Clinical characteristics and risk factors of dyslipidemia in patients with rheumatoid arthritis [0.03%]
类风湿关节炎患者的脂代谢异常的临床特点及影响因素分析
Jia Liu,Yehua Jin,Sihan Wang et al.
Jia Liu et al.
Background: Dyslipidemia is highly prevalent in patients with rheumatoid arthritis (RA) and may be closely associated with systemic inflammation and disease activity. However, its clinical characteristics and predictive f...
Lymphocyte subpopulations in healthy Ukrainian men: local reference ranges, long temporal stability, and exercise-induced variability [0.03%]
健康乌克兰男性淋巴细胞亚群的局部参考范围、长期稳定性及运动引起的变异性能
Dariia Zabara,Iryna Kozeretska,Ivan Klapoushenko et al.
Dariia Zabara et al.
Reliable interpretation of lymphocyte immunophenotyping depends on population-specific reference ranges that account for demographic and environmental factors. However, such reference data are currently lacking for the Ukrainian population....
Immunological profile of acute Chagas disease patients infected via oral transmission and treated with Benznidazole: a two-year follow-up of immune responses [0.03%]
口服感染查加斯病患者苯硝唑治疗后的两年免疫学特征随访研究
Luciane de Freitas Firmino,Victor Vaitkevicius-Antão,Amanda Vasconcelos Nascimento et al.
Luciane de Freitas Firmino et al.
The state of Pernambuco, Brazil, reported its biggest outbreak of Acute Chagas disease (ACD) caused by oral transmission, in 2019. During the acute phase, timely access to treatment must be quick and performed in all cases, regardless of th...
Programmed death-ligand 1 correlates with acute influenza B virus infection [0.03%]
程序性死亡配体1与急性B型流感病毒感染相关
Hong Zhang,Ming Liu,Tongbao Feng et al.
Hong Zhang et al.
Programmed Death-Ligand 1 (PD-L1) has been proven to mediate various mechanisms to induce T-cell dysfunction in influenza A virus infection. However, whether PD-L1 similarly contributes to inflammatory responses during influenza B virus (IB...
Altered CD163 and tweak expression in dendritic cells is associated with cardiac function post-acute myocardial infarction [0.03%]
急性心肌梗死后树突状细胞中CD163和TWEAK表达的改变与心脏功能有关
Marín-Jáuregui Laura Sherell,Martínez-Shio Elena Berenice,Cárdenas-Hernández Ángel Martín et al.
Marín-Jáuregui Laura Sherell et al.
The activation of the innate immune system is crucial for myocardial recovery after acute myocardial infarction (AMI). Dendritic cells (DCs) and macrophages regulate inflammation and healing of the ischemic heart. This study aims to evaluat...
BCL3 drives an immunosuppressive tumor microenvironment in esophageal cancer by promoting M2 macrophage polarization via STAT3 activation [0.03%]
BCL3通过激活STAT3促进M2型巨噬细胞极化从而驱动食管癌免疫抑制性肿瘤微环境
Yushuai Geng,Haowen Ma,Minghang Liu et al.
Yushuai Geng et al.
Introduction: The progression of esophageal cancer is closely linked to the establishment of an immunosuppressive tumor microenvironment. Although B-cell leukemia/lymphoma 3 (BCL3) is dysregulated in various cancers, its ...
Clinical value of CTCs combined with serum tumor markers/inflammatory cytokines for the early diagnosis of non-small cell lung cancer [0.03%]
循环肿瘤细胞联合血清肿瘤标志物及炎症因子用于早期肺腺癌诊断的临床价值评估
Xiuxue Gu,Lingling Wan
Xiuxue Gu
Objective: This study investigates the clinical utility of circulating tumor cells (CTCs) in combination with serum tumor markers/inflammatory cytokines for the diagnosis of early-stage non-small cell lung cancer (NSCLC)....
Unmodified γδ T cells exhibit potent antitumor activity in hepatocellular carcinoma and are enhanced by PD-L1 blockade [0.03%]
未修饰的γδT细胞在肝癌中表现出强大的抗肿瘤活性，并可通过PD-L1抑制得到增强
Bo-Xiang Benjamin Zhang,Hong-Yi Lin,Hoang Yen Tran et al.
Bo-Xiang Benjamin Zhang et al.
Objective: Hepatocellular carcinoma (HCC) exhibits a profoundly immunosuppressive microenvironment that limits the efficacy of current immunotherapies. This study evaluated the antitumor activity of unmodified γδ T cell...
Differential astrocyte activation by Taenia solium antigens: Specific induction of IL-10 and IL-1β by Excretory/Secretory (ES) products [0.03%]
溶组织内阿米巴原虫抗元差异激活星形胶质细胞：ES产物特异性诱导IL-10和IL-1β
Kevin Gonzales,Jessy Condori,Guillermo Fernández et al.
Kevin Gonzales et al.
Background: Neurocysticercosis (NCC) is a parasitic infection of the central nervous system (CNS) caused by the larval form of Taenia solium. This disease provokes an inflammatory response that intensifies when the parasi...
Chlamydia psittaci inclusion membrane protein CPSIT_0844 elicits inflammatory IL-6 and IL-8 production in human monocytes via TLR2/TLR4 signaling pathways [0.03%]
奇异性沙眼衣原体包涵体膜蛋白CPSIT_0844通过TLR2/TLR4信号通路诱导人单核细胞产生炎性IL-6和IL-8
Xiaoliang Yan,Buwei Wang,Kang Zheng et al.
Xiaoliang Yan et al.
The respiratory disease caused by Chlamydia psittaci (C. psittaci) infection is often characterized by significant inflammation. In the present study, we demonstrated that the C. psittaci inclusion membrane protein CPSIT_0844 induced THP-1 ...