Novel Thermostable α-Amylase from Bacillus subtilis: Molecular Characterization, Optimization, and Docking-Based Substrate Profiling [0.03%]
一株来源于枯草芽孢杆菌的新型耐热α-淀粉酶的分子特性、优化及基于对接技术的底物谱分析
Shazeen Shoaib,Shumaila Naz,Iram Manzoor et al.
Shazeen Shoaib et al.
Bacterial alpha-amylases have diverse industrial applications in food, fermentation, and pharmaceuticals. This study focuses on the isolation and characterization of a novel alpha-amylase-producing bacterium through molecular and in silico ...
Pavel Levashov,Ilia Zaitsev,Sergei Zaitsev et al.
Pavel Levashov et al.
The review summarises the basic information on non-specific factors of mammals that potentially have antimicrobial action. A comparison of previously known factors with the latest literature data is carried out. The following peptide and pr...
Prakash Narayan,Lawrence J Berliner,Mahesh Narayan
Prakash Narayan
Structure, Mutation, Functional Domain Roles and Medical Implications of Glycerol Kinase [0.03%]
甘油激酶的结构、突变、功能区作用及其医学意义
Emmanuel Oluwadare Balogun,Israel Ogwuche Ogra,Uche Samuel Ndidi et al.
Emmanuel Oluwadare Balogun et al.
Glycerol kinase (GK) is a key part of glycerol metabolism. It connects the metabolic pathways for lipids and carbohydrates by phosphorylating glycerol to glycerol-3-phosphate in an ATP-dependent reaction. This is essential for maintaining c...
SARS-CoV-2 Spike Protein S2 Subunit: Recombinant Protein Expression Analysis, Purification, and Its Regulatory Effect on IGF-1R Expression [0.03%]
SARS-CoV-2刺突蛋白S2亚基:重组蛋白表达分析、纯化及其对IGF-1R表达的调控作用
Ekta Singh,Rajnish Kumar,Nishita Nishi et al.
Ekta Singh et al.
SARS-CoV-2 consists of the spike (S) protein which plays an important role in mediating the entry of virus into the host and it mainly consists of two subunits which are functionally different from each other. The first subunit S1, is invol...
Biophysical Characterization of an Engineered CD80 Variant for CTLA-4 Blockade in Cancer Immunotherapy [0.03%]
癌症免疫治疗中工程改造的CD80变异型表征及其阻断CTLA-4的作用机制
Zahra Hajihassan,Amir Hossein Mosayebi,Ramezan Ali Taheri et al.
Zahra Hajihassan et al.
Production Enhancement of Surface-Expressed D-hydantoinase and D-carbamoylase in E. Coli by Developing a Novel Coculture Process for the Efficient Biotransformation of D-p-hydroxyphenylglycine [0.03%]
通过开发新型共培养过程高效生物转化D-对羟基苯甘氨酸增强表面表达D-水杨酶和D-碳酰胺酶的产量
Fatemeh Poureini,Valiollah Babaeipour,Rasoul Khalilzadeh et al.
Fatemeh Poureini et al.
D-p-hydroxyphenyl glycine (D-PHPG) is a D-amino acid used as an intermediate in the synthesis of semi-synthetic antibiotics. It is synthesized from hydantoin derivatives through two sequential enzymatic reactions involving D-hydantoinase (D...
Bruce E Bursten,Lawrence J Berliner
Bruce E Bursten
Halved but Potent: Exploring the Inhibitory Property of Curcumin Derivatives Against Evolving SARS-CoV-2 Strains [0.03%]
半量却强力:姜黄素衍生物抑制新兴SARS-CoV-2毒株的探究
Atala Bihari Jena,Umesh Chandra Dash,Asim K Duttaroy
Atala Bihari Jena