Discovery of a Structurally Stable Immunodominant Region in ASFV p30 C-Terminus Using a Panel of Monoclonal Antibodies [0.03%]
利用单克隆抗体文库鉴定非洲猪瘟病毒p30羧基端结构稳定且免疫优势区域
Wei Liu,Shandian Gao,Jiaoyan Su et al.
Wei Liu et al.
African swine fever (ASF) is a lethal hemorrhagic viral disease of pigs with devastating global socioeconomic impacts. Due to the absence of a safe and effective vaccine, early surveillance and precise diagnostics are critical for ASF preve...
Ana M Palomar,Aránzazu Portillo,Asunción Gómez et al.
Ana M Palomar et al.
Wildlife is an important source of emerging zoonotic agents, including tick-borne ones. Wild carnivores such as mink are commonly parasitized by ticks, which are vectors and reservoirs of zoonotic diseases. Besides the importance of these a...
Serotype Diversity and Molecular Characterization of Foot-and-Mouth Disease Viruses From Outbreaks in Ethiopia (2019-2023): Re-Emergence of SAT 2 After 30 Years [0.03%]
2019-2023年埃塞俄比亚爆发的口蹄疫病毒血清型多样性及分子特征分析:SAT 2型30年后再现
Daniel Gizaw,Bayeta Senbata,Aynalem Fentie et al.
Daniel Gizaw et al.
Ethiopia faces significant economic losses from foot-and-mouth disease (FMD). Laboratory diagnostic tools such as antigen detection ELISA (Ag-ELISA), reverse transcription polymerase chain reaction (RT-PCR), and sequencing provide important...
Seasonal and Regional Dynamics of Mastitis Pathogens: Insights From a 3-Year Study in China [0.03%]
中国一项为期三年的研究揭示了乳腺炎病原菌的季节性和地区性动态特征
Yawei Qiu,Shaodong Fu,Naiyan Sun et al.
Yawei Qiu et al.
Mastitis is one of the biggest problems and an economic burden facing the dairy industry with a strong negative impact on animal welfare, productivity, and food safety. This study conducted a systematic investigation and analysis of the epi...
Global Transmission and Evolution of Chikungunya Virus: Origins, Adaptive Mutations, and Intercontinental Spread of the Three Genotypes [0.03%]
基孔肯雅病毒的全球传播和进化:三种基因型的起源、适应性突变及洲际传播
Yujia Hao,Qingmiao Fan,Fan Yu et al.
Yujia Hao et al.
Chikungunya virus (CHIKV) is an arthropod-borne virus that has caused several major outbreaks around the world and is becoming increasingly harmful. Although significant progress has been made in understanding the global epidemiology and tr...
Comparison of Gross Lesions in Poultry Naturally Infected With High Pathogenicity Avian Influenza H5N6 and H5N1 Viruses in South Korea, 2023-2025 [0.03%]
2023-2025年韩国高致病性禽流感H5N6和H5N1病毒自然感染家禽数字外病变的比较
Hye-Ryoung Kim,Kwang-Nyeong Lee,Youn-Jeong Lee et al.
Hye-Ryoung Kim et al.
High pathogenicity avian influenza (HPAI) is an acute infectious disease of poultry and wild birds that has been occurring worldwide and has been controlled in many countries by culling birds on farms with disease outbreaks. We compared the...
Comparative Study
Transboundary and emerging diseases. 2025 Nov 25:2025:1736453. DOI:10.1155/tbed/1736453 2025
Pseudorabies Virus UL41 Hijacks IFN Response via JAK/STAT Pathway While Cellular TRIM21 Blocks it Through K48 Ubiquitination [0.03%]
伪狂犬病毒UL41劫持JAK/STAT信号通路的宿主IFN反应,而细胞TRIM21通过K48泛素化抑制它
Xue Li,Jiawei Zheng,Guoqing Zhang et al.
Xue Li et al.
Pseudorabies virus (PRV), a significant pathogen that infects various animals, including pigs, encodes multiple proteins that participate in host-pathogen interactions. This study investigates the mechanisms by which PRV evades host immune ...
Bo-Kang Fu,Tian Tang,Ming Yue et al.
Bo-Kang Fu et al.
Understanding the ecological niches and quantifying the disease burden of Babesia species is essential for efficient surveillance and control strategies. Through a systematic review of global distributions, we document all 250 identified Ba...
Design of Mucosal Vaccines Against Swine Enteric Coronaviruses: From Antigen Delivery to Immune Activation [0.03%]
猪肠炎冠状病毒黏膜疫苗的设计:从抗原递送到免疫激活
Qihao Pan,Yinhe Sun,Haojie Bai et al.
Qihao Pan et al.
Swine enteric coronaviruses (SeCoVs) cause acute enteritis and high mortality in neonatal piglets, posing a significant threat to the swine industry. Injectable vaccines often fail to induce effective mucosal immunity, and their efficacy is...
Isolation, Genomic Characterization, and Pathogenicity of a Novel Duck Orbivirus Genetically Similar to Corriparta Virus in China [0.03%]
中国新型家鸭 orbivirus(基因与 Corriparta病毒相似)的分离、全基因组分析及致病性研究
Liping Liu,Xiaozhen Guo,Feng Hu et al.
Liping Liu et al.
Corriparta virus (CORV), an arbovirus within the Orbivirus genus, exhibits a broad vertebrate host range but limited pathogenicity. In this study, we report the first isolation and characterization of a novel orbivirus genetically related t...