Ethacrynic acid regulates gentamicin ototoxicity via the blood-labyrinth barrier [0.03%]
乙酰唑胺通过血液迷路屏障调节庆大霉素的耳毒性作用
Liling Li,Jingqian Tan,Dan Chen et al.
Liling Li et al.
Gentamicin (GM), a widely used aminoglycoside antibiotic, has its clinical utility significantly limited by ototoxicity, which may be further exacerbated by co-administered drugs. This study systematically investigated the ototoxic mechanis...
The impact of individual head-related transfer function augmentation on spatial release from masking [0.03%]
头相关传输函数的个体化增强对方向释放的影响研究
Nils Marggraf-Turley,Niels H Pontoppidan,Lorenzo Picinali
Nils Marggraf-Turley
Binaural hearing underpins effective communication in complex acoustic environments by increasing listeners' abilities to segregate concurrent sound sources. In certain conditions, interaural magnification of binaural cues has been shown to...
Xingqian Shen,Linlin Wang,Jing Li et al.
Xingqian Shen et al.
Purpose: To explore functional connectivity alterations in idiopathic tinnitus patients at the integrity, network, and edge levels through resting-state functional magnetic resonance imaging (rs-fMRI), and elucidating cen...
Auditory network plasticity in tinnitus across the adult lifespan: Insights from fMRI and structural connectivity [0.03%]
成人毕生耳鸣的听觉网络可塑性：来自fMRI和结构连接性的启示
Himanshu R Pandey,Amit Keshri,Neeraj Sinha et al.
Himanshu R Pandey et al.
Tinnitus, the perception of sound without an external source, is increasingly recognized as a disorder of large-scale brain networks rather than isolated auditory dysfunction. Aging introduces widespread neurobiological changes including co...
Central auditory and tinnitus consequences of pediatric chronic otitis media with effusion [0.03%]
儿童慢性分泌性中耳炎的中枢听觉及耳鸣后遗效应
Jacqueline E Weinstein,Jennifer Henderson Sabes,Lisa Rose et al.
Jacqueline E Weinstein et al.
Surgical intervention for pediatric chronic otitis media with effusion (COME) reverses hearing loss imposed by fluid in the middle ear space. Current recommendations are treatment implementation for bilateral COME, but only treatment consid...
MiRNA-634 promotes apoptosis in HEI-OC1 cells by regulating AK4 and AKT/mTOR signaling pathways [0.03%]
miR-634通过调节AK4和AKT/m TOR信号通路促进HEI-OC1细胞凋亡
Yida Wang,Yongzhi Liu
Yida Wang
Presbycusis, or age-related hearing loss (ARHL), is a complex condition characterized by the progressive accumulation of hearing loss associated with aging. Age-related deafness is caused by inner ear hair cell damage and loss. Previously, ...
Non-invasive testing to diagnose the underlying auditory pathology of hearing impairment [0.03%]
用于诊断听力受损潜在病因的无创检测技术
Neil J Ingham,Karen P Steel
Neil J Ingham
Of the three major classifications of inner ear pathology, sensory, neural and metabolic, it is relatively easy to distinguish a sensory pathology from a neural or inner hair cell pathology using current clinical tools. Deficiencies in both...
Ryan D Barnsley,John F Culling
Ryan D Barnsley
A bone-conduction hearing aid delivers sound to both cochleae by vibrating the skull. Consequently, bilateral fitting results in poor stereo separation. Here, we demonstrate improved stereo separation using crosstalk cancellation in unimpai...
Early hearing deprivation by silicon earplugs does not alter electrophysiological development of mouse dorsal cochlear nucleus fusiform neurons [0.03%]
硅耳塞早期听力剥夺不会改变小鼠背侧耳蜗核梭形神经元的电生理发育
Alan Eidi Sasaki,Nikollas Moreira Benites,Beatriz Rodrigues et al.
Alan Eidi Sasaki et al.
Rodent auditory brainstem neurons undergo substantial electrophysiological maturation during the postnatal period, spanning both pre- and post-hearing phases. These developmental adaptations support high-frequency, temporally precise neurot...
Editorial introduction: A collection of papers presented at the Symposium on ''The roots of auditory neuroscience in Spain: A tribute to Prof. Miguel A. Merchán'' [0.03%]
组稿人述要：“西班牙听觉神经科学的学术渊源——纪念梅尔昌教授”研讨会文集
Manuel S Malmierca,Stephen G Lomber,Eckhard Friauf
Manuel S Malmierca