Loss of caveolar A1 adenosine receptor signalling blunts anti-adrenergic control in heart failure
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Aims: Adenosine, acting through A1 adenosine receptors (A1ARs), exerts anti-adrenergic effects by inhibiting β1-adrenergic receptor (β1AR)-mediated cAMP production and contractility in the heart. While the functional interactio... ...
