Are the 2023 ACR/EULAR classification criteria a step forward in the management of antiphospholipid syndrome? A literature-based and clinical practice appraisal [0.03%]
2023年ACR/EULAR分类标准在抗磷脂综合征管理中的进步：基于文献和临床实践的评估
Jaume Alijotas-Reig,Joana Marques-Soares,Enrique Esteve-Valverde et al.
Jaume Alijotas-Reig et al.
Antiphospholipid syndrome (APS) is an autoimmune disease (AID) without defined diagnostic criteria, but having classification criteria, as happens in most AID. Until 2023, we were using 2006 Sydney classification criteria. Although they had...
Environmental toxins and toxic metals in autoimmune diseases: Sex differences, hormonal influences, and immune dysregulation [0.03%]
环境毒素和有毒金属在自身免疫疾病中的作用：性别差异、激素影响和免疫功能紊乱
Geir Bjørklund,David R Wallace,Kimiya Kangarlou et al.
Geir Bjørklund et al.
Environmental toxins, including toxic metal(oid)s such as mercury, lead, cadmium, and arsenic, as well as endocrine-disrupting chemicals like bisphenol A and phthalates, play a critical role in the onset and progression of autoimmune diseas...
Extending the discussion: Cannabis based therapies in inflammatory bowel disease a letter to the editor [0.03%]
来信：大麻基疗flammatory bowel disease的治疗药物疗法讨论续论
Laxmikausthubha Yaratha,Anushka Deogaonkar,Marie L Borum
Laxmikausthubha Yaratha
Frank Verhoeven,Dalil Hannani,Céline Demougeot et al.
Frank Verhoeven et al.
Interleukin-33 (IL-33), an alarmin released upon tissue stress or damage, has gained increasing interest in the pathophysiology of inflammatory diseases such as spondyloarthritis (SpA). Acting through its receptor ST2, IL-33 contributes to ...
VE/VCO2 at ventilatory threshold and peak VO2 in CPET studies of patients with scleroderma-associated PAH: A systematic review and meta-analyses [0.03%]
系统性回顾与荟萃分析评估联合肺功能测定研究中硬皮病相关肺动脉高压患者通气阈值处VE/VCO2和峰值VO2的情况
Julie Better,Sylvie Leroy,Maarten K Ninaber et al.
Julie Better et al.
Context: Pulmonary arterial hypertension (PAH) is one of the leading causes of mortality in patients with systemic sclerosis (SSc). Cardiopulmonary exercise testing (CPET) has been studied to detect SSc-associated PAH. ...
Immune checkpoint inhibitor-induced inflammatory arthritis vs rheumatoid arthritis: A comparative review [0.03%]
免疫检查点抑制剂诱导的炎性关节炎与类风湿关节炎的比较分析
Iliopoulos Georgios,Sideridou Fani,Bogdanos Dmitrios et al.
Iliopoulos Georgios et al.
Immune checkpoint inhibitors (ICIs) have transformed the therapeutic landscape of oncology but are frequently accompanied by immune-related adverse events (irAEs). Among these, ICI-induced inflammatory arthritis (ICI-IA) has emerged as the ...
Sex-specific mechanisms in the pathogenesis and progression of chronic kidney disease [0.03%]
慢性肾脏疾病的发病机制和进展中的性别特异性机制
Guangtao Li,Zhiwei Xu,Hongxia Yang et al.
Guangtao Li et al.
Chronic kidney disease (CKD) is a growing global public health concern, marked by increasing prevalence and substantial economic burden. Notably, CKD demonstrates significant physiological sex differences. Epidemiological evidence indicates...
Association between weather conditions and rheumatoid arthritis: A systematic review and meta-analysis [0.03%]
天气条件与类风湿性关节炎关系的系统评价和meta分析研究
Chao Hu,Jingyi Wu,Yuanyuan Luo et al.
Chao Hu et al.
Objectives: Weather conditions have been suggested to influence the clinical manifestations of rheumatoid arthritis (RA), but current evidence remains inconsistent. This meta-analysis aimed to evaluate the association bet...
MTHFR polymorphisms in autoimmune diseases: Mechanistic and clinical perspectives [0.03%]
自身免疫性疾病中MTHFR多态性的机制和临床意义
Ting Sun,Yuxian Wu,Lingyun Kong et al.
Ting Sun et al.
The methylenetetrahydrofolate reductase (MTHFR) gene encodes a crucial enzyme in folate metabolism, serving as a central regulator of homocysteine homeostasis and one‑carbon metabolic pathways. This review synthesizes current evidence on t...
Impact of GLP-1 analogues on immune-mediated inflammatory diseases: A systematic review [0.03%]
GLP-1受体激动剂对免疫介导的炎症性疾病的影响：系统评价
Chhagan L Birda,Fadwa Ibrahim,Abhirup Chatterjee et al.
Chhagan L Birda et al.
Objective: Glucagon-like peptide-1 receptor agonists (GLP1RA) are believed to have anti-inflammatory properties apart from antidiabetic and anti-obesity effects. ...