A burden shared: The evolutionary case for studying human deafness in Drosophila [0.03%]
合力建设负担：果蝇研究人类耳聋的进化案例分析
Chonglin Guan,Muhammad Shaikh,Athanasia Warnecke et al.
Chonglin Guan et al.
Hearing impairment is the most prevalent sensory disease in humans and can have dramatic effects on the development, and preservation, of our cognitive abilities and social interactions. Currently 20 % of the world's population suffer from ...
Midbrain sensitivity to auditory motion studied with dichotic sweeps of broadband noise [0.03%]
宽带噪声二耳扫频刺激下听觉运动的中脑敏感性研究
Philip X Joris,Eric Verschooten
Philip X Joris
Many neurons in the central nucleus of the inferior colliculus (IC) show sensitivity to interaural time differences (ITDs), which is thought to be relayed from the brainstem. However, studies with interaural phase modulation of pure tones s...
Association of domain-general speed of information processing with spoken language outcomes in prelingually-deaf children with cochlear implants [0.03%]
人工耳蜗植入者的加工速度与先天性聋儿童的言语交流能力之间的关系研究
William G Kronenberger,Irina Castellanos,David B Pisoni
William G Kronenberger
Spoken language development after pediatric cochlear implantation requires rapid and efficient processing of novel, degraded auditory signals and linguistic information. These demands for rapid adaptation tax the information processing spee...
Exploring auditory temporal resolution and dichotic listening skills among individuals with type 2 diabetes mellitus [0.03%]
二型糖尿病患者的听觉时间分辨率和双耳听觉技能探究
Xu Jun Hu,Chi Chuen Lau,Rui Qi Ruan
Xu Jun Hu
The study aimed to explore the auditory temporal resolution and dichotic listening skills in patients with type 2 diabetes mellitus (T2DM) and identify associated health-related factors. Using a cross-sectional design, 87 adults with T2DM a...
Mfsd2a regulates the blood-labyrinth-barrier formation and function through tight junctions and transcytosis [0.03%]
Mfsd2a通过紧密连接和转胞吞作用调节血液-迷路屏障的形成与功能
Xiaoju Xu,Ke Xu,Fengqiu Chen et al.
Xiaoju Xu et al.
The Blood-Labyrinth Barrier (BLB) is pivotal for the maintenance of lymphatic homeostasis within the inner ear, yet the intricacies of its development and function are inadequately understood. The present investigation delves into the contr...
The role of hidden hearing loss in tinnitus: Insights from early markers of peripheral hearing damage [0.03%]
隐性听力损失在耳鸣中的作用：来自外周听觉损伤早期标志的见解
Pauline Devolder,Hannah Keppler,Sarineh Keshishzadeh et al.
Pauline Devolder et al.
Since the presence of tinnitus is not always associated with audiometric hearing loss, it has been hypothesized that hidden hearing loss may act as a potential trigger for increased central gain along the neural pathway leading to tinnitus ...
The impact of round window reinforcement on middle and inner ear mechanics with air and bone conduction stimulation [0.03%]
圆窗加固对空气和骨传导刺激下中耳和内耳力学的影响
Alexander Geerardyn,Irina Wils,Tristan Putzeys et al.
Alexander Geerardyn et al.
The round window (RW) membrane plays an important role in normal inner ear mechanics. Occlusion or reinforcement of the RW has been described in the context of congenital anomalies or after cochlear implantation and is applied as a surgical...
miR-130b-3p involved in the pathogenesis of age-related hearing loss via targeting PPARγ and autophagy [0.03%]
微RNA-130b-3p通过靶向过氧化物酶体增殖激活受体γ和自噬参与年龄相关性听力损失的发生发展
Juhong Zhang,Wenfang Sun,Shaojing Kuang et al.
Juhong Zhang et al.
The study focuses on the underlying regulatory mechanism of age-related hearing loss (ARHL), which results from autophagy dysregulation mediated by miR-130b-3p targeting PPARγ. We constructed miR-130b-3p knockout (antagomir) and PPARγ ove...
Tinnitus mechanisms and the need for an objective electrophysiological tinnitus test [0.03%]
耳鸣机制及客观电生理学检测的必要性
Emily M Fabrizio-Stover,Douglas L Oliver,Alice L Burghard
Emily M Fabrizio-Stover
Tinnitus, the perception of sound with no external auditory stimulus, is a complex, multifaceted, and potentially devastating disorder. Despite recent advances in our understanding of tinnitus, there are limited options for effective treatm...
Medial superior olive in the rat: Anatomy, sources of input and axonal projections [0.03%]
大鼠内侧膝状体橄榄核的解剖、输入和轴突投射
Héctor Rincón,Mario Gómez-Martínez,Marcelo Gómez-Álvarez et al.
Héctor Rincón et al.
Although rats and mice are among the preferred animal models for investigating many characteristics of auditory function, they are rarely used to study an essential aspect of binaural hearing: the ability of animals to localize the sources ...