Bridging miRNA Research with Clinical Applications in Cardiovascular Diseases: Advances in Delivery Systems and Therapeutic Strategies [0.03%]
心血管疾病中microRNA研究与临床应用的桥梁：递送系统和治疗策略的进展
Shiping He,Xiaolin Li
Shiping He
MicroRNAs (miRNAs) are integral to the regulation of gene expression pertinent to cardiovascular health, affecting various biological processes, such as cell adhesion, inflammation, and lipid metabolism. Certain miRNAs (miR-1, miR-133a, miR...
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer [0.03%]
靶向细胞核的治疗递送：癌症治疗的新概念
Deepak Kumar,Rishabha Malviya,Sathvik Belagodu Sridhar
Deepak Kumar
Exploring the Potential of Anacardic Acid, its Natural and Synthetic Analogues, and Nanoformulations as a Potential Antibacterial Agent, including Multidrug-Resistant Bacteria: A Comprehensive Review [0.03%]
探索安卡酸、其天然和合成类似物及纳米制剂作为抗菌剂（包括多药耐药菌）的潜力：综述性研究
Priyabrata Pattanayak,Ananya Pradhan
Priyabrata Pattanayak
The increasing rise of multidrug-resistant bacteria necessitates an urgent need for the discovery of novel antibacterial agents. Natural products have long been a source for identifying and isolating novel antibacterial agents. Anacardic ac...
Advancement in Gene Therapy for the Treatment of Parkinson's Disease: A Comprehensive Review [0.03%]
帕金森病基因治疗进展：综述论文
Mitul Lovras,Anjali Rana,Sonam Rani et al.
Mitul Lovras et al.
Parkinson's Disease (PD) is a neurological disease marked by the buildup of α-synuclein. The main symptom of the disease is the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Gene therapy may be a treatme...
Jiayi Xu,Liangwen Yan,Xinyan Li et al.
Jiayi Xu et al.
Stress granules (SGs) are membraneless cytoplasmic condensates formed through liquidliquid phase separation (LLPS) in response to diverse cellular stressors. These dynamic macromolecular complexes serve as critical signaling hubs that orche...
Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review [0.03%]
尼姆胶及其衍生物的理化性质、药物递送和组织工程应用：综述
Aayush Prakash,Rishabha Malviya,Sathvik Belagodu Sridhar et al.
Aayush Prakash et al.
Neem gum, a biocompatible and biodegradable polysaccharide, has broad applications in drug delivery and tissue engineering. Its hydrophilic and bioadhesive properties make it ideal for controlled drug release and scaffold fabrication. This ...
Advances in 4-Hydroxycoumarin Chemistry: Functionalization, Prominent 4-Hydroxycoumarin-based Therapeutics and Their Pharmacological Significance [0.03%]
4-羟基香豆素化学进展：官能团化、重要的4-羟基香豆素药物及其药理学意义
Sachu Sadan,Ponnusamy Shanmugam,Zeena S Pillai
Sachu Sadan
Background: This review discusses recent advances in 4-hydroxycoumarin (4-HC) and its derivatives, emphasising its promise as a versatile pharmacological agent with diverse bioactivities. ...
New Insights from Toxinology in Mammalian Reproduction: A Systematic Review [0.03%]
毒理学在哺乳动物繁殖研究中的新见解：系统性综述
Gabriel Acácio de Moura,Yasmin Mendes Rocha,João Pedro Viana Rodrigues et al.
Gabriel Acácio de Moura et al.
Introduction: Assisted reproductive techniques still have limitations regarding embryonic development and the achievement of clinical pregnancy. Animal venoms represent a biological library with the potential to trigger r...
Polysaccharide-Based Magnetic Nanoparticles in Brain Cancer: A Review on the Diagnostic and Therapeutic Potential of Ferumoxytol [0.03%]
基于多糖的磁性纳米颗粒在脑癌中的应用：对硫酸盐 Ferumoxytol 诊断和治疗潜力的综述
Christian Chapa González,Pamela Ocampo Valverde
Christian Chapa González
Polysaccharide-based iron oxide nanoparticles, particularly PSC-iron oxide nanoparticles, have emerged as promising agents for brain cancer diagnosis and therapy. Originally approved for anemia treatment, PSC-iron oxide nanoparticles levera...
A Comprehensive Analysis of the Therapeutic Potential of N-substituted Phenothiazine Derivatives in Medicinal Chemistry [0.03%]
药物化学中N取代的吩噻嗪衍生物治疗潜力的全面分析
Deepanjali Shukla,Iqbal Azad,Mohd Arsh Khan et al.
Deepanjali Shukla et al.
Phenothiazine and its N-substituted derivatives are pivotal in heterocyclic chemistry, serving as potential building blocks in chemical and pharmaceutical sciences. Over the past decade, extensive research has focused on the medicinal poten...