Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol-Lowering Compound Library [0.03%]
从降胆固醇化合物库中发现抗猪流行性腹泻病毒新药"Cetaben"
Yaqin Li,Panpan Qin,Kaiqi Zhang et al.
Yaqin Li et al.
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such...
Selective Autophagy Mediated by Protein Ubiquitination in Major Prevalent Zoonoses [0.03%]
由蛋白质泛素化介导的选择性自噬在主要人畜共患病中的作用
Chi Meng,Fengyuan Jiao,Gengxu Zhou et al.
Chi Meng et al.
Zoonotic diseases not only cause great harm to animal health but also involve the development of animal husbandry, which in turn endangers human life and health and public health safety. Protein ubiquitination and autophagy are important wa...
Subtle Genetic Shifts of African Swine Fever Virus Among Vietnamese Domestic Swine Following Live-Attenuated Vaccine Commercialization [0.03%]
越南商业化减毒活疫苗后家养猪群体非洲猪瘟病毒的微妙基因变化
Thanh Che Nguyen,Phakawat Tantitaveewattana,Nakarin Pamornchainavakul et al.
Thanh Che Nguyen et al.
Since its first incursion in 2019, African swine fever (ASF) has remained a constant threat to the Vietnamese swine industry. The nationwide commercialization and implementation of live-attenuated vaccines (LAVs), alongside depopulation-rep...
Host Community Traits Driving Crimean-Congo Hemorrhagic Fever Virus Maintenance in Iberian Ecosystems [0.03%]
伊比利亚生态系统中维持克里米亚-刚果出血热病毒的宿主社区特征
Patrícia Xavier,Alberto Perelló,Víctor Luque-Castro et al.
Patrícia Xavier et al.
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonosis of significant public health concern, maintained in complex multihost systems shaped by ecological, climatic, and anthropogenic drivers. In the Iberian Peninsula, changing land...
Candida albicans in Faeces of Migratory Geese Can Persist in Agricultural Soils: One-Health Implications for Grazing Livestock [0.03%]
一项关于候鸟粪便中白色念珠菌可以持续存在于农业土壤中的研究：对放牧家畜的“同一个健康”的启示
Luke Woodford,Craig J Engelbrecht,Maiken Skov et al.
Luke Woodford et al.
The World Health Organization has classified five species of Candida as pathogens of critical concern on its recent 'Fungal Pathogen Priority List'. Candida albicans is the most common species aetiologically associated with human and animal...
Transboundary Animal Diseases Associated With Cross-Border Camel Movement. A Systematic Review and Meta-Analysis [0.03%]
跨境骆驼迁移相关的跨边界动物疾病——系统评价和荟萃分析
Alex A Adikwu,Theophilus I Emeto,Paul F Horwood et al.
Alex A Adikwu et al.
Transboundary animal diseases (TADs) are contagious diseases that significantly impact livestock health, public health and economic stability. In regions with frequent cross-border trade and transhumance involving camels, particularly the M...
Comparative Evaluation of ELISA Tests for Bovine Tuberculosis Detection: Implications for Improved Disease Control [0.03%]
用于检测牛结核病的ELISA试验的比较评估：改善疾病控制的启示
Carlos Eugênio S Vidal,Ingrid Ieda F Souza,Carlos Alberto N Ramos et al.
Carlos Eugênio S Vidal et al.
Accurate diagnosis of bovine tuberculosis (bTB) remains a critical challenge for disease control and eradication programs. While cell-mediated immune (CMI) response tests such as the comparative cervical intradermal tuberculin test (CCITT) ...
Rapid and Visual Detection of Muscovy Duck Reovirus Using a Reverse Transcription Recombinase-Aided Amplification Assay in a Lyophilized Format for Point-of-Care Applications [0.03%]
用于床边应用的冻干型反转录重组酶扩增测定法快速检测麝香鸭轮状病毒
Xiuqin Chen,Shizhong Zhang,Xiaochun Luo et al.
Xiuqin Chen et al.
Muscovy duck reovirus (MDRV) causes substantial economic losses in the waterfowl industry, necessitating rapid and field-deployable diagnostic tools. In this study, we developed, for the first time, a lyophilized reagent-based reverse trans...
Emergence and Genetic Characteristics of H5N1, H5N6, and H5N3 Clade 2.3.4.4b High Pathogenicity Avian Influenza Viruses in South Korea During the 2023-2024 and 2024-2025 Winter Seasons [0.03%]
2023至2024年和2024至2025年冬季在韩国出现的H5N1、H5N6和H5N8禽流感病毒（2.3.4.4b分支）的遗传特征分析
Ra Mi Cha,Yunyueng Jang,Min-Ji Park et al.
Ra Mi Cha et al.
Since 2020, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses (HPAIVs) have consistently spread across continents, causing outbreaks worldwide. During the 2023-2024 (23/24) and 2024-2025 (24/25) winter seasons, clade 2.3.4.4b H...
Portable Molecular Diagnostics for Cetacean Morbillivirus: Development of a Reverse Transcription Insulated Isothermal PCR (RT-iiPCR) for Global Surveillance [0.03%]
便携式鲸类莫尼特病毒分子诊断技术的开发：环介导反转录等温PCR法用于全球监测
Chricel Lattao,Cheng-Chen Hsieh,Marie Christine M Obusan et al.
Chricel Lattao et al.
Cetacean morbillivirus (CeMV) drives recurrent unusual-mortality events, yet surveillance is uneven where laboratory capacity is limited. We developed a portable reverse transcription-insulated isothermal PCR (RT-iiPCR) assay targeting a co...