Immunomodulatory endothelial cells contribute to T cell recruitment and activation via antigen presentation on MHC II [0.03%]
免疫调节内皮细胞通过MHCII类抗原呈递参与T细胞募集和活化
Matteo Cartura,Blerina Aliraj,Witold Szymański et al.
Matteo Cartura et al.
Aims: A subset of endothelial cells referred to as immunomodulatory endothelial cells (IMEC) has been proposed to regulate T cell responses in atherosclerosis and after myocardial infarction. Here, we studied the inflamma...
Syntabulin promotes heart failure by enhancing SR-mitochondria tethering and impairing mitofission [0.03%]
_syntaxabulin通过增强内质网-线粒体连接并抑制线粒体分裂促进心力衰竭_
Ying Li,Ziquan Sun,Haixia Duan et al.
Ying Li et al.
Aims: Mitochondrial dysfunction is a critical driver of heart failure (HF). Syntabulin (SYBU), known for its role as a motor linker at the outer mitochondrial membrane in neuronal system, has recently been suggested as a ...
Shuaibo Huang,Nikolaos G Frangogiannis
Shuaibo Huang
A STING-mediated trialogue: co-ordinating the CD8+ T-cell assault in doxorubicin cardiomyopathy [0.03%]
DOXORTIC试验：协调多柔比星心肌病中CD8+T细胞的攻击
Hafid Ait-Oufella,Jean-Sébastien Silvestre
Hafid Ait-Oufella
Urea-cycle control of fibroblast energetics after myocardial infarction [0.03%]
心肌梗死后纤维母细胞能量代谢的尿素循环调控机制研究
Ram Abou Zaki,Assam El-Osta
Ram Abou Zaki
Loss of caveolar A1 adenosine receptor signalling blunts anti-adrenergic control in heart failure [0.03%]
腔窝A1腺苷受体信号的丧失会减弱心力衰竭中的抗肾上腺素控制作用
Marta Mazzola,Houcheng Wang,Di Lang et al.
Marta Mazzola et al.
Aims: Adenosine, acting through A1 adenosine receptors (A1ARs), exerts anti-adrenergic effects by inhibiting β1-adrenergic receptor (β1AR)-mediated cAMP production and contractility in the heart. While the functional in...
Macrophage recruitment is a hallmark of non-syndromic myxomatous mitral valve disease [0.03%]
巨噬细胞募集是非综合征性二尖瓣黏液样变性的特征现象
Benjamin Le Vely,Constance Delwarde,Claire Toquet et al.
Benjamin Le Vely et al.
Aims: Myxomatous mitral valve disease (MMVD) is a progressive cardiac disease characterized by extracellular matrix remodeling, leaflet thickening, and proteoglycan accumulation. Despite its significant contribution to ca...
Dragos A Duse,Nathalie H Schröder,Sotirios Akritidis et al.
Dragos A Duse et al.
Aims: Carbon dioxide (CO2) can regulate blood flow and is applied therapeutically in intensive care units to treat brain injury, as well as in balneotherapy for peripheral arterial disease (PAD) and diabetic angiopathy; h...
Global prevalence of pan-vascular diseases: A trend and health inequality analyses [0.03%]
全球泛血管疾病的流行情况：趋势与健康差异分析
Jing Yang,Beijian Zhang,Laihai Zhang et al.
Jing Yang et al.
Aims: Pan-vascular diseases pose a significant and growing global public health burden. However, the burden of pan-vascular diseases remains unknown, especially regarding its trends through 2050. ...