Acute Normobaric Hypoxia Reveals Blunted Chemoreflex and Autonomic Dysfunction in Asymptomatic Post-COVID-19 Patients [0.03%]
急性常压低氧条件下无症状新冠后遗症患者化学感受器反射和自主神经功能减退
Elissa Silva de Farias Mello,André Luiz Musmanno Branco Oliveira,Pedro Paulo da Silva Soares et al.
Elissa Silva de Farias Mello et al.
Rudolf Schubert
Rudolf Schubert
Physiology of K+ Homeostasis in Cerebrospinal Fluid: The Fine-Tuning Role of the Choroid Plexus Kir7.1 Channel [0.03%]
脑脊液钾稳态的生理作用：脉络丛Kir7.1通道的作用机制
Peng Long,Gelei Xiao
Peng Long
Endothelial Cell Organization Drives Distinct Agonist-Specific Ca2+ Dynamics in Arteries and Veins [0.03%]
内皮细胞组织决定动脉和静脉特异激动剂的钙离子动力学现象
M D Lee,R A Clark,C Buckley et al.
M D Lee et al.
Aim: The endothelium regulates cardiovascular function by detecting and interpreting multiple extracellular signals from blood and surrounding tissues, even when these inputs are complex and conflicting. The major challen...
A 12-Week Strength Training Improves Mitochondrial Respiration, H2O2 Emission and Skeletal Muscle Integrity in Women With Myotonic Dystrophy Type 1 [0.03%]
12周的力量训练可以改善I型肌营养不良女性患者肌肉线粒体的呼吸作用和H2O2释放以及改善骨骼肌结构
Vincent Marcangeli,Laura Girard-Côté,Valeria Di Leo et al.
Vincent Marcangeli et al.
Background: Myotonic dystrophy type 1 (DM1) is caused by expanded CTG repeats in the DMPK gene, causing the accumulation of toxic RNA that sequesters RNA-binding proteins. Clinically, DM1 is characterized by progressive m...
Factors Influencing Blood Lactate Concentration During Exercise: A Narrative Review With a Lactate Shuttle Perspective [0.03%]
运动过程中影响血液乳酸浓度的因素：以乳酸 shuttle 为核心的叙述性评论
José Antonio Benítez-Muñoz,Rocío Cupeiro
José Antonio Benítez-Muñoz
Aim: Blood lactate concentration ([La-]), usually measured in mmol/L, is one of the most frequently measured parameters during clinical exercise tests as well as during performance assessments of athletes. Therefore, the ...
Effects of Heat Exposure on Kynurenine Pathway Metabolism-Comparison Between Exertional and Exogenous Heating of the Human Body [0.03%]
热暴露对犬尿氨酸代谢的影响-人体运动性与外来加热的比较研究
Varvara Louvrou,Nerijus Eimantas,Ema Juškevičiūtė et al.
Varvara Louvrou et al.
Background: The kynurenine pathway (KP) plays a pivotal role in many diseases that involve distinct pathological mechanisms. Objectives: ...
Randomized Controlled Trial
Acta physiologica (Oxford, England). 2025 Dec;241(12):e70123. DOI:10.1111/apha.70123 2025
Maternal Diet-Induced Excess Adiposity in Mice Disrupts Mid-Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling [0.03%]
母体饮食诱导的小鼠过量脂肪堆积会干扰中期妊娠蜕膜免疫和血管稳态而不会影响螺旋动脉重塑
Christian J Bellissimo,Erica Yeo,Tatiane A Ribeiro et al.
Christian J Bellissimo et al.
Aim: Maternal excess adiposity (i.e., overweight/obesity) is linked to impaired uteroplacental perfusion, compromised placental development, and increased risk of adverse pregnancy outcomes. Inflammation and immune dysreg...
Role of the Choroid Plexus Kir7.1 Channel in the Regulation of Mouse Cerebrospinal Fluid K+ Concentration [0.03%]
Kir7.1通道在调节小鼠脑脊液K+浓度的胆碱作用
Juan Carlos Henao,Johanna Burgos,Erwin Vera et al.
Juan Carlos Henao et al.
Aim: K+ channel Kir7.1 is prominently expressed at the apical membrane of the choroid plexus epithelium (CPE) together with the Na+-K+-ATPase pump and cotransporter NKCC1. Its unusual independence of extracellular K+ ([K+...