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Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis

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Background: Both mitochondria and the Nrf2/Keap1 pathway are targets of cancer therapy. Reactive oxygen species released from mitochondria can activate Nrf2, and the Nrf2/Keap1 pathway affects glycolysis, oxidative phosphorylatio... ...