Zinc adjuvant treatment in SARS-CoV-2: A randomized clinical trial [0.03%]
锌作为SARS-CoV-2的佐剂治疗:一项随机临床试验
Silvia Gómez-Zorrilla,Elena Sendra,Juan Du et al.
Silvia Gómez-Zorrilla et al.
Introduction: Zinc is a trace element with a key role in immune function and has demonstrated antiviral and anti-inflammatory properties. Low plasma zinc levels have been associated with poor outcomes in COVID-19. This st...
Zinc levels in patients with lumbar disc herniation: A systematic review and meta-analysis [0.03%]
腰椎间盘突出症患者的锌水平:系统回顾和荟萃分析
Ayman M Zaroug,Mustafa Alkhawam,Monther M Hroub et al.
Ayman M Zaroug et al.
Introduction: Zinc is the most important trace element regarding matrix metalloproteinases (MMPs), which are the primary enzymes responsible for degeneration of the lumbar disc. Despite this, no connections have been made...
Nuclear factor E2 related factor 2 may alleviate liver injury by regulating iron overload and lipid peroxidation induced by chronic fluorosis [0.03%]
核因子E2相关因子2通过调节慢性氟中毒引起的铁过载和脂质过氧化可能减轻肝损伤
Xiao Xiao,Xi Tu,Na Wei et al.
Xiao Xiao et al.
The aim of the study is to explore the regulatory effect of nuclear factor erythroid 2-related factor 2 (Nrf2) on iron overload and lipid peroxidation in pathogenesis of liver injury induced by fluorosis. METHODS Liver function of the indiv...
Ferroptosis-targeting compounds modulate cancer cell cytotoxicity and migration: Insights from in vitro and in silico analyses [0.03%]
靶向铁死亡的小分子调节剂通过体内外研究证明其可以调节细胞毒性及迁移性
Kalimuthu Kalishwaralal,Prajakta Patil,Aniket Mali
Kalimuthu Kalishwaralal
Objective: Ferroptosis is an iron-dependent, non-apoptotic form of metabolic cell death driven by lipid peroxidation. While Glutathione Peroxidase 4 (GPX4) is the canonical ferroptosis suppressor, recent evidence highligh...
Neuroprotective effects of sodium molybdate in a beta-amyloid-induced rat model of Alzheimer's disease: An In Vivo preclinical study [0.03%]
硫酸钼钠对β淀粉样蛋白诱导的阿尔茨海默病大鼠模型的神经保护作用:一项体内临床前研究
Fatemeh Shahsavari,Akram Eidi,Fattah Sotoodehnejadnematalahi
Fatemeh Shahsavari
Background: Molybdenum, as a trace element, exhibits various pharmacological properties, including antioxidant, anti-inflammatory, and free radical-scavenging activities. This study aimed to evaluate the effects of sodium...
Improvement of well-being and fish fillet nutrient value of a vulnerable minor carp, Puntius sarana (Hamilton, 1822): A result of incorporating Fe trace element in diet through α-Fe2O3 nanoparticles as dietary supplements [0.03%]
α-Fe2O3纳米粒子作为鱼饲料添加剂对濒危鲤鱼(Puntius sarana)福利和营养价值的影响研究
Sampa Mondal,Nilanjana Chatterjee,Baibaswata Bhattacharjee
Sampa Mondal
Iron oxide (α-Fe2O3) nanoparticles (NPs) of different sizes are synthesized using a simple wet chemical method and are used as dietary supplements at rates of zero (control), 1, 2, 3, and 4 g/kg diet throughout the year in Puntius sarana t...
Deciphering the impact of essential elements on spermatozoa quality and seminal protein integrity- an in vitro and in silico study [0.03%]
解码必需元素对精子质量和精液蛋白质完整性影响的体内和体外研究
Parameswari R,Jesu Jaya Sudan R,Lesitha Jeeva Kumari J et al.
Parameswari R et al.
Background: Essential Elements (EEs) such as calcium, zinc, selenium, magnesium, copper, sodium, and potassium are essential for spermatogenesis. They maintain seminal proteins, especially semenogelin and sperm morphology...
Zn2 + alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU [0.03%]
锌离子通过MCU调节线粒体生物生成及动力学缓解H9c2细胞缺血再灌注损伤
Bingyu Wang,Bohan Xing,Luyao Huang et al.
Bingyu Wang et al.
Background: Zinc is an essential nutrient implicated in cardiovascular health. This study investigates whether Zn2+ protects H9c2 cells by regulating mitochondrial biogenesis, dynamics, and calcium homeostasis via the mit...
Impact of lead (Pb)-induced neurotoxicity on protein synthesis and cellular stress responses in LUHMES cells [0.03%]
铅诱导神经毒性的LUHMES细胞中的蛋白质合成和细胞应激反应的研究
Tsunehiko Hongen,Tomohiro Ito,Xian-Yang Qin et al.
Tsunehiko Hongen et al.
Exposure to lead (Pb) poses significant risks to human brain development. This study investigates the molecular mechanisms underlying Pb acetate-induced neurotoxicity in LUHMES cells, which represent a human fetal-derived dopaminergic neuro...
Neuroprotective efficacy of royal jelly and propolis against cadmium-induced dysregulation of neurogenesis and neurotransmitters in the brain of rats: Molecular mechanisms and ultrastructure investigations [0.03%]
royal jelly和propolis对镉诱导的大鼠脑神经发生和神经递质失调的神经保护功效:分子机制和超微结构研究
Norhan S El-Sayed,Eman M Omar,Esraa S Habiba et al.
Norhan S El-Sayed et al.
This study seeks to evaluate the neuroprotective efficacy of royal jelly (RJ) and propolis (P) against cadmium-induced dysregulation of neurogenesis and neurotransmitters in the brains of Wistar male rats and decipher implicated underlying ...