Biochemical Characterization of the Staphylococcal Endolysin MV-L with Enhanced Activity Under Optimized Conditions and Effective Removal of MRSA from Surfaces and Biofilms [0.03%]
改良后MV-L溶菌酶高效裂解MRSA生物被膜及清除定植菌的研究
Felipe Neri Melo López,Lina Angélica Zermeño Cervantes,María Guadalupe González Alonso et al.
Felipe Neri Melo López et al.
Methicillin-resistant Staphylococcus aureus (MRSA) remains a major cause of difficult-to-treat infections, largely due to its multidrug resistance and capacity to form persistent biofilms on medical and industrial surfaces. Bacteriophage-de...
Physico-Chemical Properties of Silk Sericin Extracted by Hydrothermal Treatment [0.03%]
水热处理所得家蚕丝素蛋白的理化性质研究进展
I Sh Goyibnazarov,S S Yarmatov,B J Kholturayev et al.
I Sh Goyibnazarov et al.
In this work, studies were conducted to achieve the complete extraction of sericin from natural silk cocoons at temperatures of 100 °C and 110 °C for durations ranging 2-24 h without the use of chemical reagents. As a result, sericin samp...
Suguru Nishinami,Yoshiki Kihara,Teruo Akuta et al.
Suguru Nishinami et al.
Arginine is widely used in protein formulations to suppress protein aggregation and prolong the lifetime of the native, functional state which undergoes different stresses during storage, shipping and handling. However, arginine's different...
Structure-Based Drug Design Targeting the Substrate-Binding Pocket of MexB [0.03%]
基于结构的药物设计针对MexB的底物结合袋
Praveena Nanjan
Praveena Nanjan
The multidrug-resistant (MDR) phenotype of Pseudomonas aeruginosa poses a significant clinical challenge and frequently causes severe and potentially lethal infections. The activity of efflux proteins, which are membrane transporters that u...
Preparation and Evaluation of a Multi-Epitope Peptide for Assessing Immunotherapy of Colorectal Cancer in Vivo [0.03%]
用于评估体内结直肠癌免疫治疗的多抗原肽的制备及评价
Fatemeh Bahramibanan,Meysam Soleimani,Amir Taherkhani et al.
Fatemeh Bahramibanan et al.
The presence of tumor heterogeneity is a critical issue that restricts the success of targeted therapies and negatively impacts patient outcomes. Recent studies have concentrated on the development of multi-epitope peptides that exhibit con...
Soluble Expression of Recombinant Human Mitsugumin 53 in Escherichia coli NiCo21(DE3) [0.03%]
重组人源MG53在大肠杆菌NiCo21(DE3)中的可溶性表达
Kartika Sari Dewi,Winda Tasia,Dian Fitria Agustiyanti et al.
Kartika Sari Dewi et al.
Novel Thermostable α-Amylase from Bacillus subtilis: Molecular Characterization, Optimization, and Docking-Based Substrate Profiling [0.03%]
一株来源于枯草芽孢杆菌的新型耐热α-淀粉酶的分子特性、优化及基于对接技术的底物谱分析
Shazeen Shoaib,Shumaila Naz,Iram Manzoor et al.
Shazeen Shoaib et al.
Bacterial alpha-amylases have diverse industrial applications in food, fermentation, and pharmaceuticals. This study focuses on the isolation and characterization of a novel alpha-amylase-producing bacterium through molecular and in silico ...
Pavel Levashov,Ilia Zaitsev,Sergei Zaitsev et al.
Pavel Levashov et al.
The review summarises the basic information on non-specific factors of mammals that potentially have antimicrobial action. A comparison of previously known factors with the latest literature data is carried out. The following peptide and pr...
Prakash Narayan,Lawrence J Berliner,Mahesh Narayan
Prakash Narayan