The effects and interactions of top-down influences on word recognition [0.03%]
自上而下的影响及其在词识别中交互作用的影响效应
Reuben Chaudhuri,Ryszard Auksztulewicz,Ruofan Wu et al.
Reuben Chaudhuri et al.
It is widely acknowledged that top-down influences such as our prior experiences, knowledge, and expectations influence the way in which we perceive information. However, little is known how different sources of top-down influences interact...
Hearing loss in a whirlin mouse mutant is not reversed by activating the Whrn gene [0.03%]
激活Whrn基因不能逆转旋眼鼠突变体的听力损失现象
Daniel R Pentland,Nina Treder,Shahd Najjar et al.
Daniel R Pentland et al.
WHRN gene mutations underlie several forms of deafness in humans and mice. It is not known whether WHRN-associated hearing loss can be reversed after its onset and we aimed to address this using a genetic approach. We show that a knockdown ...
Feasibility analysis of an implantable middle ear cavity pressure microphone [0.03%]
植入式中耳腔压电传感器的可行性分析
Lukas Prochazka,Adrian Dalbert,Christof Röösli et al.
Lukas Prochazka et al.
Introduction: Current cochlear implant systems do not yet provide recipients invisible, carefree, and 24/7 hearing. The main technical challenge for a totally implantable cochlear implant (TICI) system is the development ...
Qiang Li,Yuan Meng
Qiang Li
Hearing deprivation induces structural and functional reorganization in the brain, which compromises an individual's language processing capacity. As a tonal language, Mandarin Chinese requires fine-grained auditory processing for lexical t...
Functional near-infrared spectroscopy (fNIRS) biomarkers of tinnitus severity within tinnitus subtypes [0.03%]
耳鸣亚型中功能近红外光谱(tINRS)生物标志物预测耳鸣严重程度的研究
Mehrnaz Shoushtarian,Jamal Esmaelpoor,Michelle M G Bravo et al.
Mehrnaz Shoushtarian et al.
Tinnitus, the perception of sounds not present externally, can significantly impair quality of life. Currently there are no clinically available objective measures to enable monitoring of tinnitus-related changes in brain activity. Our prev...
Beyond suppression: Self-generation enhances perceived loudness and cortical responses to faint sounds [0.03%]
超越抑制：自我生成增强对微弱声音的感知响度和皮层反应
Carla Salgado,Stefanie Sturm,Marc Via et al.
Carla Salgado et al.
Perceptual and neural attenuation for self-generated (SG) sounds at clearly audible intensities is well established, yet recent work suggests a reversal at near-threshold levels, with SG sounds perceived as louder. Here we tested whether th...
Mineralocorticoid and glucocorticoid receptors in the mammalian inner ear: a scoping review [0.03%]
哺乳动物内耳的矿皮质激素受体和糖皮质激素受体：系统综述
Ewa Domarecka,Evi De Backer,Elsa Edlund et al.
Ewa Domarecka et al.
Mineralocorticoid (MR) and glucocorticoid (GR) receptors regulate stress and inflammation pathways relevant to hearing and balance, as well as corticosteroid treatments. However, translation to clinical outcomes remains inconsistent, likely...
Morgan Thienpont,F Deloche,S Keshishzadeh et al.
Morgan Thienpont et al.
Animal experiments have provided many insights on auditory function, notably in cases of sensorineural hearing loss (SNHL). However, it is not always clear how these findings translate to the human auditory system, especially in clinically ...
Bioinformatics Re-analysis of murine transcriptomic datasets identifies SASP and MAPK/NF-κB signaling pathways in noise-accelerated cochlear aging [0.03%]
生物信息学再分析小鼠转录组数据集，确定噪声加速耳蜗衰老中的SASP和MAPK/NF-κB信号通路
Guoping Zhang,Dandan Ren,Suju Wang
Guoping Zhang
Noise exposure is an important contributor to age-related hearing loss (ARHL) or presbycusis; however, the underlying mechanism remains elusive. This study re-analyzed two Mus musculus cochlear transcriptomic datasets on acoustic trauma fro...
Speech-in-noise difficulties in aminoglycoside ototoxicity reflects combined afferent and efferent dysfunction [0.03%]
氨基糖苷类药物耳毒性的噪音环境下言语理解困难反映了传入和传出功能障碍的共同作用
Lina Motlagh-Zadeh,Diala Izhiman,Chelsea M Blankenship et al.
Lina Motlagh-Zadeh et al.
Objectives: Patients with Cystic fibrosis (CF) often receive aminoglycosides (AGs) to manage recurrent pulmonary infections, placing them at risk for ototoxicity. Chronic AG use can lead to complex cochlear damage affecti...