Mycoproteins and Beyond: Biotechnological Advances in Filamentous Fungal Biomass [0.03%]
肽类和超越：丝状真菌生物质的生物技术进展
Parwiz Niazi,Abdul Bari Hejran,Khaidarov Saken et al.
Parwiz Niazi et al.
The rapid growth of the global population has increased the demand for animal-based proteins, placing considerable pressure on land, feed resources, and space, ultimately making their production costly and environmentally taxing. Filamentou...
Multifunctional Therapeutic Potential of Phytocomplexes from Pterocarpus santalinus: A Review [0.03%]
圣檀木植物复合物的多功效治疗潜力：综述
Himanshu,Navin Kumar Tailor
Himanshu
Pterocarpus Santalinus: (red sandalwood) is a medicinal species native to the Eastern Ghats of South India, traditionally used in Ayurveda and Siddha for the treatment of inflammatory, gastrointestinal, dermatological, and metabolic disorde...
Ergül Mutlu Altundağ,Ayşe Tarbın Jannuzzi,Halil Eren Sakallı
Ergül Mutlu Altundağ
Conventional pharmacological treatments aim to achieve homeostasis via specific drug interactions within target cells. However, this often results in cellular damage to non-targeted cells, which clinically manifests as adverse side effects....
A Systematic Review On ERK/MAPK Signaling Circuit As The Critical Regulator In Chronic Wound Healing: Phytochemicals As Possible Modulators? [0.03%]
ERK/MAPK信号通路在慢性伤口愈合中的作用及其作为潜在调节因子的植物化学成分系统的文献复习
Krishnendu Adhikary,Saurav Barman,Riya Sarkar et al.
Krishnendu Adhikary et al.
Introduction: Wound healing is an important process in tissue regeneration and repair, during which events such as cell movement, proliferation, and tissue remodeling are keyfactor. Several pathological conditions, such a...
Multifunctional Capacity and Therapeutic Potential of Hydroxychavicol: An Allylarene Scaffold [0.03%]
羟基丁香酚的多功能性和治疗潜力：一种烯丙烷支架
Navin Kumar Tailor
Navin Kumar Tailor
The allyl-arene scaffold plays a crucial role in modern drug discovery and development owing to its remarkable structural versatility, broad bioactivity, and extensive pharmacological potential. Its significance is further strengthened by r...
Advances in Biomarkers for CAR-T Treatment Resistance in Diffuse Large B-Cell Lymphoma [0.03%]
CAR-T治疗难治性弥漫大B细胞淋巴瘤的生物标志物研究进展
Si Qi Yi,Lu Lu Chen,Li Xv et al.
Si Qi Yi et al.
Chimeric antigen receptor (CAR)-T cell therapy has made significant progress in treating hematologic tumors, particularly diffuse large B-cell lymphoma (DLBCL). However, over 50% of patients are resistant after CAR-T cell therapy for DLBCL,...
Nickel-based Enzymes and Compounds: Antimicrobial Potential, Biomedical Applications, and Toxicity Risks [0.03%]
镍基酶和化合物的抗菌潜力、生物医学应用及毒性风险
Sara Abdolmaleki,Alireza Aliabadi,Rasoul Motahari et al.
Sara Abdolmaleki et al.
Nickel-dependent enzymes are a class of metalloenzymes that require nickel as a key component for their biological activity. These enzymes are essential for various biochemical processes in certain organisms, particularly bacteria, archaea,...
Stimuli-responsive Lipid-drug Conjugates for Cancer Therapy: Mechanisms, Linker Chemistry, and Tumour Microenvironment Interactions [0.03%]
刺激响应型脂质-药物偶联物的癌症治疗：机制、连接子化学和肿瘤微环境相互作用
Saranya Rajanbabu,Esakkimuthukumar M,Divakar S et al.
Saranya Rajanbabu et al.
Lipid Drug Conjugates (LDCs) are the conjugates of drug molecules in which covalently bound lipids are attached, enhancing lipophilicity and altering other pharmaceutical properties. Overall, conjugates show improved oral bioavailability, t...
Trends in Pain Relief in Cancer Patients: Pharmacotherapy and Medical Device Therapy [0.03%]
癌症患者的止痛趋势：药物治疗与医疗器械治疗
Rohit Sharma,Mohsina Patwekar,Faheem Patwekar et al.
Rohit Sharma et al.
The landscape of cancer pain management has evolved significantly with advancements in pharmacological and medical device therapies, shifting focus from opioid reliance to a multimodal treatment approach. This strategy emphasizes the use of...
Artificial Intelligence-driven Drug Discovery: Transforming Pharmaceutical Innovation Through Computational Approaches [0.03%]
人工智能驱动的药物发现：通过计算方法变革制药创新
Affan Ahmad,Priyanshu Nema,Shashi Kiran Mishra et al.
Affan Ahmad et al.
The process of identifying and optimizing new drugs has long been recognized as expensive and complex. Many promising compounds have failed during the late stages of development, resulting in lost time and investment. Despite major advances...