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Polycystin-1 suppresses apoptotic signalling in endothelial cells and protects from atherosclerosis

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Aims: Polycystin-1 (PKD1) and -2 (PKD2) are causative genes for autosomal dominant polycystic kidney disease (ADPKD), which often presents with cardiovascular manifestations by mechanisms still not completely understood. PKD1 and... ...