A Scoping Review of Machine Learning Applications Across Epidemiological Stages of Zoonotic Disease [0.03%]
关于机器学习在传染病流行病学各个阶段应用的综述研究
Yinsheng Zhang,Yifan Sun,Jinchen Wang et al.
Yinsheng Zhang et al.
Emerging zoonotic diseases represent a significant threat to global health. While machine learning (ML) holds promise for their management, a comprehensive understanding of how these technologies are applied across the entire animal-to-huma...
Genomic and Pathogenic Characterization of an Extensively Drug-Resistant Avian Pathogenic Escherichia coli Strain [0.03%]
一种广泛耐药的致病性禽源大肠杆菌菌株的基因组及致病性特征分析
Weishi Ni,Lijuan Chen,Hao Chen et al.
Weishi Ni et al.
Extensively drug-resistant (XDR) avian pathogenic Escherichia coli (APEC) poses a global threat to poultry and public health. In this study, we isolated an APEC strain, SDLYRA415, from broilers in Shandong, China, during an outbreak with ~2...
Establishment of a Tetra-Primer ARMS-PCR Assay to Discriminate Genotypes I and II African Swine Fever Viruses [0.03%]
建立一种鉴别非洲猪瘟病毒基因Ⅰ型和基因Ⅱ型的 tetra-primer arm PCR 方法
Leilei Ding,Kun Xue,Tao Ren et al.
Leilei Ding et al.
The African swine fever virus (ASFV), particularly the genotypes I and II strains that have spread beyond Africa, continues to threaten global swine production and food security. Currently, African swine fever (ASF) control strategies rely ...
Isolation and Transcriptomic Characterization of Genotype 5 Japanese Encephalitis Virus E138K Mutant Strain [0.03%]
单克隆分离并进行转录组测序的乙型脑炎病毒E138K突变株（基因5型）
Yuhong Yang,Ruichen Wang,Weijia Zhang et al.
Yuhong Yang et al.
The recent emergence of the genotype five Japanese encephalitis virus (G5 JEV) has once again drawn public attention to public health concerns. Plaque assay analysis of G5 JEV parental strain XZ0934 revealed two distinct plaque morphologies...
Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next-Generation Veterinary Vaccines [0.03%]
用于抗原递呈的工程化PCV2 VLPs：下一代兽医疫苗平台
Peiyang Ding,Yating Liu,Chenyu Wang et al.
Peiyang Ding et al.
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self-assembles into virus-like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs dis...
Detection and Genomic Characterization of Novel Respiratory Viruses in US and Mexican Cattle Farms [0.03%]
美国和墨西哥 cattle farm 中新型呼吸道病毒的检测与基因组特征分析
Judith U Oguzie,Daniel B Cummings,John T Groves et al.
Judith U Oguzie et al.
Respiratory virus infections in cattle cause an estimated more than $1 billion in production losses and can threaten human health. During February 2024 to May 2025, we employed a One Health approach to surveil for respiratory viruses among ...
Eprinomectin Inhibits Leishmania by Inducing Mitochondrial Dysfunction and Cell Cycle Arrest [0.03%]
依普林美克丁通过诱导线粒体功能障碍和细胞周期阻滞来抑制利什曼原虫
Mengtao Yu,Jiale Guo,Wenqi Liu et al.
Mengtao Yu et al.
Introduction: Leishmaniasis remains a significant global health challenge, with current therapies often hampered by toxicity, resistance, and high cost. In this study, we investigated the antileishmanial potential of epri...
Resilience of Belgian Cattle Farmers Towards Infectious Diseases Outbreaks [0.03%]
比利时畜牧业者应对传染病爆发的韧性分析
Véronique Renault,Laurent Delooz,Marie-France Humblet et al.
Véronique Renault et al.
The study addresses the growing risk of infectious disease outbreaks in livestock by developing and applying a composite resilience index to evaluate the adaptive capacity of Belgian cattle farmers in implementing biosecurity measures (BSMs...
Toxoplasma gondii KCR is a Noncanonical Modulator of CSF2 Signaling that Targets the CSF2Rα-JAK2/STAT5 Axis [0.03%]
托拉原虫KCR是一种非 canonical CSF2信号调控因子，作用于CSF2Rα-JAK2/STAT5轴
Jie Mei,Xianglin Pu,Mengkai Zhang et al.
Jie Mei et al.
Toxoplasma gondii establishes infection in hosts by deploying effector proteins that reprogram cytokine-driven immunity. While protozoan parasite-encoded macrophage migration inhibitory factor (MIF) homologs exemplify cytokine mimicry, whet...
A Self-Amplifying RNA Lipid Nanoparticle (saRNA-LNP) Vaccine Provides Effective Protection Against Porcine Epidemic Diarrhea [0.03%]
一种自我增效的RNALNPs疫苗可有效预防猪流行性腹泻病毒感染
Jinqi Shu,Han Zhang,Fang Wang et al.
Jinqi Shu et al.
The development of vaccine platforms capable of inducing sustained, potent, and cost-effective immunity remains a major challenge in veterinary vaccinology, particularly for coronaviruses, which are often associated with short-lived vaccine...