Synthesis of tertiary alkyl amines via photoinduced copper-catalysed nucleophilic substitution [0.03%]
光诱导铜催化亲核取代合成三级烷基胺
Hyungdo Cho,Xiaoyu Tong,Giuseppe Zuccarello et al.
Hyungdo Cho et al.
In view of the high propensity of tertiary alkyl amines to be bioactive, the development of new methods for their synthesis is an important challenge. Transition-metal catalysis has the potential to greatly expand the scope of nucleophilic ...
Stereoselective amino alcohol synthesis via chemoselective electrocatalytic radical cross-couplings [0.03%]
手性氨基醇的化学选择性电催化自由基交叉偶联立体选择性合成
Jiawei Sun,Shuanghu Wang,Kaid C Harper et al.
Jiawei Sun et al.
Amino alcohols are vital in natural products, pharmaceuticals and agrochemicals, and as key building blocks for various applications. Traditional synthesis methods often rely on polar bond retrosynthetic analysis, requiring extensive protec...
Adaptive metal ion transport and metalloregulation-driven differentiation in pluripotent synthetic cells [0.03%]
可变金属离子运输和金属调节驱动的多能合成细胞分化
Sayuri L Higashi,Yanjun Zheng,Taniya Chakraborty et al.
Sayuri L Higashi et al.
Pluripotent cells can yield different cell types determined by the specific sequence of differentiation signals that they encounter as the cell activates or deactivates functions and retains memory of previous inputs. Here, we achieved plur...
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes [0.03%]
吡哆醛磷酸依赖性酶促进林可酰胺多样化的分子机制
Takahiro Mori,Yoshitaka Moriwaki,Kosuke Sakurada et al.
Takahiro Mori et al.
The biosynthesis of the lincosamide antibiotics lincomycin A and celesticetin involves the pyridoxal-5'-phosphate (PLP)-dependent enzymes LmbF and CcbF, which are responsible for bifurcation of the biosynthetic pathways. Despite recognizing...
Stacey Paiva
Stacey Paiva
The mystery of crotonyl-CoA [0.03%]
克罗通酰辅酶A之谜
Marinda Westerveld,Rita Petracca
Marinda Westerveld
Evolving learning styles [0.03%]
演变中的学习风格
Shira Joudan
Shira Joudan
Electrochemical formation of bis(fluorosulfonyl)imide-derived solid-electrolyte interphase at Li-metal potential [0.03%]
在锂金属电位下形成双（氟磺酰）亚胺衍生的固态电解质界面膜的电化学过程
Weilai Yu,Kuan-Yu Lin,David T Boyle et al.
Weilai Yu et al.
Lithium bis(fluorosulfonyl)imide-based liquid electrolytes are promising for realizing high coulombic efficiency and long cycle life in next-generation Li-metal batteries. However, the role of anions in the formation of the solid-electrolyt...
Competitive exclusion among self-replicating molecules curtails the tendency of chemistry to diversify [0.03%]
竞争性排除限制了能够自我复制的大分子的化学多样性趋势
Marcel J Eleveld,Yannick Geiger,Juntian Wu et al.
Marcel J Eleveld et al.
The transition of chemistry into biology is poorly understood. Key questions include how the inherently divergent nature of chemical reactions can be curtailed, and whether Darwinian principles from biology extend to chemistry. Addressing b...