Proteomic analysis reveals differential responses to praziquantel in two Schistosoma mansoni strains with distinct phenotypes [0.03%]
蛋白质组分析揭示了两种表型不同的曼氏血吸虫对氯硝柳胺的不同反应
Marilia Bergamini Valentini,Tiago Manuel Fernandes Mendes,Fernanda Janku Cabral et al.
Marilia Bergamini Valentini et al.
Different Schistosoma mansoni strains may exhibit distinct phenotypes, which can influence parasite distribution, treatment outcomes, and control strategies. In this study, we conducted a label-free quantitative proteomic analysis to compar...
Can flukes cause cancer? Insight into molecular links between parasites and carcinogenesis [0.03%]
虫体可以致癌吗？寄生虫与癌症发生之间分子联系的洞察
Maria Paluch,Maja Cudzik,Aleksandra Kędra et al.
Maria Paluch et al.
Cancer deaths are increasing year by year worldwide. Many factors contribute to the development of cancer, including genetic and epigenetic factors, as well as environmental factors such as diet, physical activity, stimulants (tobacco, alco...
Sundas Afresham,Muhammad Kasib Khan,Muhammad Adnan Sabir Mughal et al.
Sundas Afresham et al.
Parasitic infections present a significant health risk to the public, affecting millions of people, particularly in underdeveloped and developing countries. In developing countries, these infections are also responsible for causing signific...
Targeted inhibition of human Tankyrase-1 (TNKS1) by ZT-5483 exhibited Anti-Parasitic activity in Toxoplasma gondii: An in silico-based, high-throughput virtual screen and in vitro approach [0.03%]
靶向抑制人Tankyrase-1(TNKS1)的ZT-5483在弓形虫中的抗寄生虫活性：基于计算机的高通量虚拟筛选和体外方法研究
Yasser Alraey
Yasser Alraey
Background and aim: Toxoplasmosis is considered one of the leading causes of mortality resulting from foodborne illness. This disease is caused by infection with the Toxoplasma gondii parasite. Given the serious side effe...
Stage-Dependent Expression and Vacuolar Localization of lasmodium berghei Chloroquine Resistance Transporter (CRT) [0.03%]
与发育阶段相关的氯喹抗性运输蛋白(CRT)的表达及定位于液泡膜上
Francois Korbmacher,Manuel Rauch,Sanketha Kenthirapalan et al.
Francois Korbmacher et al.
Plasmodium parasites encode a chloroquine resistance transporter (CRT), which is an integral membrane protein of the digestive vacuole and transports the antimalarial compound chloroquine out of this organelle. Here, we profiled the spatio-...
Loop-Mediated Isothermal Amplification (LAMP): A Promising Tool for Rapid, Point-of-Care Diagnosis of Parasitic Diseases in low-income countries [0.03%]
等温扩增（LAMP）技术在发展中国家寄生虫病现场快速诊断中的应用前景
Kevin Polpitiya,Madhavi Hewadikaram
Kevin Polpitiya
Parasitic diseases pose a major burden throughout the globe, especially in low-income countries, which are disproportionately affected due to factors such as overpopulation, vector-control challenges, financial difficulties, etc. Because ac...
Surface Molecules of Leishmania: From Virulence Determinants to Therapeutic and Vaccine Targets [0.03%]
利什曼原虫表面分子：从致病因子到治疗和疫苗靶点
Túlio Custódio Reis,Ana Clara Lunardi Yagi,Ana Laura Dias Ramos et al.
Túlio Custódio Reis et al.
Leishmaniasis is a group of neglected tropical diseases (NTDs) caused by protozoa of the genus Leishmania that affect vulnerable populations in tropical and subtropical regions. The disease manifests in cutaneous, mucocutaneous, and viscera...
Computational investigation of mutations in PfCRT and PfDHFR proteins for Emerging Resistance of Plasmodium falciparum to Antimalarial drugs [0.03%]
计算研究恶性疟原虫PfCRT和PfDHFR蛋白突变以应对抗疟药物的耐药性问题
Sushruta Ghosh,Deepesh Joshi,Chandra Sekar et al.
Sushruta Ghosh et al.
The emergence of multidrug resistance in Plasmodium falciparum poses a serious threat to antimalarial treatment, particularly with growing resistance to artemisinin-based combination therapies (ACTs) and partner drugs like piperaquine. Muta...
MBP - Journal Scope Update [0.03%]
MBA期刊范围更新
Christian Doerig,Richard McCulloch,Patrick Skelly et al.
Christian Doerig et al.
Decoding Leishmania in Equines: A Comparative Analysis of Molecular Targets [0.03%]
马体内利什曼原虫的分子靶标的比较分析研究报告
Muhammad Adnan Sabir Mughal,Muhammad Kasib Khan,He Lan et al.
Muhammad Adnan Sabir Mughal et al.
Parasitic diseases caused by Leishmania spp. create considerable health concerns in animals, resulting in a considerable financial impact. They causes a complex infection in equines, affecting weight gain, skin, liver, and spleen. To date, ...