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Antigen-specific tolerance therapies in type 1 diabetes: Disease-specific promises meet stage-specific challenges

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Type 1 diabetes (T1D) is a progressive autoimmune disease characterized by immune-mediated β-cell destruction, evolving from genetic susceptibility (stage 0) to presymptomatic autoimmunity (stages 1-2) and clinically symptomatic disease (stages 3-4). Immune a... ...