Polycystin-1 suppresses apoptotic signalling in endothelial cells and protects from atherosclerosis [0.03%]
多囊蛋白-1通过抑制内皮细胞凋亡信号来抵抗动脉粥样硬化
B Tardajos Ayllon,J Gras Font,T A E Winks et al.
B Tardajos Ayllon et al.
Aims: Polycystin-1 (PKD1) and -2 (PKD2) are causative genes for autosomal dominant polycystic kidney disease (ADPKD), which often presents with cardiovascular manifestations by mechanisms still not completely understood. ...
Polycystin-1 suppresses apoptotic signalling in endothelial cells and protects from atherosclerosis [0.03%]
多囊蛋白-1通过抑制内皮细胞凋亡信号来抵抗动脉粥样硬化病变形成
B Tardajos Ayllon,J Gras Font,T A E Winks et al.
B Tardajos Ayllon et al.
Aims: Polycystin-1 (PKD1) and -2 (PKD2) are causative genes for autosomal dominant polycystic kidney disease (ADPKD), which often presents with cardiovascular manifestations by mechanisms still not completely understood. ...
Reduced Cx43 S-nitrosylation protects against cardiac stress-induced arrhythmias and myocardial injury in Duchenne Muscular Dystrophy [0.03%]
降低Cx43 S-硝基化可预防杜氏肌营养不良心脏应激诱导的心律失常和心肌损伤
Manuel F Muñoz,Pablo S Gaete,Jonathan J Quan et al.
Manuel F Muñoz et al.
Aims: In Duchenne muscular dystrophy (DMD), connexin-43 (Cx43) delocalizes from intercalated discs to the lateral membrane of cardiomyocytes, where it forms undocked hemichannels. β-adrenergic stress induces lethal arrhy...
Reduced Cx43 S-nitrosylation protects against cardiac stress-induced arrhythmias and myocardial injury in Duchenne Muscular Dystrophy [0.03%]
降低Cx43 S-硝基化可预防杜氏肌营养不良心脏应激诱导的心律失常和心肌损伤
Manuel F Muñoz,Pablo S Gaete,Jonathan J Quan et al.
Manuel F Muñoz et al.
Aims: In Duchenne muscular dystrophy (DMD), connexin-43 (Cx43) delocalizes from intercalated discs to the lateral membrane of cardiomyocytes, where it forms undocked hemichannels. β-adrenergic stress induces lethal arrhy...
Christopher X Wong,Gregory M Marcus
Christopher X Wong
Dogacan Yucel,Michael A Trembley,Qingen Ke et al.
Dogacan Yucel et al.
Aims: Ageing is the strongest risk factor for heart failure, yet the molecular mechanisms underlying cardiomyocyte (CM) ageing remain unclear. We aimed to map the transcriptomic and epigenomic landscape of CM ageing and t...
Differential cardiac remodeling: patterns of cardiomyocyte morphometry in multiple patient conditions [0.03%]
差异性心脏重塑：多病种患者心肌细胞形态计量的模式分析
Sandeep Manandhar,Yuxin Wu,Tilak Pathak et al.
Sandeep Manandhar et al.
Aims: Cardiac remodeling drives heart failure (HF), yet microstructural drivers in human tissue remain poorly defined due to the limited resolution of clinical imaging. This study sought to quantitatively assess cardiomyo...
A distinct T cell receptor signature associates with cardiac outcome in myocardial infarction patients [0.03%]
独特的T细胞受体标志与心肌梗死患者的临床预后相关性研究
Kenz Le Gouge,DiyaaElDin Ashour,Margarete Heinrichs et al.
Kenz Le Gouge et al.
Autonomous 0.3-Hz breathing causes slow 0.1-Hz brain-heart oscillations in humans [0.03%]
自主的0.3 Hz呼吸在人类中引起缓慢的0.1 Hz脑-心振荡
Gert Pfurtscheller,Maciej Kaminski,Beate Rassler et al.
Gert Pfurtscheller et al.
CKD disrupts cardiac energy metabolism and aggravates cardiac inflammation, oxidative stress, and dysfunction post-infarction [0.03%]
慢性肾脏病会扰乱心脏能量代谢并加重心梗后的心肌炎症、氧化应激和心脏功能障碍
Corinna Schulte,Julia Wollenhaupt,Sina Hourtz et al.
Corinna Schulte et al.
Aims: Patients with chronic kidney disease (CKD) display a reduced survival following myocardial infarction (MI). As the underlying mechanisms remain unclear, we examined the impact of CKD on cardiac remodeling and functi...