Characterization and functional analysis of FruR in Streptomyces lincolnensis: A pleiotropic regulator that links fructose metabolism to lincomycin biosynthesis [0.03%]
链霉菌FruR的表征及功能分析：一种多效性调控因子，将果糖代谢与林可霉素生物合成相联系
Yu Gao,Lei Chen,Zhicheng Zhang et al.
Yu Gao et al.
Lincomycin, a clinically important lincosamide antibiotic, is primarily produced by Streptomyces lincolnensis. This study demonstrated that fructose supplementation inhibits lincomycin biosynthesis. Gene function analysis and gene knockout ...
The secretory production of cutinase ICCG-A2 in Corynebacterium glutamicum using acetate as the sole carbon source [0.03%]
使用乙酸作为单一碳源在谷氨酸棒杆菌中分泌产生ICCG-A2切斯坦酶
Ziming Fan,Yu Zou,Yankun Yang et al.
Ziming Fan et al.
The utilization of edible biomass as feedstocks poses sustainability concerns, prompting the exploration of affordable alternative carbon sources. Acetate is a promising candidate due to its high availability and low cost. This study develo...
Immobilized laccase reactors for process intensification: kinetic comparison of batch and continuous-flow systems [0.03%]
用于过程强化的固定化漆酶反应器：批量和连续流系统动力学比较
Hiroshi Yamaguchi
Hiroshi Yamaguchi
Immobilized enzyme reactors operated under flow conditions are promising for process intensification in biocatalytic transformations; however, systematic kinetic comparisons between batch and flow configurations remain limited. Using acetos...
Thermal acclimation and nitrogen deprivation drive distinct transcriptomic reprogramming toward a shared lipid phenotype in the polar marine microalga Chlamydomonas malina RCC2488 [0.03%]
极地海洋微藻衣藻RCC2488在热习服和氮剥夺作用下转录组重塑趋同于脂质表型的机制研究
Lorena Yamileth Balón-Rosas,Irina Smolina,John Kyndt et al.
Lorena Yamileth Balón-Rosas et al.
Polar microalgae possess unique mechanisms that enable them to thrive in extreme environments; however, their molecular responses remain poorly explored in biotechnological contexts. This study presents the physiological and transcriptomic ...
Zn fortification and lipids modifications in mustard seeds treating with next gen plasma technology [0.03%]
次世代等离子技术处理芥子种子中的锌强化和脂质修饰
Mamunur Rashid,M R Talukder,Monzur Hossain
Mamunur Rashid
Mustard (Brassica alba L.) oil is widely used edible oil in the Indian subcontinent. Its use is restricted in many countries because of the presence of some unsaturated fatty acids (USFA) such as erucic acid that are responsible for myocard...
Preparation and characterization Polyethylene glycol @ Alginate-Chitosan Nanocomposite tailored for oral Insulin delivery [0.03%]
聚乙二醇@海藻酸钠-壳聚糖纳米复合材料的制备及表征用于口服胰岛素递送
Mirhane Mostafa Darwish,Wafaa M Khali,Ebtesam A Mohamad
Mirhane Mostafa Darwish
The incidence of diabetes is rising globally in large numbers due to genetic factors and dietary habits. Much research has gone into creating a safe and efficient particle drug delivery system for insulin. Polyethylene glycol @ Alginate-Chi...
Metabolic engineering of tomato fruits for production of raspberry ketone glycosides [0.03%]
代谢工程生产覆盆子酮糖苷
Takao Koeduka,Keisuke Yoshida,Yoko Iijima et al.
Takao Koeduka et al.
Raspberry ketone is a valuable aromatic compound that occurs only at trace levels in natural sources. In this study, transgenic tomato fruits expressing benzalacetone synthase (BAS) from Rheum palmatum and raspberry ketone/zingerone synthas...
Insight into the biotransformation pathway of oat phenolic in enzyme hydrolysis coupled with Monascus fermentation [0.03%]
燕麦酚酶解结合红曲发酵代谢路径研究
Haoqun Liu,Yao Li,Wenjing Xu et al.
Haoqun Liu et al.
Microbial fermentation and multi-enzyme systems can enhance the release and transformation of phenolic components in grains. This study constructed a system combining Monascus fermentation and multi-enzymatic hydrolysis to enrich phenolic c...
Leila Mwangi,Eric Warga,Jacob Elmer
Leila Mwangi
Gene therapy holds significant potential for treating genetic disorders, but the use of viral vectors is limited by factors such as immunogenicity, payload capacity, and high manufacturing costs. Nonviral gene delivery (NVGD) using plasmid ...
CRISPR/Cas9 system-mediated p21 knockout impairs the MITF signaling pathway [0.03%]
基于CRISPR/Cas9系统的p21敲除抑制MITF信号通路
Gyeong Hee Kim,Moon-Moo Kim
Gyeong Hee Kim
The CRISPR/Cas9 method facilitates targeted disruption of gene sequences, providing a reliable means to analyze gene-dependent regulatory pathways. This study aims to investigate melanogenesis in p21-knockout B16F1 cells generated by the CR...