Gasdermin E: Bridging Pyroptosis, Immunity, and Disease Pathogenesis Toward Precision Intervention [0.03%]
Gasdermin E：连接焦亡、免疫和疾病病理向着精准干预发展
Ping Wang,Chuandan Wan,Yeqiong Xu et al.
Ping Wang et al.
Gasdermin E (GSDME), a pivotal executor of pyroptosis, has emerged as a central regulator of immune responses across a spectrum of diseases. Initially identified as a tumor suppressor and a deafness-associated gene (DFNA5), GSDME is now rec...
Identification of Moonlighting Proteins from Published Literature Using Natural Language Processing and AI [0.03%]
利用自然语言处理和人工智能从已发表文献中识别多功能蛋白
Dana Mary Varghese,Vishwas Kukreti,Ajay Kumar Verma et al.
Dana Mary Varghese et al.
Research publications on various aspects of functional genomics are constantly growing, providing an opportunity and challenge to mine for the information of interest, among them are the annotation of proteins into their specific functional...
Benjamin Widom (1930-2024) and the "∫" : Physical Chemist, Theorist, and Mentor [0.03%]
纪念本杰明·威德姆（1930−2024）和他的“∫”：物理化学家、理论学家和引路人
Prakash Narayan,Mahesh Narayan
Prakash Narayan
Comparison of Immunogenicity of Cood-Cotd, CfaB-st-CfaE, and Cssa-Cssb-ltb Chimeric Proteins and Their Chitosan Nanoparticles Against ETEC in an Animal Model [0.03%]
基于动物模型的ETEC联合疫苗及其壳聚糖纳米颗粒免疫原性比较研究
Behnam Zarei,Jafar Amani,Setareh Haghighat
Behnam Zarei
Enterotoxigenic Escherichia coli (ETEC) remains a major cause of diarrheal disease, and colonization factors together with enterotoxins are key targets for vaccine development. In this study, three ETEC-derived chimeric proteins, Cssa-Cssb-...
Integrated Experimental and In-Silico Analysis Indicates Melittin as a Modulator of IL-37a-Associated Networks in Neuroblastoma [0.03%]
整合实验和计算机模拟分析表明Melittin作为IL-37a相关网络在神经母细胞瘤中的调节因子
Berkay Ertan,Tugba Yalcinkaya,Elif Ercan et al.
Berkay Ertan et al.
Neuroinflammation is a key process that shapes tumor progression and cellular stress responses. While pro-inflammatory signaling components amplify these responses, IL-37a functions as an endogenous suppressor that limits inflammation. Meli...
Bruce E Bursten,Lawrence J Berliner
Bruce E Bursten
Published Erratum
The protein journal. 2026 Jun 4. DOI:10.1007/s10930-026-10337-5 2026
Screening of Small Peptide Against Ischemic Fatty-Acid Binding Protein (FABP) [0.03%]
小分子肽类化合物抑制缺血诱导脂肪酸结合蛋白(FABP)表达的筛选研究
Harshita Shand,Soumendu Patra,Thirumurthy Madhavan et al.
Harshita Shand et al.
A low-molecular-weight cytoplasmic protein called heart-type fatty acid-binding protein (H-FABP) is released by cardiac myocytes during an ischemic episode. The normal serum level of FABP is around 3.5 ± 0.4 ng/ml (males), 3.9 ± 0.4 ng/ml...
Bioactive Peptides: A Comprehensive Critical Review of Structure-Activity Relationships, Molecular Mechanisms, and Translational Limitations [0.03%]
生物活性肽：结构-活性关系、分子机制和转化限制的全面批判性评论
Navneet Kumar Prasad,Rashmi Saxena Pal,Yogendra Pal et al.
Navneet Kumar Prasad et al.
Bioactive peptides (BAPs) are short amino acid sequences released from precursor proteins through enzymatic hydrolysis, fermentation, or gastrointestinal digestion. Due to their diverse biological properties, BAPs have attracted significant...
Cloning, Expression, Purification and Biochemical Characterization of Novel Thermostable Subtilisin-like Serine Protease from Thermococcus onnurineus NA1 [0.03%]
热硫化叶菌NA1耐热碱性蛋白酶的克隆、表达、纯化及生物化学性质表征
Nafiu Usman Jiddah,Ya&#x;u Sabo Ajingi,Abubakar Sunusi Adam et al.
Nafiu Usman Jiddah et al.
The persistent rise in demand for biocatalysts in industries has prompted the exploration of novel enzymes. Proteases are very important class of enzymes with many industrial applications. However, majority of the reported proteases are fro...
Targeting oral squamous cell carcinoma with venom peptides: mechanisms, selectivity and translational potential [0.03%]
用毒液肽靶向口腔鳞状细胞癌：机制、选择性和转化潜能
Vanitha Marunganathan,Imran Uddin
Vanitha Marunganathan
Venom-derived peptides represent a promising new class of biotherapeutics for oral squamous cell carcinoma (OSCC), offering intrinsic tumor selectivity and multimodal anticancer activity that address key limitations of current chemoradiothe...