[68Ga]Ga-DOTA-TOC Synthesis by a Cassette Developer System with [68Ga]GaCl3 from Cyclotron using Liquid Target: An Italian Experience [0.03%]
一种意大利经验：使用液体靶加速器生产镓-DOTA-TOC放射性药物
Michela Cossandi,Massimo Statuto,Giorgio Biasiotto et al.
Michela Cossandi et al.
Background: [68Ga-DOTA-D-Phe1-Tyr3]octreotide ([68Ga]Ga-DOTA-TOC) is a somatostatin analogue largely used in PET/CT applications for the detection of gastroenteropancreatic neuroendocrine tumors (GEP-NET). Initially, it w...
Evaluating the Effectiveness of Geant4 Software in Measuring the Damage Caused by Ti48 Ion Radiation on Nerve Cells, in Comparison to the Biophysical Model and Empirical Data [0.03%]
GEANT4软件测量Ti48离子辐射对神经细胞损伤有效性评估及其与生物物理模型和实测数据的对比研究
Habiballah Moradi,Eman Obeidavi,Akbar Aliasgharzadeh et al.
Habiballah Moradi et al.
Introduction: Presently, heavy particle ion radiation therapy is commonly utilized for the treatment of deep-seated malignancies, such as brain tumors. In addition to tumor treatment, these particles may negatively impact...
RNA Binding Proteins are Pivotal Regulators of Cancer Radioresistance and Potential Targets for Preventing Tumor Recurrence [0.03%]
RNA结合蛋白是调控癌症放射抗性及预防肿瘤复发的潜在治疗靶标的重要调节因子
Vasanth Kanth Thasma LoganathBabu,Srisri Satishkartik,Vanshikaa Karthikeyan et al.
Vasanth Kanth Thasma LoganathBabu et al.
RNA-binding proteins (RBPs) regulate gene expression at the post-transcriptional level and are important factors in cancer progression and response to various therapeutic strategies. Radioresistance, an obstacle caused due to various intrin...
Nuclear Nanomedicines: Utilization of Radiolabelling Strategies, Drug Formulation, Delivery, and Regulatory Aspects for Disease Management [0.03%]
核纳米医药：放射性药物标记策略、药剂配方、递送及疾病管理中的监管方面利用
Neeraj Gupta,Kalpana Nagpal
Neeraj Gupta
By integrating the sensitivity of nuclear medicine and the precision of nanotechnology, mankind can explore the very promising nuclear nanomedicine technology. Such integration enabled the imaging of biological processes at the molecular le...
Prediction of Recurrence using a Stacked Denoising Autoencoder and Multifaceted Feature Analysis of Pretreatment MRI in Patients with Nasopharyngeal Carcinoma [0.03%]
基于术前MRI的多模态特征分析及堆叠降噪自编码器预测鼻咽癌复发研究
Yibin Liu,Xianwen Wang,Jiongyi Li et al.
Yibin Liu et al.
Background: Strategies for predicting the recurrence of nasopharyngeal carcinoma need to be further development and validation. We developed a recurrence prediction model based on the fusion of multi-omics features from p...
The Central Composite Design and Artificial Neural Network Coupled with Genetic Algorithm in Optimization and Modeling of the Radiolabeling Process of 177Lu-hydroxyapatite as a Potential Radiosynovectomy Agent [0.03%]
中央复合设计和人工神经网络与遗传算法结合在优化和建模作为潜在放射合成剂的177Lu-羟基磷灰石的放射性标记过程中的应用
Sima Attar Nosrati,Maryam Salahinejad,Mohammad Reza Aboudzadeh et al.
Sima Attar Nosrati et al.
Background: A promising material used in radiation synovectomy of small joints is hydroxyapatite, labeled with 177Lu. During the design and production of radiopharmaceuticals, the condition of the radiolabeling process di...
A New Approach to Synthesizing Carbon-11-PBR28 and its Clinical Validation in ALS Patients [0.03%]
一种新的碳-11-PBR28合成方法及其在ALS患者中的临床验证
Pardeep Kumar,Aishwarya Kumar,Muddasu Keerthipriya et al.
Pardeep Kumar et al.
Background: Many studies have reported Translocator Protein (TSPO) overexpression in many neurological disorders. Carbon-11[11C]PBR28 is a widely used TSPO Positron Emission Tomography (PET) radiopharmaceutical. We have c...
Dilemma on Pancreatic Uncinate Process Uptake on Ga68-DOTATE PET/CT in Pediatric Neuroblastoma: Physiologic or Metastases? [0.03%]
生长抑素受体显像阳性的儿童神经母细胞瘤患者胰腺钩突区摄取增高：生理性摄取还是转移？
Nedim C M Gülaldi,Nadide Basak Gülleroglu,Selma Cakmakci et al.
Nedim C M Gülaldi et al.
Objective: The Ga68-DOTATATE PET/CT scan is an alternative imaging modality for the follow-up of children with neuroblastoma when the I123-MIBG scan was negative or weak. Somatostatin receptors (SSR) can be expressed in n...
Role of the p53/miR-34a/SIRT1 Feedback Loop in Metformin-induced Radiosensitivity of Colorectal Cancer Cells [0.03%]
二甲双胍通过p53/miR-34a/SIRT1反馈环增强结直肠癌放射敏感性的机制研究
Ensiyeh Bahadoran,Yazdan Zafari,Ali Homaei et al.
Ensiyeh Bahadoran et al.
Introduction: Metformin induces radiation sensitivity in cancer cells, including colorectal cancer cells; however, the exact molecular mechanisms underlying its radiosensitive effects are not yet known. In this study, we ...
Harnessing Radionuclides: Unveiling the Promising Role of Radiopharmaceuticals in Cancer Theranostics and Palliative Care [0.03%]
放射性同位素的利用：放射药物在癌症诊疗和姑息治疗中的作用展望
Mihai Cozmin,Ionut Iulian Lungu,Radu Cernei et al.
Mihai Cozmin et al.
Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow preci...