Viral metagenomic sequencing reveals rare pathogens and improves diagnostic accuracy in neuroinflammatory disorders [0.03%]
病毒宏基因组测序可发现罕见病原体并提高神经炎症性疾病诊断的准确性
Ian Pichler,Elisabeth Krischer,Tilman Obenhuber et al.
Ian Pichler et al.
Background: Neuroinflammatory disorders are frequently of unknown aetiology. Unbiased metagenomic next-generation sequencing of cerebrospinal fluid could help bridge the current diagnostic gap by identifying more infectio...
Surprising uncovering of gram-negative diplococci from blood cultures: First identification of Pseudoroseomonas aerofrigidensis as probable bloodstream infection - clinical and laboratory approach towards an unknown pathogen [0.03%]
血培养意外发现革兰氏阴性双球菌:Pseudoroseomonas aerofrigidensis 首次鉴定为疑似引起血液感染的病原菌-临床和实验室未知病原菌处理方法
Stefan Schlabe,Galina Asseva,Ursula Brands-Jordan et al.
Stefan Schlabe et al.
Identification of pathogens has been accelerated by MALDI-TOF, including very rare bacteria, which can challenge routine diagnostics by uncommon features. Moreover, rare or only recently discovered microorganisms often lack experience or da...
Toward a clinical algorithm for the detection of periprosthetic joint infections using targeted NGS [0.03%]
基于目标NGS的假体周围关节感染检测临床算法的研究
Ander Uribarri,Lucia Henriquez,Iñaki Beguiristain et al.
Ander Uribarri et al.
Objectives: Periprosthetic joint infection (PJI) represents a severe surgical complication, and despite advances have been made in PJI diagnosis, many cases remain microbiologically negative. In this context, metagenomic ...
High-risk HPV genotype distribution and prevalence in cervical swabs from Western Turkey [0.03%]
土耳其西部宫颈涂片的高危人乳头瘤病毒基因型分布和流行率
Nurefşan Erdiren,Tuğba Kula Atik,Gülay Turan et al.
Nurefşan Erdiren et al.
This retrospective study analyzed HPV-DNA genotyping, cytological, and histopathological findings from cervical swab samples of women aged 18 and older who attended the Gynecology and Obstetrics outpatient clinic at Balıkesir University He...
Laboratory diagnosis of rabies in an endemic country: Progress and challenges on the path to elimination [0.03%]
犬儒病的实验室诊断:消除道路上的进步与挑战
M A Ashwini,Lonika Lodha,Arya Ramachandran et al.
M A Ashwini et al.
Background: Rabies is a fatal zoonotic disease, predominantly transmitted through dog bites. With persistently high endemicity, India launched a National Action Plan in 2021 aligned with WHO's "Zero by 2030″ goal and dec...
Multidrug-resistant pathogens in UTIs: A concise review of epidemiology, diagnostics, and patent landscaping for precision healthcare [0.03%]
泌尿系统感染中多重耐药病原体的流行、诊断及精准医疗专利布局综述
Avani Bhimani,Tirth Chetankumar Bhatt,Munir Ibrahim et al.
Avani Bhimani et al.
UTIs are regarded as the second most prevalent global problem, with 150 to 250 million cases reported annually. Poor hygiene, anatomical abnormalities, and catheterization are the leading causes. Most UTI cases are caused by Escherichia col...
In vitro activity of essential antimicrobial agents, including ceftazidime/avibactam, imipenem/relebactam, and cefiderocol, against carbapenem-resistant Gram-negative bacteria primarily harboring the IMP-type carbapenemase gene in the Kinki region of Japan [0.03%]
日本近畿地区主要携带IMP型碳青霉烯酶基因的耐碳青霉烯类革兰阴性菌对常用抗菌药物包括头孢他啶/阿维巴坦、亚胺培南/雷利巴坦和_cefiderocol的体外活性研究
Tomokazu Kuchibiro,Tatsuya Nakamura,Makoto Niki et al.
Tomokazu Kuchibiro et al.
Objective: In cases of infections caused by multidrug-resistant Gram-negative bacilli (MRGNB), the efficacy of various antimicrobial agents may be limited due to antimicrobial resistance. This study evaluated the antimicr...
Longitudinally extensive myelitis: a rare parainfectious neurological complication of dengue [0.03%]
longitudinally延伸性脊髓炎:登革热的罕见并发病并发症
Andrés David Sastre-Martínez,Lina María Garzón-López,Raúl Andrés Vallejo-Serna et al.
Andrés David Sastre-Martínez et al.
Dengue fever, transmitted by Aedes aegypti, can cause neurological complications in up to 5 % of cases. Longitudinally extensive myelitis is a rare complication that affects three or more spinal segments and may occur in para-infectious or ...
Optimizing the diagnosis of pediatric group a streptococcus (GAS) pharyngitis: A comparative analysis of rapid antigen detection tests, molecular tests and global guidelines [0.03%]
儿童A组链球菌咽炎诊断优化:关于快速抗原检测、分子检测和全球指南的比较分析
Kenza Benboujida,Célestin Mairesse,Florence Adjavou et al.
Kenza Benboujida et al.
Group A Streptococcus (GAS) is a common cause of acute pharyngitis in children. Accurate and timely diagnosis is essential to guide appropriate antibiotic use and minimize unnecessary prescribing. While bacterial culture remains the gold st...
Prevalence of Mycoplasma genitalium in a Southern California patient population [0.03%]
加利福尼亚南部患者人群中的梅毒螺旋体感染率
Anh Tran,Alicia Amamoto,Monica Bates et al.
Anh Tran et al.
Mycoplasma genitalium as a cause of genitourinary sexually transmitted disease symptoms often goes underdiagnosed in many patient populations. We investigated a patient population in Southern California at high risk for Chlamydia trachomati...