Mechanistic study on the alleviation of oxidative stress-induced senescence in nucleus pulposus cells by CRT and the application of its ER-targeted derivative materials
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Oxidative stress-induced endoplasmic reticulum stress (ERS) plays a pivotal role in the senescence and degeneration of nucleus pulposus cells, and currently, no effective therapeutic options exist for intervertebral disc degeneration. The limited self-repair c... ...