Discrepancy between international guidelines and global laboratory practices in autoantibody testing for autoimmune hepatitis [0.03%]
自身免疫性肝炎自身抗体检测的国际指南与全球实验室实践之间的差异
Nicola Bizzaro,Dimitrios Bogdanos
Nicola Bizzaro
Therapeutic approaches in adults with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A review of current evidence [0.03%]
成人髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)的治疗策略：现有证据综述
Jakob Stögbauer,Victoria Schegerer,Clemens Klein et al.
Jakob Stögbauer et al.
Recent years have seen a considerable increase in knowledge pertaining to Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD). Nevertheless, a noteworthy degree of uncertainty remains within the neurological community, p...
Targeting age-related cell-free DNA for prevention, early diagnosis and treatment of rheumatoid arthritis [0.03%]
针对年龄相关的细胞游离DNA以预防、早期诊断和治疗类风湿性关节炎
Ning Ma,Yulin Xu,Dingqi Zhang et al.
Ning Ma et al.
Cell-free DNA (cf-DNA) refers to extracellular DNA fragments released during cell death, which have been observed to accumulate with advancing age. Elevated cf-DNA concentrations have been detected in the plasma and disease-affected tissues...
Autoantibody internalization in myositis skeletal muscle: Emerging evidence, mechanistic insights, and therapeutic relevance [0.03%]
多发性肌炎骨骼肌中自身抗体的内吞作用：新兴证据、机制见解和治疗相关性
Raphael A Kirou,Iago Pinal-Fernandez,Andrew L Mammen
Raphael A Kirou
The inflammatory myopathies-including dermatomyositis, immune-mediated necrotizing myopathy, anti-synthetase syndrome, and overlap myositis-are systemic autoimmune diseases characterized by myositis-specific and myositis-associated autoanti...
Extracellular vesicles in autoimmune diseases: Mechanistic underpinnings and precision medicine applications [0.03%]
自身免疫性疾病中胞外囊泡的作用及精准医疗应用：机制研究
Wenhui Mo,Yujie Zhang,Yu Zeng et al.
Wenhui Mo et al.
Autoimmune diseases constitute a collection of complex disorders characterized by abnormal immune responses directed against self-tissues. The pathogenesis of these diseases is strongly linked to the interaction of genetic predispositions a...
Sporadic late-onset nemaline myopathy (SLONM): Data from a case series and literature review of 144 patients [0.03%]
散发性晚发性肌内膜病（SLONM）：144例患者系列和文献回顾数据
Antonio Lauletta,Francesca Forcina,Gioia Merlonghi et al.
Antonio Lauletta et al.
Sporadic Late-Onset Nemaline Myopathy (SLONM) is an acquired myopathy presenting in adulthood with progressive proximal and axial muscle weakness. A substantial proportion of cases are associated with monoclonal gammopathy of undetermined s...
Regulated cell death in systemic lupus erythematosus: Key pathways and targeted therapies [0.03%]
系统性红斑狼疮中的细胞凋亡调控：关键通路与靶向治疗
Siying Deng,Ziwei Hu,Shaozhe Cai et al.
Siying Deng et al.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by pathological auto-antibody production and severe immune dysregulation. Dysfunction in regulated cell death (RCD) pathways is crucial in SLE development. Ab...
Senescent CD4+ T cells and autoimmune diseases: Mechanisms and therapeutic prospects [0.03%]
衰老的CD4+t细胞和自身免疫疾病：机制与治疗前景
Yue Hu,Liting He,Hai Long
Yue Hu
Senescent CD4⁺ T cells exhibit classical features of T-cell senescence-including telomere attrition, reduced proliferative capacity, and an upregulated senescence-associated secretory phenotype (SASP)-while also displaying unique character...
Jan Willem Cohen Tervaert
Jan Willem Cohen Tervaert
Many different drugs and/or vaccines may cause vasculitis which can be sometimes very severe. The clinical presentation varies from isolated skin vasculitis to multi-organ involvement with pulmonary-renal manifestations and/or cerebral vasc...
Ferritinophagy in inflammatory and autoimmune diseases: Mechanistic insights and therapeutic potentials [0.03%]
铁死亡与炎症和自身免疫疾病：机制见解与治疗潜力
Yi Wang,Yang Li,Jiani Jiang et al.
Yi Wang et al.
Ferritinophagy, a selective form of autophagy mediated by nuclear receptor coactivator 4 (NCOA4), degrades ferritin to regulate intracellular iron homeostasis and has emerged as an important process in inflammatory and autoimmune diseases. ...