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Ceruloplasmin and neurodegeneration: A link between copper dysregulation, iron imbalance, and neuronal damage

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Ceruloplasmin (Cp) is a multifunctional multicopper oxidase principally produced in the liver and, to a lesser extent, in the central nervous system. It regulates iron homeostasis and oxidative balance, Cp oxidizes ferrous iron (Fe²⁺) to ferric iron (Fe³⁺)... ...