Rare earth element profiles and fractionation patterns in modern human dental enamel from Beijing, China [0.03%]
中国北京现代人牙齿釉质中的稀土元素剖面及分馏模式
Lisheng Zhao,Xiaoyu Hu,Guilin Han et al.
Lisheng Zhao et al.
Purpose: Rare earth element (REE) occurrence and fractionation in modern human dental enamel remain poorly characterized, limiting the use of enamel as a biomineral archive and for archaeological comparisons. This study c...
Preconception vs. postconception iodine supplementation: Effect on thyroglobulin decline in a Québec pregnancy cohort [0.03%]
妊娠前与妊娠后补碘对甲状腺球蛋白下降的影响——魁北克孕期队列研究结果
Jesse Bertinato,Philip Griffin,Marc Duciaume et al.
Jesse Bertinato et al.
Background: Meeting the increased iodine needs in pregnancy is vital, as deficiency, especially early on, can cause irreversible cognitive impairment of the infant. The American Thyroid Association advises that women who ...
Copper homeostasis and cuproptosis: New perspectives on the diagnosis and treatment of metabolic diseases [0.03%]
铜稳态与铜死亡：代谢性疾病的诊断和治疗新视角
Jing Chen,Chao Fang,Shiguo Tang et al.
Jing Chen et al.
Cuproptosis is a recently identified form of regulated cell death driven by the direct binding of Cu⁺ to the lipoyl moiety of mitochondrial tricarboxylic acid (TCA) cycle enzymes, leading to dihydrolipoamide S-acetyltransferase (DLAT) olig...
Targeting Ischemic stroke-related oxidative stress with metal nanoparticles: Mechanisms and therapeutic advances [0.03%]
金属纳米颗粒靶向缺血性脑卒中的氧化应激：机制和治疗进展
Ying-Ying Huang,Yi-Ning Zhao,Xia Bi
Ying-Ying Huang
Background: Ischemic stroke is a major cause of mortality and disability, largely driven by excessive reactive oxygen species (ROS) during ischemia-reperfusion injury. Current reperfusion therapies restore blood flow but ...
Exploring the association between genetic variation in selenoprotein genes (GPX1 and SELENOP) and biomarkers of selenium status in bipolar disorder: Evidence from a case-control study from the North African population [0.03%]
在北非人群双相障碍患者中探索硒蛋白基因(GPX1和SELENOP)多态性与硒状态生物标志物关联的病例对照研究证据
Ikram Chebieb,Nouria Dennouni Medjati,Majda Dali-Sahi et al.
Ikram Chebieb et al.
Selenium (Se) is an essential micronutrient that exerts an antioxidant role in the brain through selenoproteins; its dysregulation may be implicated in bipolar disorder (BD). This study investigates the association between Se status and BD ...
MicroRNA regulation by selenium nanoparticles: Mechanistic insights and translational perspectives in human disease [0.03%]
硒纳米粒子对微小核糖核酸的调节作用：机制见解及转化视角在人类疾病中的应用
Vlad Andrei Moldovan,Simona Daniela Cavalu,Monica Baia et al.
Vlad Andrei Moldovan et al.
Selenium nanoparticles (SeNPs) have emerged as physicochemically tunable nanoplatforms at the intersection of redox biology and post-transcriptional gene regulation. This review provides a systems-level synthesis of current evidence linking...
Ceruloplasmin and neurodegeneration: A link between copper dysregulation, iron imbalance, and neuronal damage [0.03%]
铜代谢异常、铁失衡与神经元损伤之间的关系：血清铜蓝蛋白的潜在作用
Deepika Kunwar,Jayant Kumar,Syed Afroz Ali et al.
Deepika Kunwar et al.
Ceruloplasmin (Cp) is a multifunctional multicopper oxidase principally produced in the liver and, to a lesser extent, in the central nervous system. It regulates iron homeostasis and oxidative balance, Cp oxidizes ferrous iron (Fe²⁺) to ...
Cisplatin-induced inflammatory liver injury via promoting free radicals' accumulation and Bax/Caspase-3 apoptotic signaling cascades: A possible mitigating role of high-purity selenium [0.03%]
顺铂诱导的炎症性肝损伤：通过促进自由基聚集和Bax/Caspase-3凋亡信号级联反应：高纯硒的可能缓解作用
Dina M Aboraya,Engy F Risha,Ayman El Baz et al.
Dina M Aboraya et al.
Background: Cisplatin is a prevalent anti-tumor agent despite its association with DNA damage, oxidative stress, myelosuppression, and hepatotoxicity, which may limit its use. The current study aims to assess the mitigati...
Temporal changes in fluoride concentrations in salivary compartments after dentifrice use and professional fluoride applications: Findings from a randomized clinical trial [0.03%]
牙膏和专业氟化物使用后唾液不同部分氟离子浓度的动态变化：随机临床试验结果
Evanildo Canuto Paz,Lyzia Vitória Mendes Rezende,Yarlla Rayanne Nogueira Dos Anjos Franco et al.
Evanildo Canuto Paz et al.
Background: This study evaluated temporal changes in fluoride concentrations in distinct salivary compartments, supernatant and sediment, up to 12 h after application of fluoridated products with different concentrations ...
Probabilistic assessment of cumulative heavy metal exposure from staple foods in a selenium-endemic area: Implications for dietary risk management [0.03%]
某硒缺乏地区主食中累积重金属暴露的概率评估及其膳食风险管的启示理意义
Shixi Zhang,Yangchun Han,Kun Zheng et al.
Shixi Zhang et al.
While selenium (Se) exposure in endemic poisoning areas has been extensively investigated, its co-occurrence with other heavy metals and the implications for integrated environmental health management remain insufficiently addressed. This s...