G6PD: An Old Player with Multiple Emerging Roles from Cancer Progression to Metastasis and Chemoresistance
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Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of pentose phosphate pathway (PPP). It provides essential NADPH for redox balance and ribose-5-phosphate for nucleotide synthesis. Cancer and metastasis are linked to G6PD dysregulation, whic... ...
