Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design [0.03%]
针对同播PEDV和TGEV的下一代疫苗：整合核酸平台、黏膜递送和人工智能驱动的抗原设计
Xiaojun Hu,Zhenshan Wang,Shen Wang et al.
Xiaojun Hu et al.
Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) are causative agents of acute enteric diseases in pigs and have a high contagion potential. These coronaviruses (CoVs) impose substantial economic losses ...
High-Throughput Sequencings Revealed That Gut Microbiota Dysbiosis is Implicated in Gouty Arthritis of Red-Crowned Crane (Grus japonensis) [0.03%]
高通量测序揭示肠道微生物群失调与丹顶鹤痛风性关节炎有关
Hong Lin,Xiaoyang Zhu,Jianzhong Zhu et al.
Hong Lin et al.
The red-crowned crane (Grus japonensis) is one of the rarest cranes with a global population of less than 4000 individuals. The population of red-crowned crane could be influenced by health threats, including metabolic and infectious diseas...
Viral Distribution of Wild Boar Exposed to Low (Vaccine Candidate) and High Virulence African Swine Fever Virus Isolates: Immunohistochemical Characterization [0.03%]
低致病性和高致病性非洲猪瘟病毒分离株感染的野猪体内的病毒分布及免疫组化特征分析
Néstor Porras,Antonio Rodríguez-Bertos,Sandra Barroso-Arévalo et al.
Néstor Porras et al.
Although several biosecurity and control measures are currently in place to mitigate the African swine fever (ASF) epidemic, vaccination is being explored as a potential long-term strategy. However, standardized guidelines for evaluating th...
Celastrol Inhibits Porcine Epidemic Diarrhea Virus Replication by Promoting ROS-Mediated Apoptosis [0.03%]
Celastrol通过促进ROS介导的细胞凋亡抑制猪流行性腹泻病毒感染
Junhai Zhu,Kaifang Yang,Pengfei Zhang et al.
Junhai Zhu et al.
Porcine epidemic diarrhea virus (PEDV) causes acute, highly contagious enteric disease in pigs, leading to severe economic losses, particularly due to high mortality in suckling piglets. Currently, no specific antiviral drugs are available....
Molecular Characterization and Epidemiology of Lumpy Skin Disease Virus in Bhutan, 2023 [0.03%]
不丹2023年瘤皮病病毒分子特征和流行病学研究
Puspa M Sharma,Pelden Wangchuk,Dawa Tshering et al.
Puspa M Sharma et al.
Lumpy skin disease (LSD) is a disease of cattle and other ruminants caused by the LSD Virus (LSDV). LSD infections are characterized by high morbidity, low mortality, and significant economic impact. Initially endemic to Africa only, LSD ha...
Identification and Phylodynamic Analysis of the Siberian Subtype of Tick-Borne Encephalitis Virus in Tick-Bitten Patients From Northeastern China [0.03%]
中国东北蜱咬伤患者中的西伯利亚春夏季型蜱传脑炎病毒的鉴定及邻域动力学分析
Zhiwei Wei,Ziyan Liu,Yu Liu et al.
Zhiwei Wei et al.
Far Eastern (FE) tick-borne encephalitis virus (TBEV) was thought to be the only endemic subtype in northeastern China. However, in 2024, the Siberian (Sib) subtype of TBEV was found in ticks. This study investigates Sib-TBEV infection in t...
Nanoparticle-Based Antiviral Vaccines for Chickens: Recent Advances and Future Perspectives [0.03%]
基于纳米颗粒的禽类抗病毒疫苗： recent 近期进展和未来前景 perspectives perspectives
Peiyang Ding,Litong Xia,Shuoqi Dong
Peiyang Ding
Viral diseases in chickens, such as avian influenza, Newcastle disease, and infectious bronchitis, cause significant economic losses to the global chicken industry, while the cross-species transmission risks of avian influenza viruses (AIVs...
The Decade of Porcine Circovirus Type 2 (PCV2) in Thailand: Phylodynamic and Molecular Epidemiology [0.03%]
泰国猪圆环病毒二型(PCV2)的十年：系谱动力学和分子流行病学
Tepyuda Sritrakul,Narut Thanantong,Alongkot Boonsoongnern et al.
Tepyuda Sritrakul et al.
Porcine circovirus type 2 (PCV2) is a major swine pathogen causing significant economic losses in the swine industry worldwide. Continual monitoring of genetic and antigenic diversity is essential for the early detection of emerging variant...
RACK1 Associates With STING to Promote Type I Interferon Activation and Inhibit Pseudorabies Virus Infection [0.03%]
RACK1通过与STING互作促进I型干扰素活化并抑制伪狂犬病毒复制
Yixuan Li,Yiyu Liu,Yu Dai et al.
Yixuan Li et al.
Pseudorabies virus (PRV), the causative agent of Aujeszky's disease, leads to great economic losses on swine production worldwide. Receptor of activated protein kinase C 1 (RACK1) is initially known as a receptor for protein kinase C, and r...
Emerging Trichomonad Infections in Companion Animals: Rapid Visual Detection of Pentatrichomonas hominis and Tritrichomonas foetus Using an RPA-CRISPR/Cas12a Assay [0.03%]
伴侣动物中隐孢子虫感染的新兴病原体：使用RPA-CRISPR / Cas12a测定法快速视觉检测Pentatrichomonas hominis和Tritrichomonas foetus
Yang Zou,Zhi-Wen Yao,Tao Xiao et al.
Yang Zou et al.
Pentatrichomonas hominis (P. hominis) and Tritrichomonas foetus (T. foetus) are prevalent intestinal protozoa. P. hominis is associated with chronic diarrhea in humans and animals, whereas T. foetus causes gastrointestinal disease in compan...