Environmental enrichment prevents depression-like behaviours induced by immune system activation in male mice [0.03%]
环境富养可防止激活的小鼠免疫系统引发的类似抑郁行为（英文：Environmental enrichment prevents depression-like behaviours induced by immune system activation in male mice）
Alexandre Kanashiro,Priscila Medeiros,Ana Carolina Medeiros et al.
Alexandre Kanashiro et al.
Depression is a debilitating psychiatric illness, and its etiology as well as resistance to current pharmacological treatments are increasingly associated with low-grade inflammation. Environmental enrichment (EE), a paradigm that combines ...
Artemisinin attenuates quinolinic acid-induced neurotoxicity by suppressing neuroinflammatory and apoptotic gene expression in rats [0.03%]
青蒿素通过抑制大鼠神经炎症和凋亡基因表达来缓解左旋喹啉酸诱导的神经毒性
Richmond Arthur,Uma Shanker,Manjinder Singh et al.
Richmond Arthur et al.
Neurotoxicity, characterised by the structural and functional disruption of the nervous system, remains a major contributor to the pathophysiology of neurodegenerative disorders. It is mostly caused by oxidative stress, excitotoxicity, mito...
Intermittent mild skin cooling stimulation inhibits pineal melatonin secretion in urethane-anesthetized rats [0.03%]
间断性皮肤轻度冷刺激可抑制尿烷麻醉大鼠松果体褪黑激素分泌
Nobuhiro Watanabe,Masamichi Moriya,Harumi Hotta
Nobuhiro Watanabe
Skin thermal stimulation can induce reflexive autonomic nerve responses and thereby influence endocrine functions. Melatonin, secreted from the pineal gland primarily under sympathetic control, exerts various physiological functions includi...
Short-term immobilization impairs pointing direction programming and early motor control processes [0.03%]
短期固定影响指向方向的编程和早期运动控制过程
C R Scotto,F R Danion,Y Blandin et al.
C R Scotto et al.
Short-term limb immobilization is a valuable method for studying the contribution of proprioception since it temporarily reduces sensory and motor inputs. While several studies have shown that immobilization impairs cognitive and sensorimot...
Limited effects of the REV-ERB agonist SR9009 after mouse spinal cord contusion: Reduced acute pathology with unaffected functional recovery and chronic white matter loss [0.03%]
SR9009脊髓损伤后作用有限：急性病理改变减轻但不影响功能恢复和慢性白质丢失
Lukasz P Slomnicki,Emily Hodges,Christine Armstrong et al.
Lukasz P Slomnicki et al.
The ligand-regulated transcription factors REV-ERBα/NR1D1 and REV-ERBβ/NR1D2 are promising neuroprotective targets. Systemic administration of the REV-ERB agonist SR9009 has been shown to reduce neuroinflammation, limit tissue loss, and e...
Expression of serotonin transporter (SERT) and receptors 5-HTR1A and 5-HTR2A in an animal model of hypothermia [0.03%]
低温动物模型中血清素转运蛋白(SERT)及其受体(5-HT1A和5-HT2A)表达量的变化
Andrei Negoiţă,Bogdan Amuzescu,Dan Florin Mihăilescu et al.
Andrei Negoiţă et al.
The role of anterior hypothalamus and preoptic area in thermoregulation has been studied since the late 19th century (Charles Richet 1884, Aronsohn&Sachs 1885), and thermosensitive neurons have been recorded in these areas. Numerous animal ...
Immunohistochemically-detected differential localization of CXCL14 in mouse cerebellum suggesting the presence of neuronal and glial forms of CXCL14 [0.03%]
免疫组化检测小鼠小脑中CXCL14的定位差异表明存在神经元型和胶质细胞型CXCL14
Hirohumi Suzuki,Toshiharu Yamamoto,Aya Hasegawa et al.
Hirohumi Suzuki et al.
In this study we compared staining profiles in mouse cerebellum, using two anti-CXCL14 antibodies, which we designated α and β. The α anti-CXCL14 antibody labeled Purkinje neurons; this was confirmed by double-immunofluorescence staining...
Kei Nakayama,Kotoko Suzuki,Yukiko Marunaka et al.
Kei Nakayama et al.
Importance of breastfeeding is well recognized, since it supports the survival of mammalian infants. The mammary papilla, a specialized skin region for breastfeeding, acts as a vital interface between mother and infant: perceiving the suckl...
Involvement of CXCR2 in chronic postsurgical pain occurrence through ERK/p38 activation [0.03%]
CXCR2通过ERK / p38活化参与慢性术后疼痛的发生
TianYu Ge,Xi Chen,Chang Liu et al.
TianYu Ge et al.
Chronic postsurgical pain (CPSP) is a global concern associated with significant health and economic issues for patients. We investigated the effects of C-X-C motif chemokine receptor 2 (CXCR2) related signal transduction mechanisms on CPSP...
Stress-type specific changes of VIP signaling in limbic regions of the rat brain [0.03%]
大鼠边缘叶脑区应激类型特异的VIP信号通路变化规律研究
Federico Ferro,Veronica Fontebasso,Magali Basille-Dugay et al.
Federico Ferro et al.
Vasoactive intestinal peptide (VIP) is a highly abundant neuropeptide in the central nervous system, implicated in the regulation of numerous behavioral and physiological functions, including the central stress response. Notably, VIP and it...