Identification of a new gain-of-function variant p.N536Y of KCNMA1 associated with PNKD3 in the Chinese population [0.03%]
与中国人群中PNKD3相关的KCNMA1新功能获得型变异p.N536Y的鉴定
Yufeng Huang,Lina Liang,Xuebin Xu et al.
Yufeng Huang et al.
Neuronal activity modulates the expression of secretagogin, a Ca2+ sensor protein, during mammalian forebrain development [0.03%]
神经元活动调节哺乳动物前脑发育过程中的一种Ca2+感应蛋白secretagogin的表达
János Hanics,Evgenii O Tretiakov,Roman A Romanov et al.
János Hanics et al.
Aim: Because of their stable expression, some EF-hand Ca2+-binding proteins are broadly used as histochemical markers of neurons in the nervous system. Secretagogin is a member of "neuron-specific" Ca2+-sensor proteins, y...
Ruizhi Li,Lei Ma,Yingchun Geng et al.
Ruizhi Li et al.
The microvascular system is essential for delivering oxygen and nutrients to tissues while removing metabolic waste. During pregnancy, the uteroplacental microvascular system undergoes extensive remodeling to meet the increased demands of t...
Henrik Dimke
Henrik Dimke
Host-microbiome homeostasis: Unveiling the complex interactions shaping health and disease [0.03%]
宿主-微生物群稳态：揭示影响健康与疾病的复杂相互作用
Pontus B Persson
Pontus B Persson
Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus [0.03%]
肾NHE1缺乏加重锂诱导的肾性尿崩症
Gabriella Blanco,Jianxiang Xue,Linto Thomas et al.
Gabriella Blanco et al.
Aims: The sodium-hydrogen exchanger isoform 1 (NHE1) is important for transepithelial Na+/H+ transport, intracellular pH, and cell volume regulation. NHE1 also transports Li+, preferably compared to NHE3, and the lack of ...
Hypoxia and ischemic stroke modify cerebrovascular tone by upregulating endothelial BK(Ca) channels-Lessons from rat, pig, mouse, and human [0.03%]
低氧和缺血性中风通过上调内皮BK(Ca)通道修改脑血管音调-来自大鼠，猪，小鼠和人类的教训
Christian Staehr,Victoria Hinkley,Vladimir V Matchkov et al.
Christian Staehr et al.
Aim: In animal models and human cerebral arteries, the changes in endothelial cell (EC)-large conductance calcium-activated potassium channel (BKCa) distribution, expression, and function were determined in hypoxia and is...
Les lésions anciennes: Evolution conserves noradrenergic regulation of astroglial homeostatic support [0.03%]
古老的损伤：保守的交感神经调节对星形胶质细胞稳态支持的演变
Alexei Verkhratsky
Alexei Verkhratsky
Cold-induced fibrosis and metabolic remodeling in the turtle (Trachemys scripta) ventricle [0.03%]
龟（Trachemys scripta）心室由寒冷诱导的纤维化和代谢重塑
Adam N Keen,James C McConnell,John J Mackrill et al.
Adam N Keen et al.
Aim: Cardiac fibrosis contributes to systolic and diastolic dysfunction and can disrupt electrical pathways in the heart. There are currently no therapies that prevent or reverse fibrosis in human cardiac disease. However...
Slow rather than fast calcium events encode physiological inputs and propagate within islets: Lessons from ultrafast imaging on acute pancreatic tissue slices [0.03%]
缓慢而非快速的钙信号事件编码生理输入并在胰岛内传播：来自急性胰腺组织切片超高速成像的启示
Matthieu Raoux,Dorian Chapeau,Jochen Lang
Matthieu Raoux