The efficacy and accuracy of ribosomal RNA depletion methods in the parasitic nematode Strongyloides ratti [0.03%]
寄生线虫Strongyloides ratti中核糖体RNA脱耗方法的有效性和准确性
Mohammed Ahmed,Charmaine Bishop,Andrea Betancourt et al.
Mohammed Ahmed et al.
The depletion of ribosomal RNA (rRNA) is a critical step in RNA-sequence analyses, used to enhance the detection of non-rRNA molecules, such as messenger RNAs and non-coding RNAs. However, the efficiency and potential biases introduced by d...
Green-synthesised ZnO-Ag-CuO nanocomposites from Thymus vulgaris and their in vitro anticoccidial activity [0.03%]
牻牛儿醇合成立的氧化锌-银-氧化铜纳米复合材料及其体外抗球虫活性研究
Raghda R Qadir,Hamin J Mohammed,Samir M Hamad et al.
Raghda R Qadir et al.
Background: Coccidiosis is a significant parasitic disease affecting poultry, resulting in substantial economic losses due to its impact on growth, increased mortality, and compromised bird health. ...
CRISPR-Cas systems: Pioneering next-generation diagnostic tools for parasitic diseases [0.03%]
CRISPR-Cas系统：引领寄生虫疾病的下一代诊断工具
Rupesh Verma,Giridhari Das,H Manjunathachar th et al.
Rupesh Verma et al.
Parasitic diseases pose significant threats to both human and veterinary health, causing morbidity, mortality, and economic losses. Effective diagnostics are critical, yet conventional methods such as microscopy, serology, and polymerase ch...
Proteomic analysis reveals differential responses to praziquantel in two Schistosoma mansoni strains with distinct phenotypes [0.03%]
蛋白质组分析揭示了两种表型不同的曼氏血吸虫对氯硝柳胺的不同反应
Marilia Bergamini Valentini,Tiago Manuel Fernandes Mendes,Fernanda Janku Cabral et al.
Marilia Bergamini Valentini et al.
Different Schistosoma mansoni strains may exhibit distinct phenotypes, which can influence parasite distribution, treatment outcomes, and control strategies. In this study, we conducted a label-free quantitative proteomic analysis to compar...
Can flukes cause cancer? Insight into molecular links between parasites and carcinogenesis [0.03%]
虫体可以致癌吗？寄生虫与癌症发生之间分子联系的洞察
Maria Paluch,Maja Cudzik,Aleksandra Kędra et al.
Maria Paluch et al.
Cancer deaths are increasing year by year worldwide. Many factors contribute to the development of cancer, including genetic and epigenetic factors, as well as environmental factors such as diet, physical activity, stimulants (tobacco, alco...
Sundas Afresham,Muhammad Kasib Khan,Muhammad Adnan Sabir Mughal et al.
Sundas Afresham et al.
Parasitic infections present a significant health risk to the public, affecting millions of people, particularly in underdeveloped and developing countries. In developing countries, these infections are also responsible for causing signific...
Targeted inhibition of human Tankyrase-1 (TNKS1) by ZT-5483 exhibited Anti-Parasitic activity in Toxoplasma gondii: An in silico-based, high-throughput virtual screen and in vitro approach [0.03%]
靶向抑制人Tankyrase-1(TNKS1)的ZT-5483在弓形虫中的抗寄生虫活性：基于计算机的高通量虚拟筛选和体外方法研究
Yasser Alraey
Yasser Alraey
Background and aim: Toxoplasmosis is considered one of the leading causes of mortality resulting from foodborne illness. This disease is caused by infection with the Toxoplasma gondii parasite. Given the serious side effe...
Stage-Dependent Expression and Vacuolar Localization of lasmodium berghei Chloroquine Resistance Transporter (CRT) [0.03%]
与发育阶段相关的氯喹抗性运输蛋白(CRT)的表达及定位于液泡膜上
Francois Korbmacher,Manuel Rauch,Sanketha Kenthirapalan et al.
Francois Korbmacher et al.
Plasmodium parasites encode a chloroquine resistance transporter (CRT), which is an integral membrane protein of the digestive vacuole and transports the antimalarial compound chloroquine out of this organelle. Here, we profiled the spatio-...
Loop-Mediated Isothermal Amplification (LAMP): A Promising Tool for Rapid, Point-of-Care Diagnosis of Parasitic Diseases in low-income countries [0.03%]
等温扩增（LAMP）技术在发展中国家寄生虫病现场快速诊断中的应用前景
Kevin Polpitiya,Madhavi Hewadikaram
Kevin Polpitiya
Parasitic diseases pose a major burden throughout the globe, especially in low-income countries, which are disproportionately affected due to factors such as overpopulation, vector-control challenges, financial difficulties, etc. Because ac...
Surface Molecules of Leishmania: From Virulence Determinants to Therapeutic and Vaccine Targets [0.03%]
利什曼原虫表面分子：从致病因子到治疗和疫苗靶点
Túlio Custódio Reis,Ana Clara Lunardi Yagi,Ana Laura Dias Ramos et al.
Túlio Custódio Reis et al.
Leishmaniasis is a group of neglected tropical diseases (NTDs) caused by protozoa of the genus Leishmania that affect vulnerable populations in tropical and subtropical regions. The disease manifests in cutaneous, mucocutaneous, and viscera...