Expression, Purification, and Characterization of Recombinant Isocitrate Dehydrogenase (IDH) from Yarrowia lipolytica and its Application as a Protein Template for In Situ Synthesis of Gold Nanoparticles [0.03%]
来自Yarrowia lipolytica的异柠檬酸脱氢酶（IDH）的表达、纯化及表征及其作为蛋白质模板原位合成金纳米粒子的应用研究
Fatemeh Mojahedian,Elham Karimi,Farangis Ataei et al.
Fatemeh Mojahedian et al.
In this study, isocitrate dehydrogenase (IDH) was employed exclusively as a structural protein template for the synthesis of gold nanoparticles, rather than relying on its enzymatic catalytic function. The reduction of Au³⁺ to Au⁰ is acc...
Design of Plant Oil-Based Cationic Hydrogels for Protein Encapsulation and Controlled Delivery [0.03%]
基于植物油的阳离子水凝胶的设计用于蛋白质包封和控制释放
Asmaa Maaz,Gökhan Çaylı,Betül Giray et al.
Asmaa Maaz et al.
The development of sustainable multifunctional hydrogels with antibacterial activity and protein delivery capability is of great interest for biomedical applications. In this study, plant oil-derived cationic hydrogels were developed by UV-...
Taiji Oyama,Teruo Akuta,Tsutomu Arakawa
Taiji Oyama
Sodium dodecyl sulfate (SDS) is widely used in protein research. Micellar binding of SDS is accepted as a major mechanism of SDS binding to proteins. Here, we investigated SDS-protein interactions using near-UV circular dichroism (CD), fluo...
Tyrosinase Structural Perturbation and Functional Inhibition by an Ostrich-Derived Keratin-Diospyros lotus Nanobiocomposite: Biochemical Mechanism and Melanoma Cell Response [0.03%]
来源于鸵鸟角蛋白- Diospyros lotus纳米生物复合材料的酪氨酸酶结构扰动和功能抑制：生化机制及黑素瘤细胞响应
Marzieh Karimian Amroabadi,Azadeh Hekmat,Asghar Taheri-Kafrani et al.
Marzieh Karimian Amroabadi et al.
The aim of this study was to develop a bioactive keratin-based nanocomposite for modulation of tyrosinase structure and function. Keratin nanoparticles (KNPs) were synthesized from ostrich feathers and functionalized with Diospyros lotus le...
Encapsulation of Protein-Based Drug Carriers for Controlled Loading and Releasing Efficiency: A Review [0.03%]
基于蛋白质的药物载体的封装以控制负载和释放效率：综述
Mahadesh Chandro Mondal,H M Wasi Uddin,Sania Ashrafi et al.
Mahadesh Chandro Mondal et al.
Encapsulation of protein-based drug carriers represents a promising strategy for enhancing therapeutic efficiency by improving stability, bioavailability, and controlled release. Protein nanoparticles, due to their inherent biocompatibility...
G6PD: An Old Player with Multiple Emerging Roles from Cancer Progression to Metastasis and Chemoresistance [0.03%]
G6PD：一个在癌症进展、转移和化疗耐药性等方面扮演多重新兴角色的老玩家
Lubna Kanwal,Vishal Haer,Habiba Anum et al.
Lubna Kanwal et al.
Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of pentose phosphate pathway (PPP). It provides essential NADPH for redox balance and ribose-5-phosphate for nucleotide synthesis. Cancer and metastasis are linked to G6PD...
Gasdermin E: Bridging Pyroptosis, Immunity, and Disease Pathogenesis Toward Precision Intervention [0.03%]
Gasdermin E：连接焦亡、免疫和疾病病理向着精准干预发展
Ping Wang,Chuandan Wan,Yeqiong Xu et al.
Ping Wang et al.
Gasdermin E (GSDME), a pivotal executor of pyroptosis, has emerged as a central regulator of immune responses across a spectrum of diseases. Initially identified as a tumor suppressor and a deafness-associated gene (DFNA5), GSDME is now rec...
Identification of Moonlighting Proteins from Published Literature Using Natural Language Processing and AI [0.03%]
利用自然语言处理和人工智能从已发表文献中识别多功能蛋白
Dana Mary Varghese,Vishwas Kukreti,Ajay Kumar Verma et al.
Dana Mary Varghese et al.
Research publications on various aspects of functional genomics are constantly growing, providing an opportunity and challenge to mine for the information of interest, among them are the annotation of proteins into their specific functional...
Benjamin Widom (1930-2024) and the "∫" : Physical Chemist, Theorist, and Mentor [0.03%]
纪念本杰明·威德姆（1930−2024）和他的“∫”：物理化学家、理论学家和引路人
Prakash Narayan,Mahesh Narayan
Prakash Narayan
Comparison of Immunogenicity of Cood-Cotd, CfaB-st-CfaE, and Cssa-Cssb-ltb Chimeric Proteins and Their Chitosan Nanoparticles Against ETEC in an Animal Model [0.03%]
基于动物模型的ETEC联合疫苗及其壳聚糖纳米颗粒免疫原性比较研究
Behnam Zarei,Jafar Amani,Setareh Haghighat
Behnam Zarei
Enterotoxigenic Escherichia coli (ETEC) remains a major cause of diarrheal disease, and colonization factors together with enterotoxins are key targets for vaccine development. In this study, three ETEC-derived chimeric proteins, Cssa-Cssb-...