Mechanistic study on the alleviation of oxidative stress-induced senescence in nucleus pulposus cells by CRT and the application of its ER-targeted derivative materials [0.03%]
CTRT和其靶向内质网的衍生物材料缓解氧化应激诱导髓核细胞衰老的作用机制研究
Junxian Hu,Zeyu Pang,Xiaoxiao Li et al.
Junxian Hu et al.
Oxidative stress-induced endoplasmic reticulum stress (ERS) plays a pivotal role in the senescence and degeneration of nucleus pulposus cells, and currently, no effective therapeutic options exist for intervertebral disc degeneration. The l...
Lipid metabolites profiles and allene oxide cyclase (AOC) expression pattern in Houttuynia cordata from diverse geographical regions: Unraveling the response to temperature variations [0.03%]
采自不同地理区域的鱼腥草中脂代谢产物及全部氧化环化酶(AOC)表达模式：对温度变化响应的解析
Lei Liu,Jiayi Yuan,Shuaiting Chen et al.
Lei Liu et al.
As an important medicinal and edible plant, Houttuynia cordata has rarely been studied for its lipid dynamics. This work identified lipid metabolites of H. cordata from five geographical regions across China, integrating transcriptome data ...
RAB1A promotes hepatitis B virus replication by enhancing PPARα-mediated viral transcription and inducing ULK1-mediated autophagy [0.03%]
RAB1A通过增强PPARα介导的病毒转录和诱导ULK1介导的自噬促进乙肝病毒复制
Chen Li,Zhenyu Zhao,Beinu Guo et al.
Chen Li et al.
Chronic hepatitis B virus (HBV) infection poses a significant risk for the development of hepatocellular carcinoma and remains a major public health challenge globally. RAB GTPases coordinate intracellular vesicle transport and regulate var...
Development of bioactive chitosan patch with ciprofloxacin loaded TiO₂ nanoparticles for wound healing application [0.03%]
一种负载环丙沙星的TiO₂纳米粒子的壳聚糖贴片的开发用于伤口护理
Samantha Raj Sah,D Prema,T Anusuya et al.
Samantha Raj Sah et al.
Different cellular mechanisms and functions drive the intricate process of skin wound healing. Because they interfere with the body's natural healing processes, microbial infections provide a serious obstacle to wound healing. To get over t...
Prediction of potential drug-resistant ALK mutations against fourth-generation inhibitors NVL-655 and TPX-0131 [0.03%]
预测NVL-655和TPX-0131药物对第四代ALK耐药突变的潜在效果
Fanyu Zhao,Wei Xia,Yuanqing Wang et al.
Fanyu Zhao et al.
Anaplastic lymphoma kinase (ALK) rearrangements have been identified as oncogenic drivers of multiple malignancies. Although at least three generations of ALK inhibitors have been developed, the occurrence of drug-resistant mutations remain...
Hydrogen bond-induced tea saponin incorporation with cellulose hydrogels enables accelerated acute wound healing [0.03%]
氢键诱导的茶皂苷与纤维素水凝胶结合促进急性伤口加速愈合
Yuansong Sun,Jinguo Xu,Qiang Zhou et al.
Yuansong Sun et al.
Tea saponin (TS), a pentacyclic triterpenoid extracted from tea trees, is a primary active ingredient of tea. They typically resist bacteria and promote acute wound healing. However, maintaining the long-lasting antibacterial effects of TS ...
Use of thermal coagulation of egg white protein for lignin removal from high-temperature hydrolysate to promote proliferation of Bifidobacterium adolescentis [0.03%]
高温水解液中热凝聚卵清蛋白去除木质素以促进青春双歧杆菌增殖的应用研究
Yuxin Yang,Yan Chen,Pengjing Lv et al.
Yuxin Yang et al.
In this study, the effectiveness of thermal coagulation of egg white proteins (EWPs-TC) procedure in removing lignin from high-temperature corn stalk hydrolysate (CSH) and its effect on Bifidobacterium adolescentis proliferation in treated ...
Application of tannic acid and Fe3+ crosslinking-enhanced chitosan films for wax apple (Syzygium samarangense) preservation [0.03%]
应用单宁酸和Fe3+交联增强的壳聚糖膜保鲜蜡苹果(Syzygium samarangense)
Junyan Guo,Zhengke Zhang,Gulden Goksen et al.
Junyan Guo et al.
This study examines the effects of edible chitosan coatings reinforced with tannic acid (TA) and ferric iron (Fe3+) double crosslinking on the quality of wax apples stored at room temperature. The effects of chitosan (CS) and CS/TA/Fe coati...
Pluronic F127-controlled synthesis of three-dimensional lignocellulose-derived carbon aerogels for high-efficiency removal of antibiotic pollutants [0.03%]
用于高效去除抗生素污染物的 pluronic f127 控制合成三维木质纤维素衍生碳气凝胶
Bin Sun,Minmin Zhao,Xiaojun Ma et al.
Bin Sun et al.
In this work, liquefied wood-derived lignocellulosic carbon aerogel (WCA-Fx), fabricated using Pluronic F127 as a soft template, was employed for the removal of tetracycline hydrochloride (TC) and sulfadiazine (SDZ) from aqueous solutions. ...
Lysozyme-modified nanocellulose for enhanced nucleation and antibacterial properties in advanced polylactide composites [0.03%]
透明质酸修饰的纳米纤维素增强聚乳酸复合材料的成核和抗菌性能
Aleksandra Grząbka-Zasadzińska,Wojciech Smułek,Natalia Kuleta et al.
Aleksandra Grząbka-Zasadzińska et al.
A novel two-step modification of nanocellulose using dicarboxylic acid followed by lysozyme functionalization was developed to enhance the performance of polylactide-based biocomposites. Different filler samples were synthesized under varyi...