Optimal screening strategies, colonization rates, and antimicrobial resistance within a newly implemented organized group B Streptococcus screening program in Slovenia [0.03%]
斯洛文尼亚新实施的组织化B群链球菌筛查计划中的最佳筛查策略、定植率和抗微生物耐药性研究
Julija Germ,Polona Maver Vodičar
Julija Germ
Introduction: Streptococcus agalactiae (group B Streptococcus, GBS) is a major cause of early-onset neonatal infections, with maternal GBS colonization being the primary risk factor. Despite a neonatal GBS incidence excee...
Antiviral resistance testing for DNA viruses in immunocompromised patients: Mechanisms, clinical utility, and limitations [0.03%]
免疫缺陷患者DNA病毒抗病毒耐药检测：机制、临床应用及局限性
Diego R Hijano,Linlin Gu,Benjamin M Liu et al.
Diego R Hijano et al.
Immunocompromised patients, including transplant recipients, individuals receiving chemotherapy or chronic immunosuppression, and those with primary or acquired immunodeficiency, are at increased risk for severe viral infections and treatme...
Refractory Candida orthopsilosis endocarditis in a hemodialysis patient: The role of species-level identification and surgical source control [0.03%]
血透患者难治性尖端木瓜霉(endocarditis)：种类水平鉴定和外科手术控制感染灶的作用
Maria Eduarda Pierre,Alessandro Pascon Filho,José Alberto Kfouri da Silva Trazzi et al.
Maria Eduarda Pierre et al.
Purpose: Candida orthopsilosis endocarditis is rare and underdiagnosed due to the inability of conventional biochemical platforms to achieve species-level identification within the Candida parapsilosis complex. ...
Comparative evaluation and analytical performance of four lipL32-based qPCR assays for detection of pathogenic Leptospira spp [0.03%]
四种基于lipL32的qPCR测定法检测病原性钩端螺旋体的比较评价及分析性能
Gustavo Guilherme Soares Viana,Marcos Bryan Heinemann,Ana Catharina de Seixas Santos Nastri et al.
Gustavo Guilherme Soares Viana et al.
Background: Leptospira spp. cause leptospirosis, a globally distributed zoonosis with significant morbidity in tropical regions. Early diagnosis is challenging, particularly in the acute phase when serological markers may...
Intracerebral hemorrhage in disseminated histoplasmosis in advanced HIV infection: A case report [0.03%]
艾滋病晚期播散性组织胞浆菌病 intracerebral出血一例报告
Anthony Ayala-Inga,Alfredo Rebaza-Mateo,Juan Carlos Díaz-Monge et al.
Anthony Ayala-Inga et al.
Background: Disseminated histoplasmosis is a severe systemic mycosis typically seen in immunocompromised individuals. Though CNS involvement occurs in a small subset of patients, associated intracranial hemorrhage is an e...
The great imitator behind an ischemic stroke: a case of meningovascular syphilis [0.03%]
伟大的模仿者——缺血性卒中的幕后黑手：一期梅毒并发脑血管病变一例
Emilio Altavilla,Luca Bortolani,Anna Carraro et al.
Emilio Altavilla et al.
Neurosyphilis is a rare but reversible cause of ischemic stroke. We report a 41-year-old male with no cardiovascular risk factors initially diagnosed with Bell's palsy for left facial weakness. Four days later, he developed left-sided hemip...
An extraction-free multiplex RT-PCR assay for simultaneous detection of six respiratory pathogens using polychromatic melting curve analysis [0.03%]
一种无提取多重RT-PCR方法利用多色熔解曲线分析同时检测六种呼吸道病原体
Ya Bian,Lishan Lu,Xiaohan Ma et al.
Ya Bian et al.
Objectives: Acute respiratory infections commonly result from a spectrum of pathogens, including SARS-CoV-2, influenza A (IAV) and B viruses (IBV), respiratory syncytial virus (RSV), human adenovirus (HAdV), and Mycoplasm...
Evaluation of the performance of reverse transcription-recombinase polymerase amplification (RT-RPA) coupled with CRISPR/Cas12a and microfluidics for one-step detection of common HCV genotypes [0.03%]
评估逆转录重组酶聚合酶扩增(RT-RPA)结合CRISPR/Cas12a和微流控芯片一步检测常见HCV基因型的性能
Qiong Wang,Yushu Wang,Tian Jia et al.
Qiong Wang et al.
Background: Hepatitis C virus (HCV) genotyping is critical for guiding therapy, yet current methods are technically demanding and time-consuming. Aim: ...
Comparison of diagnostic modalities for Mycoplasma pneumoniae detection in pediatric respiratory infections: A single-centre cross-sectional study from India [0.03%]
印度儿科呼吸道感染患者支原体肺炎检测方法比较：一项单中心横断面研究
Sajitha Venkatesan,Tushar Jagzape,Archana Keche et al.
Sajitha Venkatesan et al.
Background: Mycoplasma pneumoniae (MP) is a key cause of community-acquired pneumonia (CAP) in children. Accurate laboratory diagnosis is essential for appropriate therapy and prevention of complications. However, variabl...
Discovery and functional characterization of katG mutations mediating Isoniazid resistance in Mycobacterium tuberculosis [0.03%]
卡那霉素耐药结核分枝杆菌的katG基因突变的功能表征和发现
Qirong Wang,Yang Liu,Yingzhi Chong et al.
Qirong Wang et al.
Objective: To identify isoniazid (INH)-resistance-associated mutations in the katG of Mycobacterium tuberculosis (MTB) using whole genome sequencing (WGS) and validate mutations through functional studies. ...