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Increased NMDA receptor GluN2A-type ionotropic signaling is sufficient to improve spatial memory in immature mice

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Spatial learning and memory are reliant on activation of N-methyl-D-aspartate receptors (NMDARs) at excitatory synapses in the hippocampus. NMDARs at immature synapses contain mostly GluN2B subunits while at mature synapses, more NMDARs contain GluN2A subunits... ...