miR-130b-3p involved in the pathogenesis of age-related hearing loss via targeting PPARγ and autophagy
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The study focuses on the underlying regulatory mechanism of age-related hearing loss (ARHL), which results from autophagy dysregulation mediated by miR-130b-3p targeting PPARγ. We constructed miR-130b-3p knockout (antagomir) and PPARγ over-expression (OE-PPA... ...
