Six-gene-based prognostic model predicts overall survival in patients with uveal melanoma [0.03%]
六基因预后模型用于预测脉络膜黑色素瘤患者的总生存期
Qi Wan,Jing Tang,Jianqun Lu et al.
Qi Wan et al.
Background: Uveal melanoma (UM) is the most common primary intraocular tumor in adults, which has a high mortality rate and worse prognosis. Therefore, early potential molecular detection and prognostic evaluation seem mo...
MicroRNA-383-5p acts as a potential prognostic biomarker and an inhibitor of tumor cell proliferation, migration, and invasion in breast cancer [0.03%]
微小核糖核酸-383-5p可作为乳腺癌预后生物标志物及肿瘤细胞增殖、迁移和侵袭的抑制剂
Jingwei Zhang,Xia Kong,Qizhu Shi et al.
Jingwei Zhang et al.
Background: MicroRNAs (miRNAs) have been reported to serve as potential biomarkers in various cancer and play important roles in tumor progression. Object...
Textural features based enhanced contrast CT images predicts prognosis to concurrent chemoradiotherapy in stage III esophageal squamous cell cancer [0.03%]
基于纹理特征的同步放化疗术前CT图像增强对比预测三期食管鳞癌预后
Yuquan Xie,Qifeng Wang,Baorong Cao et al.
Yuquan Xie et al.
Introduction: To study the relationship between the tumor heterogeneity based on CT and overall survival (OS) in oesophageal squamous cell carcinoma treated with chemotherapy and radiation therapy (CRT). ...
Cecilia Pagaza-Straffon,Laurence A Marchat,Luis Herrera et al.
Cecilia Pagaza-Straffon et al.
Background: Recent studies indicate that serum from cancer patients contains auto-antibodies against oncoproteins so called tumor-associated antigens (TAAs), which represent promising diagnostic and prognostic biomarkers....
Predictive value of unmethylated RASSF1A on disease progression in non-small cell lung cancer patients receiving pemetrexed-based chemotherapy [0.03%]
未甲基化的RASSF1A对接受培美曲塞为基础的化疗的非小细胞肺癌患者疾病进展的预测价值
Qinfang Deng,Bo Su,Xianxiu Ji et al.
Qinfang Deng et al.
Background and objective: Chemotherapy remains the basis of the treatment of lung cancer, and screening biomarkers with predictive value for chemotherapy is of great interest. The present study focused on status of genes ...
Screening key lncRNAs with diagnostic and prognostic value for head and neck squamous cell carcinoma based on machine learning and mRNA-lncRNA co-expression network analysis [0.03%]
基于机器学习和mRNA-lncRNA共表达网络分析筛选头颈部鳞状细胞癌诊断及预后标志物lncRNA
Ying Hu,Geyang Guo,Junjun Li et al.
Ying Hu et al.
Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common type of cancer around the world. The aim of this study was to seek the long non-coding RNAs (lncRNAs) acting as diagnostic and prognosti...
Significance of NOTCH1 mutations détections in T-acute lymphoblastic leukemia patients [0.03%]
NOTCH1基因突变在T细胞急性淋巴细胞白血病中的意义检测
Salah Aref,Mohammed El Agdar,Osama Salama et al.
Salah Aref et al.
Background: This study aimed to determine the prevalence and clinical impact of neurogenic locus notch homolog protein 1 (NOTCH1) mutations among patients with T cell acute lymphoblastic leukemia (T-ALL). ...
The role of 18F-FDG PET/CT-based quantitative metabolic parameters in patients with ovarian clear cell carcinoma [0.03%]
18F-FDG PET/CT代谢参数在卵巢透明细胞癌患者中的作用研究
Shuang Ye,Shuai Liu,Shuling Zhou et al.
Shuang Ye et al.
Background: Ovarian clear cell carcinoma (CCC) is enriched in genes associated with glucose metabolism. Objective: To evaluate the 18F-...
Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis [0.03%]
Nrf2/Keap1通路与结直肠癌转移相关的线粒体功能改变
Liang-Che Chang,Chung-Wei Fan,Wen-Ko Tseng et al.
Liang-Che Chang et al.
Background: Both mitochondria and the Nrf2/Keap1 pathway are targets of cancer therapy. Reactive oxygen species released from mitochondria can activate Nrf2, and the Nrf2/Keap1 pathway affects glycolysis, oxidative phosph...
MicroRNA-105 plays an independent prognostic role in esophageal cancer and acts as an oncogene [0.03%]
microRNA-105在食管癌中具有独立的预后作用并作为致癌基因发挥作用
Ruixiang Gao,Zhen Wang,Qiang Liu et al.
Ruixiang Gao et al.
Background: Esophageal cancer is a common tumor with high mortality worldwide. In the present study, we aimed to investigate the prognostic significance and regulatory effects of miR-105 on cellular functions of esophagea...