Effects of iron deficiency anemia on maternal hemodynamics and cardiac function in pregnant spontaneously hypertensive rats [0.03%]
缺铁性贫血对妊娠期自发性高血压大鼠母体血流动力学及心功能的影响
Jad-Julian R Rachid,Jennie Vu,Si Ning Liu et al.
Jad-Julian R Rachid et al.
Aim: Hypertensive disorders of pregnancy (HDP) are characterized by adverse or inadequate maternal cardiovascular adaptations and are associated with poor perinatal outcomes. Iron deficiency (ID) is a common pregnancy com...
Mapping disease-specific vascular cell populations responsible for obliterative arterial remodeling during development of pulmonary arterial hypertension [0.03%]
在肺动脉高压发病过程中血管特异细胞群导致重塑病变的图谱研究
Nicholas D Cober,Emma McCourt,Rafael Soares Godoy et al.
Nicholas D Cober et al.
Background: Pulmonary arterial hypertension (PAH) is a lethal pulmonary vascular disease characterized by arteriolar pruning and occlusive vascular remodeling leading to increased pulmonary vascular resistance and eventua...
Luke Spray,Gavin Richardson,Laura K Booth et al.
Luke Spray et al.
Most acquired cardiovascular diseases are more common in older people, and the biological mechanisms and manifestations of aging provide insight into cardiovascular pathophysiology. Measuring aging within the cardiovascular system may help ...
Diane Fatkin,Renee Johnson
Diane Fatkin
Loss of primary cilia triggers leaflet remodelling and bicuspid aortic valve formation [0.03%]
原纤毛丢失引发瓣叶重塑并导致主动脉双叶瓣形成
Damien Marchese,Stéphane Zaffran
Damien Marchese
Blood pressure management in secondary prevention after myocardial infarction [0.03%]
心肌梗死后二级预防中的血压管理
Massimo Volpe,Giovanna Gallo,Tomasz J Guzik et al.
Massimo Volpe et al.
The management of blood pressure (BP) in secondary prevention after acute myocardial infarction (AMI) remains a matter of debate. Since no dedicated trials have specifically addressed BP control in patients recovering from an acute coronary...
Wieteke Broeders,Amber van Broekhoven,Aysun Cetinyurek-Yavuz et al.
Wieteke Broeders et al.
A "second hit" mouse model for group 2 and 3 pulmonary hypertension: Combination of aortic banding and hypoxia exposure [0.03%]
一种用于第2组和第3组肺动脉高压的“二次打击”小鼠模型：结合主动脉缩窄和低氧暴露
Laura K Pallos,Michaela Matthey,Michael Hesse et al.
Laura K Pallos et al.
Eicosapentaenoic acid (EPA) limits the more rapid oxidation of lipoprotein(a) [Lp(a)] compared with other ApoB particles [0.03%]
二十碳五烯酸(EPA)可减缓与其它载脂蛋白B颗粒相比更易发生的脂蛋白(a)[Lp(a)]的氧化反应
Samuel C R Sherratt,Peter Libby,Richard L Dunbar et al.
Samuel C R Sherratt et al.
Aims: Elevated Lp(a) levels increase cardiovascular (CV) risk. Lp(a) contains oxidized phospholipids that may promote lipid oxidation more than other lipoproteins. The highly unsaturated omega-3 fatty acid EPA has multipl...
Gene therapy in cardiac and vascular diseases: a review of approaches to treat genetic and common cardiovascular diseases with novel gene-based therapeutics [0.03%]
心血管基因治疗综述：用新型基因药物治疗遗传性和常见的心血管疾病
Patricia L Musolino,Susan J Rosser,Mairi Brittan et al.
Patricia L Musolino et al.
In the past decade, there has been substantive progress in gene therapy across disease indications. However, despite multiple gene therapies being approved for clinical use, none have a cardiovascular indication. Several reasons for this ha...