang,Lifang Ye et al. Yihan Shen et al.
Cardiac remodeling underlies the progression to heart failure, yet the molecular drivers remain incompletely defined. Here, we identify fibroblast growth factor binding protein 1 (FGFBP1) as a previously unrecognized regulator of pathologic...
Gangfeng Ding,Jiayao He,Yichao Chen et al. Gangfeng Ding et al.
Esophageal cancer (EC) is a highly aggressive malignancy associated with high rates of recurrence and metastasis, and the five-year survival rate remains only 20-30%. N6-methyladenosine (m6A), the most abundant mRNA modification, plays a pi...
Yujie Liu,Rong Chen,Gexi Liu et al. Yujie Liu et al.
Glioblastoma multiforme (GBM) is the most prevalent primary brain tumor in adults and characterized by high therapeutic resistance and poor prognosis, in which the repair of DNA damage plays a significant role, highlighting the need to eluc...
Yue Guo,Meng-Yuan Liu,Yun-Qi Mo et al. Yue Guo et al.
Hepatic fibrosis, a hallmark of chronic liver diseases, arises from persistent activation of hepatic stellate cells (HSCs). Golgi protein 73 (GP73) is a recognized fibrosis biomarker, yet its active role in driving fibrogenesis and the unde...
Changhui Geng,Peng Chen,Zhihui Wang et al. Changhui Geng et al.
Background: Colorectal cancer (CRC) is a major global health burden with limited therapeutic efficacy, highlighting the need for novel pathogenic insights and therapeutic targets. Tissue Inhibitor of Metalloproteinase 1 (...
Kellianne M Piell,Anna Vallarta,Ali E Wilt et al. Kellianne M Piell et al.
The N-6-methyladenosine (m6A) modification of mRNA regulates transcript abundance in endocrine therapy (ET)-resistant breast cancer (BCa) cells. We reported that m6A reader HNRNPA2B1 decreased miR-145p and miR-424-5p targeting PSAT1 and miR...
Fan Liu,Fei Zhao,Mengge Du et al. Fan Liu et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) increases the risk of developing steatohepatitis, liver cirrhosis, and liver cancer. Neddylation, a ubiquitin-like post-translational modification, has been proven to play a c...
Ziyu Zhang,Xiangting Jin,Junhong Chen et al. Ziyu Zhang et al.
Kelch-like ECH-associated protein 1 (KEAP1) serves as an adaptor protein for the Cullin3-RING E3 ubiquitin ligase complex, orchestrating the ubiquitination and subsequent degradation of its substrates including the transcription factor NF-E...
Yan Guo,Yuanyong Feng,Xiangning Ni et al. Yan Guo et al.
Oral squamous cell carcinoma (OSCC) is a common malignant tumor in the head and neck region and clinically characterized by relatively high invasiveness and a propensity for metastasis. Patients generally exhibit nonsatisfactory prognosis. ...