Evaluation of the serum levels of CCL2, CCL3, and IL-29 after first and second administrations of the COVID-19 vaccine (Oxford-AstraZeneca) [0.03%]
评估COVID-19疫苗(Oxford-AstraZeneca)第一次和第二次接种后的血清CCL2、CCL3和IL-29水平
Zahra Bagheri-Hosseinabadi,Ayat Kaeidi,Mahdi Rezvani et al.
Zahra Bagheri-Hosseinabadi et al.
Background: Previous studies show that chemokines and cytokines play a very important role in eliciting an appropriate response against viruses. Vaccination causes inflammation in the person receiving the vaccine, accompa...
Hyperglycemia modulates M1/M2 macrophage polarization in chronic diabetic patients with pulmonary tuberculosis infection [0.03%]
高血糖调节慢性糖尿病患者肺结核感染中的M1 / M2巨噬细胞极化
Sudhasini Panda,Alisha Arora,Kalpana Luthra et al.
Sudhasini Panda et al.
Increased susceptibility to bacterial infections like tuberculosis (TB) is one of the complications of type 2 diabetes, however the underlying mechanisms remains poorly characterized. To explore how chronic hyperglycemia in diabetes affects...
Clinical relevance of ORCs in predicting prognosis and immunotherapy outcomes: A pan-cancer analysis [0.03%]
ORCs在预测预后和免疫治疗结果中的临床相关性：一项泛癌分析
Yajun Zhao,Jiangtao Wang,Xiaodong Liang et al.
Yajun Zhao et al.
Background: The origin recognition complex (ORC) consists of six subunits and mediates DNA replication by binding to its origin. Recent studies show that ORCs are closely related to various biological processes in tumors....
Engagement of CD300c by a novel monoclonal antibody induces the differentiation of monocytes to M1 macrophages [0.03%]
新型单克隆抗体通过结合CD300c促进单核细胞向M1型巨噬细胞的分化
Su In Lee,Haneul Kim,Chang Ki Lim et al.
Su In Lee et al.
Human CD300c is expressed on various immune or cancer cells and is a novel B7 family member, functioning as an activity modulator on immune cells. To elucidate the function of CD300c, we developed CL7, a human CD300c-specific monoclonal ant...
Toll-like receptor expression and functional behavior in platelets from patients with systemic lupus erythematosus [0.03%]
系统性红斑狼疮患者血小板中Toll样受体的表达及功能行为
María C Baroni Pietto,Ana C Glembotsky,Paola R Lev et al.
María C Baroni Pietto et al.
Background: Multiple blood cell abnormalities participate in the development of inflammation in systemic lupus erythematosus (SLE). Although platelets have been suggested as one of these contributors through the release o...
Deletion of mesencephalic astrocyte-derived neurotrophic factor delays and damages the development of white pulp in spleen [0.03%]
中脑星形细胞源性神经营养因子的缺失延缓并损害脾脏白色髓质的发育
Chengyue Zhou,Dan Han,Hui Fang et al.
Chengyue Zhou et al.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) stress-induced protein, and it has been reported that ER stress and unfolded protein response (UPR) are closely related to the immune system. The sp...
Significance of m6A in subtype identification, immunological evolution, and therapeutic sensitivity of RA [0.03%]
m6A在类风湿性关节炎亚型识别、免疫进化和治疗敏感性中的意义
Chenxi Ma,Jiasheng Wu,Hongwei Lei et al.
Chenxi Ma et al.
N6-methyladenosine (m6A) is one kind of important epigenetic modification pattern which is extensively involved in immune regulation. The development and progression of autoimmune diseases are closely related to immune dysregulation. Consid...
Levels of soluble TNF receptors (sTNFR1 and sTNFR2) increase with clinical worsening of patients and are related to COVID-19 mortality [0.03%]
可溶性肿瘤坏死因子受体(sTNFR1和sTNFR2)的水平随临床恶化而增加并与COVID-19死亡率相关
Melayne Rocha Aciole,Juliana Prado Gonçales,Patrícia Areias Feitosa Neves et al.
Melayne Rocha Aciole et al.
The present study aimed to inspect the serum levels of the soluble receptors, sTNFR1 and sTNFR2, in patients with COVID-19. The large production of inflammatory cytokines is an essential process in the pathogenesis of COVID-19. TNF is a mul...
Chlorella vulgaris extract and Imiquimod as new therapeutic targets for leishmaniasis: An immunological approach [0.03%]
铜绿扁藻提取物和咪喹莫特作为治疗利什曼病的新靶点：免疫学方法研究
Maria Gabriella Nunes de Melo,Isabelle Barreto da Silva Moreira Reino,Victor Vaitkevicius-Antão et al.
Maria Gabriella Nunes de Melo et al.
The therapeutic regimen for the treatment of American Tegumentary Leishmaniasis (ATL) is targeted at the death of the parasite; therefore, it is essential to develop a treatment that can act on the parasite, combined with the modulation of ...
Up-regulation of scleral C5b-9 and its regulation of the NLRP3 inflammasome in a form-deprivation myopia mouse model [0.03%]
形式剥夺性近视小鼠模型中巩膜C5b-9的上调及其对NLRP3炎性小体的调控作用研究
Kang Xiao,Zhengyu Chen,Songqing He et al.
Kang Xiao et al.
Background: Myopia has become a major public health problem worldwide. Although the involvement of the complement system in myopia progression has been reported, the underlying mechanism has not been well established. In ...