An alternative pathway for delivery of power by outer hair cells to cochlear traveling waves [0.03%]
外毛细胞向耳蜗行波传递能量的替代路径
George Samaras,Julien Meaud
George Samaras
In vivo measurements show that the basilar membrane (BM) exhibits sharp frequency tuning and high sensitivity to low-level stimuli. This has led most cochlear theories to assume that outer hair cells (OHCs) amplify traveling waves by delive...
Atg7-dependent autophagy is indispensable for mice spiral ganglion neurons [0.03%]
ATG7依赖的自噬对小鼠耳螺旋神经节神经元是必不可少的
Chengke Sun,Xinyu Gao,Yuan Zhang et al.
Chengke Sun et al.
Atg7-dependent autophagy is critical for the long-term maintenance of the post-mitotic cells, yet its role in spiral ganglion neurons (SGNs) remains incompletely defined. Here, we conditionally ablated Atg7 in SGNs by generating Bhlhe22Cre/...
Dexamethasone abolishes intra-day fluctuations of electrode impedance in cochlear implant users [0.03%]
糖皮质激素消除人工耳蜗用户日内电极阻抗波动现象
Sarah Vormelcher,Maria Mitterberger-Vogt,Nils Prenzler et al.
Sarah Vormelcher et al.
Introduction: Dexamethasone-eluting cochlear implant (CI) electrode arrays aim to reduce mean electrode impedance and enhance stability. However, longitudinal data on intra-day impedance dynamics are lacking. This study c...
Spatial quantification of alterations in ossicular microarchitecture related to middle ear disease [0.03%]
听小骨微形态改变的空域量化与中耳疾病的关系研究
Margaux Schmeltz,Aleksandra Ivanovic,Anne Bonnin et al.
Margaux Schmeltz et al.
The human auditory ossicles -malleus, incus, and stapes- are critical for hearing, yet the middle ear that houses them is frequently affected by inflammatory conditions such as chronic otitis media with and without cholesteatoma, leading to...
Neural processing of speech in noise recognition in preschool children with different auditory processing abilities: a fNIRS study [0.03%]
不同听力处理能力学龄前儿童噪声下言语加工的神经机制研究：近红外成像技术探讨
Panting Liu,Wenmin Wang,Jia Zhou et al.
Panting Liu et al.
This study aims to investigate differences in brain oxyhemoglobin concentrations among preschool children with varying auditory processing (AP) abilities, as screened by the Preschool Auditory Processing Assessment Scale (PAPAS). The study ...
Development of zwitterionic hydrogel thin film coatings of cochlear implant electrode arrays that reduce intracochlear inflammation and electrode impedance [0.03%]
开发 cochlear 种植体电极阵列两性离子水凝胶薄膜涂层以减少耳蜗炎症和降低电极阻抗
Nir Ben-Shlomo,Adreann Peel,Christine Etler et al.
Nir Ben-Shlomo et al.
Cochlear implants (CIs) have revolutionized the treatment of sensorineural hearing loss, yet patient outcomes remain highly variable due to biological responses within the cochlea. A critical challenge is the foreign body response (FBR) tri...
The neural processing mode and development of emotional prosody in children with cochlear implants [0.03%]
人工耳蜗植入儿童情感语调的大脑加工模式及发展研究
Junsheng Hong,Tianyu Xin,Yuyang Wang et al.
Junsheng Hong et al.
Background: Prelingually deaf children with cochlear implants (CIs) receive a degraded representation of pitch and spectral cues that are critical for decoding emotional prosody. The early cortical processing modes and de...
Xinyue Zou,Jingyuan Chen,Biao Chen et al.
Xinyue Zou et al.
For cochlear implant (CI) users, differences in peripheral input patterns across ears may disrupt binaural fusion, thereby limiting binaural perception. The present study investigated factors affecting binaural fusion for speech segregation...
Intranasal gentamicin irrigation impacts number and morphology of auditory brainstem neurons [0.03%]
庆大霉素鼻腔冲洗影响听觉脑干神经元数量和形态学
LeAnn Haddad,Zachary Breeden,Sophia Franco et al.
LeAnn Haddad et al.
Gentamicin is an aminoglycoside antibiotic that broadly targets Gram-negative bacteria. Gentamicin exhibits ototoxic effects in both human subjects and animal models over several different routes of administration. While gentamicin is prima...
Auditory cortical forward masking effects in squirrel monkeys with unilateral noise-induced hearing loss [0.03%]
耳鸣动物模型的听皮层向前掩蔽效应研究
Steven W Cheung,Christoph E Schreiner
Steven W Cheung
Forward masking provides a sensitive measure of temporal and spectral processing in the auditory system and reflects underlying inhibitory mechanisms in auditory cortex. The present study examined how unilateral, noise-induced hearing loss ...