Kyle Lethcoe,Robert O Ryan
Kyle Lethcoe
Myristic acid (14:0) is a relatively minor fatty acid in terms of abundance yet, in certain biological settings, it has a major impact. Although normally synthesized via the classical fatty acid biosynthesis pathway, in specific cases where...
Properties and biochemistry of phosphatidylcholine: diacylglycerol cholinephosphotransferase [0.03%]
卵磷脂的性质和生物化学：二酰基甘油-胆碱磷酸转移酶
Brandon A Ulch,Alyssa C Clews,Caroline A Reisiger et al.
Brandon A Ulch et al.
Plant oils, primarily composed of triacylglycerols (TAGs), are essential for both food and industrial applications. TAGs consist of three fatty acids esterified to a glycerol backbone, and their value and functionality are largely determine...
Physical and oxidative stability of lipid droplets (oleosomes) in seeds and emulsions [0.03%]
种子和乳状液中脂滴(油体)的物理稳定性和氧化稳定性
Marie Hennebelle,Lorenz Plankensteiner,Constantinos V Nikiforidis
Marie Hennebelle
Plants have developed a natural solution to a challenge that has long occupied emulsion scientists: how to stably maintain lipids in an aqueous environment while preventing physical and oxidative degradation. Lipid droplets (LDs) are abunda...
PLA2G4E in health and disease: Insights from omics and functional analyses [0.03%]
组学和功能分析揭示的 PLA2G4E 基因在健康与疾病中的作用
Maša Čater,Martin Šimon,Nicholas M Morton et al.
Maša Čater et al.
The phospholipase A2 (PLA2) enzyme superfamily has been extensively studied, but comprehensive reviews on cytosolic phospholipase A2 group IVE (PLA2G4E) remain scarce, limiting our understanding of its role in lipid metabolism and disease. ...
N-Acylethanolamines in cancer: mechanisms and therapeutic potential of lipid regulators of tumor behavior [0.03%]
脂肪调节剂在癌症中的作用机制及其治疗潜能
M F Nanì,M M Rinaldi,M Miraglia et al.
M F Nanì et al.
N-Acylethanolamines (NAEs) are endogenous bioactive lipids generated from membrane glycerophospholipids, with key members including arachidonoylethanolamide (anandamide, AEA), oleoylethanolamide (OEA), and palmitoylethanolamide (PEA). These...
Yukihiko Sugimoto,Shizu Aikawa,Tomoaki Inazumi et al.
Yukihiko Sugimoto et al.
Embryo implantation and subsequent decidualization are crucial processes for the establishment of a healthy pregnancy, but the molecular mechanisms underlying these processes remain unclear. Prostaglandins (PGs), which are synthesized from ...
Omega-3 polyunsaturated fatty acids in neurodegenerative disorders: Mixed designs = mixed results [0.03%]
欧米伽3多不饱和脂肪酸与神经退行性疾病：混合研究设计得出的结论莫衷一是
Simon C Dyall,Mélanie Plourde
Simon C Dyall
Epidemiological studies consistently show an elevated intake of fish and long-chain omega-3 polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), reduces the risk of developing neurodegener...
Homeocurvature: A new dimension of membrane adaptation to extreme environments [0.03%]
极端环境下的膜适应新维度：โฮモエカRVATURE
Jacob R Winnikoff,Itay Budin
Jacob R Winnikoff
Adaptation to abiotic factors is essential for life's radiation across the planet. Lipids, particularly sensitive to pressure and temperature (P and T), play a critical role in biochemical adaptation. In oceanic depths, lower temperatures a...
Different chains for different gains: How acyl chain diversity shapes S-acylated protein function [0.03%]
不同的脂肪链产生不同的功能效益：酰基链多样性如何影响蛋白的棕榈酰化功能
Carla Busquets Hernández,Alexandra Tsiotsia,Ludovico Pipitò et al.
Carla Busquets Hernández et al.
S-Acylation is a critical post-translational modification involving the attachment of fatty acyl chains to a large and diverse array of soluble and membrane proteins. The last two decades have witnessed a substantial acceleration in our und...
Targeting fatty acid-binding protein 4: A therapeutic intersection of obesity and cancer via lipid metabolism [0.03%]
靶向长链脂肪酸结合蛋白4：肥胖和癌症中的代谢治疗途径
Katarzyna Smolińska,Aleksandra Szopa,Piotr Dobrowolski et al.
Katarzyna Smolińska et al.
Fatty acid-binding protein 4 (FABP4) has emerged as a multifunctional regulator in cancer biology, linking dysregulated lipid metabolism, immune modulation, and tumor progression. Initially recognized for its role in fatty acid transport an...