Computational investigation of mutations in PfCRT and PfDHFR proteins for Emerging Resistance of Plasmodium falciparum to Antimalarial drugs
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The emergence of multidrug resistance in Plasmodium falciparum poses a serious threat to antimalarial treatment, particularly with growing resistance to artemisinin-based combination therapies (ACTs) and partner drugs like piperaquine. Mutations in key protein... ...
