Nanoquadruplex-driven hydrogen therapy: NIR-controlled release for targeted cancer ferroptosis [0.03%]
纳米四链体驱动的氢气疗法：近红外光控制释放用于癌症铁死亡的靶向治疗
Chunxue Dai,Yingjiao He,Hongyan Lu et al.
Chunxue Dai et al.
Hydrogen therapy as an emerging strategy for anticancer medicine is attracting attention. However, the limitations of effective hydrogen storage and release have hindered its development and application for hydrogen therapy. Herein, a high ...
A proactive cholinergic-like acidic fibroblast growth factor delivery system for efficient protein enrichment and native drug release in the central nervous system to promote repair of injured spinal cord [0.03%]
一种用于促进损伤脊髓修复的中枢神经系统高效蛋白质富集和原药释放的乙酰胆碱样酸性成纤维细胞生长因子主动递送系统
Dawei Jiang,Zhiyang Huang,Peng Dai et al.
Dawei Jiang et al.
Spinal cord injury (SCI) is a severe neurological trauma resulting in sensory deficits, impaired motor function, and compromised autonomic regulation. Acidic fibroblast growth factor (aFGF) with neuroprotective properties holds significant ...
Bioengineered human pre-vascularized microtissues reconstruct vascular niche and regenerative microenvironment to enhance functional skeletal muscle regeneration [0.03%]
生物工程化的人类预血管组织工程种子细胞重建血管生态位及功能肌再生微环境
Cheng Liang,Yu Gao,Jie Li et al.
Cheng Liang et al.
Skeletal muscle regeneration mediated by muscle satellite cells (MuSCs) is supported by the specific vascular niche containing endothelial cells, pericytes, and mesenchymal stem cells. Volumetric muscle loss (VML) severely disrupts the vasc...
Caiyan Zhao,Lin Li,Changrong Wang et al.
Caiyan Zhao et al.
Various nanoparticles have been developed as safe and effective carriers for mRNA delivery, aimed at preventing degradation. Despite numerous factors considered in nanoparticle design, the influence of mechanical elasticity on their prefere...
Multifunctional, enzyme/pH-responsive gelatin microspheres with aptamer-targeted antibacterial and ionic-mediated dual therapy for infected bone defects [0.03%]
多功能、酶/PH响应型明胶微球载抗菌药物实现 Aptamer靶向及离子介导的联合治疗促进感染性骨缺损修复
Rui Zhang,Yijing Stehle,Li Chen et al.
Rui Zhang et al.
The treatment of infectious bone defects requires simultaneous resolution of bacteria-associated antibiotic resistance, inflammatory microenvironment dysregulation, and impaired bone regeneration. Here, we developed an injectable, self-asse...
Ultrasound-driven manganese oxide nanocatalyts augment multipronged catalytic tumor therapies by unleashing mutually enhanced and sustained oxidative strom and ferroptosis [0.03%]
超声波驱动的锰氧化物纳米催化剂通过释放相互增强且持久的氧化风暴和铁死亡来增强多管齐下的催化肿瘤疗法
Mengying Hua,Ruohui Wu,Yanjia Lu et al.
Mengying Hua et al.
The catalytic strategies selectively eradicate tumors, but their efficacy is hindered by antioxidant defense mechanisms of tumor microenvironment (TME) and insufficient catalytic efficiency. Herein, we present a multifunctional manganese ox...
Yiqi Shi,Qi Wu,Ting Yang et al.
Yiqi Shi et al.
In situ gels with tumor-targeted therapy often struggle with precise spatiotemporal drug release, compromising their efficacy in complex and heterogenous tumors. Here, we present a temperature-activated in situ hydrogel (PTT-Br@mPEG-PLGA an...
A biomimetic multifunctional dressing based on stratum corneum microstructure: integrating antibacterial barrier and breathability for enhanced wound healing [0.03%]
一种基于角质层微观结构的仿生多功能敷料：兼具抗菌屏障和透气性的促伤口愈合敷料
Bo Liu,Li Yang,Heqing Yang et al.
Bo Liu et al.
The stratum corneum, which has a "brick-and-mortar" structure, serves as an impermeable barrier against pathogens while enabling gas and moisture exchange. Conventional wound dressings strive to reconcile these needs. They, often prioritize...
A multifunctional hydrogel promotes diabetic wound healing by remodeling iron balance and energy metabolism [0.03%]
一种多功能水凝胶通过重塑铁平衡和能量代谢促进糖尿病伤口愈合
Chen Jin,Yu-Zhe Lin,Ri-Yan Zhang et al.
Chen Jin et al.
Patients with diabetes often exhibit delayed wound healing, which is characterized by the endothelial cells dysfunction and excessive accumulation of free tissue iron. Ferroptosis, a form of regulated cell death driven by iron-dependent lip...
Corrigendum to 'CD44 and αV-integrins dual-targeting bimetallic nanozymes for lung adenocarcinoma therapy via NIR-enhanced ferroptosis/apoptosis' [Biomaterials 323 (2025) 123407] [0.03%]
“CD44和αV整合素双重靶向双金属纳米酶通过近红外增强的铁死亡/凋亡进行肺腺癌治疗”的勘误[Biomaterials 323 (2025) 123407]
Jingchuan He,Tingting Li,Xiaoqin Pan et al.
Jingchuan He et al.
Published Erratum
Biomaterials. 2025 Aug 21:123647. DOI:10.1016/j.biomaterials.2025.123647 2025