Development of zwitterionic hydrogel thin film coatings of cochlear implant electrode arrays that reduce intracochlear inflammation and electrode impedance [0.03%]
开发 cochlear 种植体电极阵列两性离子水凝胶薄膜涂层以减少耳蜗炎症和降低电极阻抗
Nir Ben-Shlomo,Adreann Peel,Christine Etler et al.
Nir Ben-Shlomo et al.
Cochlear implants (CIs) have revolutionized the treatment of sensorineural hearing loss, yet patient outcomes remain highly variable due to biological responses within the cochlea. A critical challenge is the foreign body response (FBR) tri...
The neural processing mode and development of emotional prosody in children with cochlear implants [0.03%]
人工耳蜗植入儿童情感语调的大脑加工模式及发展研究
Junsheng Hong,Tianyu Xin,Yuyang Wang et al.
Junsheng Hong et al.
Background: Prelingually deaf children with cochlear implants (CIs) receive a degraded representation of pitch and spectral cues that are critical for decoding emotional prosody. The early cortical processing modes and de...
Xinyue Zou,Jingyuan Chen,Biao Chen et al.
Xinyue Zou et al.
For cochlear implant (CI) users, differences in peripheral input patterns across ears may disrupt binaural fusion, thereby limiting binaural perception. The present study investigated factors affecting binaural fusion for speech segregation...
Intranasal gentamicin irrigation impacts number and morphology of auditory brainstem neurons [0.03%]
庆大霉素鼻腔冲洗影响听觉脑干神经元数量和形态学
LeAnn Haddad,Zachary Breeden,Sophia Franco et al.
LeAnn Haddad et al.
Gentamicin is an aminoglycoside antibiotic that broadly targets Gram-negative bacteria. Gentamicin exhibits ototoxic effects in both human subjects and animal models over several different routes of administration. While gentamicin is prima...
Auditory cortical forward masking effects in squirrel monkeys with unilateral noise-induced hearing loss [0.03%]
耳鸣动物模型的听皮层向前掩蔽效应研究
Steven W Cheung,Christoph E Schreiner
Steven W Cheung
Forward masking provides a sensitive measure of temporal and spectral processing in the auditory system and reflects underlying inhibitory mechanisms in auditory cortex. The present study examined how unilateral, noise-induced hearing loss ...
Cochlear histopathology in macaques after noise-induced temporary threshold shifts [0.03%]
恒河猴噪声性暂时性听阈移位后的耳蜗组织学改变
J A Mondul,C A Mackey,A N Conner et al.
J A Mondul et al.
Noise exposures causing transient hearing loss were previously considered benign. However, recent work has revealed that temporary noise-induced threshold shifts may be associated with long-lasting cochlear histopathology. One such effect i...
Acoustically functional 3D‑printed middle ear model for prosthesis development and otosurgical training [0.03%]
用于人工听小骨开发和耳科手术培训的可发声3D打印中耳模型
Sini Lähde,Anssi-Kalle Heikkinen,Jaan Seitsara et al.
Sini Lähde et al.
Background: Cadaver temporal bones are traditionally used in otosurgical training and research, but they have many limitations. The development of novel individualized middle ear prostheses requires easy and durable artif...
The development of inner ear gene therapy for DFNB9: From bench to bedside [0.03%]
从实验室到临床：DFNB9内耳基因治疗的研究进展
Meghan C Drummond,Wade Chien
Meghan C Drummond
Hearing loss is a significant health problem facing the world's population today. Approximately 3 in 1000 children born in the US are found to have hereditary hearing loss. Currently, hearing aids and cochlear implants represent the main tr...
Using non-invasive brain stimulation to promote auditory neuroplasticity in the setting of hearing intervention: A scoping review [0.03%]
用于听力干预的非侵入性脑刺激促进听觉神经可塑性的范畴性综述
Joshua M Wright,Lawrence Gregory Appelbaum,Sherri L Smith et al.
Joshua M Wright et al.
Cochlear implants (CI) have revolutionized our ability to treat severe sensorineural hearing loss (HL), yet there is substantial variability in speech perception outcomes. This may be due, in part, to the central nervous system's (CNS) resp...
Objective measures of sensory gating capacity do not predict the severity of misophonia symptoms [0.03%]
感官门控能力的客观衡量标准无法预测习得性神经过敏症状的严重程度
Yu K Du,Kate E Raymond,Facundo F Lodol et al.
Yu K Du et al.
Misophonia is characterized by intense negative emotional responses to specific trigger sounds. Given that repetitive sounds are frequently endorsed as triggers, we investigated whether impaired preattentive sensory gating contributes to mi...