5,6-epoxycholestanols metabolism and functions: Defining the epoxycholestanoid (EChA) family
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The oxidation of cholesterol at the Δ5 double bond generates 5,6-epoxycholestanols (5,6-ECs), which exist as two diastereoisomers, 5,6α-EC and 5,6β-EC. These metabolites define a distinct branch of sterol metabolism that integrates redox chemistry with rece... ...
